sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ykl | GMP | Aprataxin-like protein | 3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ykl | GMP | Aprataxin-like protein | 3 | 1.000 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.543 | |
| 4xba | GMP | Aprataxin-like protein | 3 | 0.496 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.482 | |
| 3pzc | COA | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.477 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.465 | |
| 2cdu | FAD | NADH oxidase | / | 0.463 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.463 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 4h2w | 5GP | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.460 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.459 | |
| 3fx6 | BPX | Carboxypeptidase A1 | 3.4.17.1 | 0.459 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.457 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.457 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.452 | |
| 4g3q | UD1 | Bifunctional protein GlmU | / | 0.451 | |
| 4m37 | SAH | Protein arginine N-methyltransferase 7 | 2.1.1 | 0.451 | |
| 4nv0 | MG7 | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.451 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.450 | |
| 4n9w | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.449 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.447 | |
| 3rme | RME | Acidic mammalian chitinase | 3.2.1.14 | 0.447 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.446 | |
| 1xh6 | R94 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.444 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.442 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.441 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.440 |