sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4xjc | TTP | dCTP deaminase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4xjc | TTP | dCTP deaminase | / | 1.000 | |
| 2v9x | DUT | dCTP deaminase | / | 0.543 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.529 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.520 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.520 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.514 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.511 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.511 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.509 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.504 | |
| 4wrk | DUP | DUTPase | / | 0.504 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.502 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.500 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.499 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.498 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.498 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.498 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.497 | |
| 2ol0 | DUD | DUTP pyrophosphatase | / | 0.497 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.497 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.496 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.496 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.496 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.496 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.496 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.494 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.493 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.492 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.491 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.491 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.490 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.490 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.489 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.489 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.488 | |
| 1sve | I01 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.486 | |
| 1xs4 | DCP | dCTP deaminase | / | 0.486 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.485 | |
| 2pxa | SAH | Genome polyprotein | 2.7.7.48 | 0.485 | |
| 3bnk | FMN | Flavoredoxin | / | 0.485 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.485 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.485 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.484 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.483 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.483 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.482 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.482 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.482 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.482 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.481 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.481 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.481 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.480 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.480 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.480 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.479 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.479 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.478 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.478 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.478 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.478 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.478 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.478 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.477 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.477 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.476 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.476 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 3qen | 5BT | Deoxycytidine kinase | 2.7.1.74 | 0.476 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.476 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.476 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.475 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.475 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.475 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4ctj | SAM | Genome polyprotein | / | 0.475 | |
| 4dtb | GMP | APH(2'')-Id | / | 0.475 | |
| 4eox | 0S5 | Peptide deformylase | / | 0.475 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.475 | |
| 2bju | IH4 | Plasmepsin-2 | 3.4.23.39 | 0.474 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.474 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.474 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.474 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.474 | |
| 4xr9 | NAD | CalS8 | / | 0.474 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.473 | |
| 1snf | UMP | Deoxyuridine 5'-triphosphate nucleotidohydrolase | 3.6.1.23 | 0.473 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.473 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.473 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.473 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.473 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.473 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.472 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.472 | |
| 3ke8 | EIP | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.472 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.472 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.471 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.471 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.471 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.471 | |
| 4yp1 | 2BA | Stimulator of interferon genes protein | / | 0.471 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.470 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.470 | |
| 2vnm | CM8 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3eld | SFG | Methyltransferase | / | 0.470 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.470 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.470 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.470 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.470 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.470 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.469 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.469 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.469 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.469 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.469 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.469 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.469 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.469 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.469 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.469 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.468 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 1zly | DQB | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.468 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 2oke | DUP | DUTP pyrophosphatase | / | 0.468 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.468 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.468 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.468 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.468 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 1e2n | RCA | Thymidine kinase | / | 0.467 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.467 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.467 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.467 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.467 | |
| 2vet | UMP | Thymidylate synthase | / | 0.467 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.467 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.467 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.467 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.466 | |
| 2ejz | SAH | Diphthine synthase | / | 0.466 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.466 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.466 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.466 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.466 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.466 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.465 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.465 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.465 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.465 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.465 | |
| 2pcm | SAH | Diphthine synthase | / | 0.465 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.465 | |
| 3ex8 | AIF | Riboflavin biosynthesis protein RibD | 1.1.1.193 | 0.465 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.465 | |
| 4ira | FAD | 4-hydroxyphenylacetate 3-monooxygenase | / | 0.465 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.465 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.465 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.465 | |
| 5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.465 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.465 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.464 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.464 | |
