Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4xsdUMPThymidylate synthase2.1.1.45

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4xsdUMPThymidylate synthase2.1.1.451.000
4irrUMPThymidylate synthase/0.544
5by6UMPThymidylate synthase/0.526
3dg8UMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.521
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.520
4einNOHThymidylate synthase2.1.1.450.520
4dpdUMPBifunctional dihydrofolate reductase-thymidylate synthase/0.518
3qj7UMPThymidylate synthase ThyA/0.516
4eb4UMPThymidylate synthase2.1.1.450.516
4dq1UMPThymidylate synthase/0.509
4iskUMPThymidylate synthase/0.509
4psgNOHThymidylate synthase/0.504
1ci7UMPThymidylate synthase2.1.1.450.502
4e5oUMPThymidylate synthase2.1.1.450.485
1njdUMPThymidylate synthase/0.484
4foxUMPThymidylate synthase ThyA/0.483
1tsvUMPThymidylate synthase/0.472
1bidUMPThymidylate synthase/0.471
1dduDDUThymidylate synthase/0.471
1tsxUMPThymidylate synthase/0.469
1b5dDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.468
1njbUMPThymidylate synthase/0.468
2g8aUMPThymidylate synthase/0.467
1jmgUMPThymidylate synthase/0.466
1njcDCMThymidylate synthase/0.460
1bp6UMPThymidylate synthase/0.459
1jmiUMPThymidylate synthase/0.459
3bgxTMPThymidylate synthase/0.457
2g89UMPThymidylate synthase/0.456
3hb8UMPThymidylate synthase2.1.1.450.455
2tsrUMPThymidylate synthase2.1.1.450.454
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.452
1jmhUMPThymidylate synthase/0.450
1jmfUMPThymidylate synthase/0.449
1njaDCMThymidylate synthase/0.448
1tsyUMPThymidylate synthase/0.447
1f28UMPThymidylate synthase2.1.1.450.441
1njeDCMThymidylate synthase/0.441
2g86UMPThymidylate synthase/0.441