| 1vyq | DUX | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.464 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.464 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.464 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.464 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.464 | |
| 2q9c | GNP | Signal recognition particle receptor FtsY | / | 0.464 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.464 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.464 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.464 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.464 | |
| 4e2z | JHZ | Methyltransferase | / | 0.464 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.464 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.464 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.463 | |
| 2dzb | HH2 | Dihydropteroate synthase | / | 0.463 | |
| 2emr | SAH | Diphthine synthase | / | 0.463 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.463 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
| 3lm8 | VIB | Thiamine pyrophosphokinase | 2.7.6.2 | 0.463 | |
| 3p97 | SAM | Genome polyprotein | 2.1.1.56 | 0.463 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.463 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.463 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.463 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.462 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.462 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.462 | |
| 1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.462 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.462 | |
| 2zja | ACP | ATP-dependent DNA helicase Hel308 | / | 0.462 | |
| 4cnf | MTA | SpoU rRNA methylase | / | 0.462 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 4k6m | SAH | Genome polyprotein | / | 0.462 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.462 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.461 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.461 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.461 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.461 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.461 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.461 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.461 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.460 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.460 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.460 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.460 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.460 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.460 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.460 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.460 | |
| 3h98 | B5P | Genome polyprotein | 2.7.7.48 | 0.460 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.460 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4yqf | GDP | Septin-9 | / | 0.460 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.460 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.459 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 1sl3 | 170 | Prothrombin | 3.4.21.5 | 0.459 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.459 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2f2u | M77 | Rho-associated protein kinase 2 | 2.7.11.1 | 0.459 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.459 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.459 | |
| 3fwy | ADP | Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein | / | 0.459 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.459 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.459 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.459 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.459 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.459 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.459 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.459 | |
| 4e47 | 0N6 | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.459 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.459 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.459 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.459 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.458 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 1n06 | ADP | Riboflavin kinase | 2.7.1.26 | 0.458 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.458 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.458 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.458 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.458 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 3ilt | TRU | Glutamate receptor 2 | / | 0.458 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.458 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.458 | |
| 3t6i | NC9 | Endothiapepsin | 3.4.23.22 | 0.458 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.458 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.458 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.458 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.458 | |
| 4yfy | 1YJ | VioF | / | 0.458 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.457 | |
| 1hi0 | GTP | RNA-directed RNA polymerase | 2.7.7.48 | 0.457 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1uze | EAL | Angiotensin-converting enzyme | 3.2.1 | 0.457 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.457 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.457 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.457 | |
| 3ua8 | 08W | Glutamate receptor 2 | / | 0.457 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.457 | |
| 3w23 | 3RO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.457 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.457 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.457 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.457 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.456 | |
| 1i5e | U5P | Uracil phosphoribosyltransferase | / | 0.456 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 1njj | ORX | Ornithine decarboxylase | / | 0.456 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.456 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 3q5d | GDP | Atlastin-1 | 3.6.5 | 0.456 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.456 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.456 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.455 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.455 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.455 | |
| 1kqb | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.455 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.455 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.455 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.455 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.455 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.455 | |
| 2e8t | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.455 | |
| 2vwh | NAP | Glucose 1-dehydrogenase | / | 0.455 | |
| 3krf | DST | Geranyl diphosphate synthase large subunit | / | 0.455 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.455 | |
| 3tlc | 7MD | Microcin C7 self-immunity protein MccF | / | 0.455 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.455 | |
| 4a6a | TTP | dCTP deaminase | 3.5.4.13 | 0.455 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.455 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.455 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.454 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.454 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.454 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.454 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.454 | |
| 1lbm | 137 | N-(5'-phosphoribosyl)anthranilate isomerase | 5.3.1.24 | 0.454 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.454 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.454 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.454 | |
| 2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.454 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.454 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.454 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.454 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.454 | |
| 4e31 | JHZ | Methyltransferase | / | 0.454 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.454 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.454 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.454 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.454 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.454 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.454 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.453 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.453 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.453 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.453 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.453 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.453 | |
| 2r8o | T5X | Transketolase 1 | / | 0.453 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.453 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.453 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.453 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.453 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.453 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.453 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.453 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.453 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.452 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.452 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.452 | |
| 1mc1 | PCX | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.452 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 1tv8 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.452 | |
| 1tvc | FDA | Methane monooxygenase component C | 1.14.13.25 | 0.452 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.452 | |
| 2emu | SAH | Diphthine synthase | / | 0.452 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.452 | |
| 2os1 | BB2 | Peptide deformylase | / | 0.452 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.452 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.452 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.452 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.452 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.452 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 4e2d | FMN | Dehydrogenase | / | 0.452 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.452 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.452 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.452 | |
| 5cho | FAD | Flavin reductase | / | 0.452 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.451 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.451 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.451 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 1thy | UMP | Thymidylate synthase | / | 0.451 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.451 | |
| 1zwl | FMN | NAD(P)H dehydrogenase (quinone) | 1.6.5.2 | 0.451 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.451 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.451 | |
| 2p5f | SAH | Diphthine synthase | / | 0.451 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.451 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.451 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.451 | |
| 3elu | SAM | Methyltransferase | / | 0.451 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.451 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.451 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.451 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.451 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4u7w | NDP | MxaA | / | 0.451 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.451 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.451 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.450 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.450 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 1o86 | LPR | Angiotensin-converting enzyme | 3.2.1 | 0.450 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 2d5n | NDP | Riboflavin biosynthesis protein RibD | 1.1.1.193 | 0.450 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.450 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.450 | |
| 2q0l | NAP | Thioredoxin reductase | 1.8.1.9 | 0.450 | |
| 2r8p | T6F | Transketolase 1 | / | 0.450 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
| 2x93 | X93 | Angiotensin-converting enzyme | 3.4.15.1 | 0.450 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.450 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.450 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.450 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.450 | |
| 3lcj | COA | Phosphopantetheine adenylyltransferase | / | 0.450 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.450 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.450 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.450 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.450 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.450 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 4z0g | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.450 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.449 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.449 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.449 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.449 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.449 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.449 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.449 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.449 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3rdq | DTB | Streptavidin | / | 0.449 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.449 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.449 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.449 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.449 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.449 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.449 | |
| 5aga | ANP | DNA polymerase theta | / | 0.449 | |
| 5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.449 | |
| 5jdz | SAH | Methyl transferase | / | 0.449 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.448 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.448 | |
| 1l5s | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.448 | |
| 1mxi | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.448 | |
| 1q6y | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.448 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.448 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.448 | |
| 2xfk | AA9 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.448 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.448 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.448 | |
| 3i12 | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.448 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3r0i | C0K | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.448 | |
| 3uf6 | COD | Lmo1369 protein | / | 0.448 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.448 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.448 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.448 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
| 4e2b | FMN | Dehydrogenase | / | 0.448 | |
| 4jb1 | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.448 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.448 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.448 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.448 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.448 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.447 | |
| 1nvm | NAD | Acetaldehyde dehydrogenase | 1.2.1.10 | 0.447 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.447 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.447 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.447 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.447 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.447 | |
| 2uxw | TH3 | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.9 | 0.447 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 3cwj | 321 | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3ely | SAH | Methyltransferase | / | 0.447 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.447 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.447 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3t7q | RB4 | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.447 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.447 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.447 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.447 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.447 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.447 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.447 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.447 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.447 | |
| 1bp6 | UMP | Thymidylate synthase | / | 0.446 | |
| 1gqy | ACP | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.446 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.446 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1kqd | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.446 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.446 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.446 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.446 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.446 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.446 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.446 | |
| 3ieu | GDP | GTPase Era | / | 0.446 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.446 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.446 | |
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.446 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.446 | |
| 4e2w | JHZ | Methyltransferase | / | 0.446 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.446 | |
| 4hdh | ATP | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.446 | |
| 4xcz | FON | Qdtf | / | 0.446 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.446 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.446 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.445 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.445 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.445 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.445 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.445 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.445 | |
| 1t57 | FMN | Conserved protein | / | 0.445 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.445 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.445 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.445 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.445 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.445 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.445 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.445 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 2vax | CSC | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.445 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.445 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.445 | |
| 3zgl | 10E | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.445 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.445 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.445 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.445 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.444 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.444 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.444 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.444 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1yki | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.444 | |
| 2fvc | 888 | Polyprotein | / | 0.444 | |
| 2i0d | MUT | Protease | / | 0.444 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.444 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.444 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.444 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.444 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.444 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.444 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.444 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.444 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.444 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.444 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.444 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.444 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.444 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.444 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1ixe | COA | Citrate synthase | / | 0.443 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.443 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.443 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.443 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2yyu | C5P | Orotidine 5'-phosphate decarboxylase | / | 0.443 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.443 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.443 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3qe0 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.443 | |
| 3w8r | ACP | Uridine kinase | / | 0.443 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.443 | |
| 4au7 | SAH | Histone-lysine N-methyltransferase KMT5C | 2.1.1.43 | 0.443 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.443 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.443 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.443 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.443 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.443 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.443 | |
| 1bcp | ATP | Pertussis toxin subunit 4 | / | 0.442 | |
| 1bcp | ATP | Pertussis toxin subunit 5 | / | 0.442 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1j0d | 5PA | 1-aminocyclopropane-1-carboxylate deaminase | 3.5.99.7 | 0.442 | |
| 1ja0 | NAP | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.442 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.442 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.442 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.442 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.442 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.442 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.442 | |
| 2e16 | SAH | Diphthine synthase | / | 0.442 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2rte | BTN | Streptavidin | / | 0.442 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2x3j | ATP | AcsD | / | 0.442 | |
| 3dzv | ADP | Hydroxyethylthiazole kinase | / | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.442 | |
| 3f10 | 8HG | 8-oxoguanine-DNA-glycosylase | / | 0.442 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.442 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.442 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.442 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.442 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.442 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.442 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.442 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.442 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4e2y | JHZ | Methyltransferase | / | 0.442 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.442 | |
| 4i9h | 1E4 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4img | NGF | N-acetylneuraminate lyase | / | 0.442 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.442 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.442 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.442 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.442 | |
| 5a2y | UTP | Mitochondrial poly(A) polymerase | / | 0.442 | |
| 5cuq | NSC | Genome polyprotein | / | 0.442 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 5jjs | SAH | Genome polyprotein | / | 0.442 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.442 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.441 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.441 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.441 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.441 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.441 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.441 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.441 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.441 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.441 | |
| 2hdn | TAC | Elongation factor Tu 1 | / | 0.441 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.441 | |
| 2imp | NAI | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.441 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2os3 | BB2 | Peptide deformylase | / | 0.441 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.441 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3amf | FMN | FMN-binding protein | / | 0.441 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.441 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.441 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.441 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.441 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4e5l | DBH | Polymerase acidic protein | / | 0.441 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.441 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4j1r | I5R | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4jdc | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.441 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.441 | |
| 4p53 | NAI | 2-epi-5-epi-valiolone synthase | / | 0.441 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.441 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.441 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.441 | |
| 4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.441 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.441 | |
| 5dv2 | C5P | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.441 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.440 | |
| 1kqc | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.440 | |
| 1nb6 | UTP | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 1o6z | NAD | Malate dehydrogenase | / | 0.440 | |
| 1oo6 | SN2 | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.440 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.440 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1ytm | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.440 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.440 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.440 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.440 | |
| 2j4l | UTP | Uridylate kinase | 2.7.4.22 | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.440 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.440 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3a6q | FMN | FMN-binding protein | / | 0.440 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.440 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.440 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.440 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.440 | |
| 3epo | MP5 | Phosphomethylpyrimidine synthase | / | 0.440 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.440 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.440 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.440 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4ctk | SAM | Genome polyprotein | / | 0.440 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.440 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.440 | |
| 4eb3 | 0O3 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.440 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.440 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.440 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.440 | |
| 4idp | GNP | Atlastin-1 | 3.6.5 | 0.440 | |
| 4iij | GTP | Tubulin alpha-1B chain | / | 0.440 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.440 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.440 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.440 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.440 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.440 |