Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4x8lAP5Adenylate kinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4x8lAP5Adenylate kinase/1.000
2rgxAP5Adenylate kinase/0.618
2akyAP5Adenylate kinase/0.612
4jl5ADPAdenylate kinase/0.602
2oo7AP5Adenylate kinase/0.597
4qbiAP5Adenylate kinase/0.593
3dkvAP5Adenylate kinase/0.589
4w5jAP5Adenylate kinase/0.588
4cf7ADPAdenylate kinase/0.583
3hpqAP5Adenylate kinase/0.571
2eckADPAdenylate kinase/0.567
3dl0AP5Adenylate kinase/0.567
1akeAP5Adenylate kinase/0.565
2eu8AP5Adenylate kinase/0.564
4nu0AP5Adenylate kinase/0.562
4jloADPAdenylate kinase/0.559
4jkyADPAdenylate kinase/0.558
2osbAP5Adenylate kinase/0.557
2qajAP5Adenylate kinase/0.557
4jl6ADPAdenylate kinase/0.552
4qbhAP5Adenylate kinase/0.550
1ankANPAdenylate kinase/0.549
1p3jAP5Adenylate kinase/0.549
4jldADPAdenylate kinase/0.548
4x8oAP5Adenylate kinase/0.543
4mkfAP5Adenylate kinase/0.531
4ikeADPAdenylate kinase/0.516
3tlxADPAdenylate kinase 2/0.507
1nzdUPGDNA beta-glucosyltransferase/0.500
1p4aPCPPur operon repressor/0.500
4ai8DZAHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.495
4bb3KKAIsopenicillin N synthase1.21.3.10.494
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.493
2vprTDCTetracycline repressor protein class H/0.488
2iypA2P6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.487
2qo9ANPEphrin type-A receptor 32.7.10.10.487
2x0rNADMalate dehydrogenase/0.487
2ozrGG1Collagenase 33.4.240.486
4kwhNAPReductase homolog/0.485
4yaiNAIC alpha-dehydrogenase/0.485
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.484
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.484
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.483
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.483
3s79ASDAromatase1.14.14.140.483
4xgxADPFAD:protein FMN transferase/0.482
1x1cSAHC-20 methyltransferase/0.480
4xybNDPFormate dehydrogenase/0.480
2py7ATPPhosphoenolpyruvate carboxykinase (ATP)/0.479
1udaUFGUDP-glucose 4-epimerase5.1.3.20.478
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.478
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.478
5iu86DZAdenosine receptor A2a/0.478
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.477
3wb2YGPUncharacterized protein MJ0488/0.477
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.476
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.476
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.476
2x7hPFNProstaglandin reductase 310.475
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.475
3lqfNADGalactitol dehydrogenase/0.475
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.475
4g5dNDPProstaglandin F synthase1.1.1.1880.475
2w71L23Biotin carboxylase6.3.4.140.474
4dptAGSMevalonate diphosphate decarboxylase/0.473
4xj43ATCyclic GMP-AMP synthase/0.473
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.473
1w48APCNTPase P4/0.472
1x7hNDPPutative ketoacyl reductase1.3.10.472
1yp3ATPGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.472
2bueCOAAAC(6')-Ib/0.472
2hu2NADC-terminal binding protein 1/0.472
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
2olrATPPhosphoenolpyruvate carboxykinase (ATP)/0.472
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.472
3ieuGDPGTPase Era/0.472
4avlTMPPolymerase acidic protein/0.472
5kcpNAJAlcohol dehydrogenase E chain1.1.1.10.472
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.471
1esvLARActin, alpha skeletal muscle/0.471
2zvcSAHPrecorrin-3 C17-methyltransferase/0.470
3mvm39PMitogen-activated protein kinase 14/0.470
3t58FADSulfhydryl oxidase 11.8.3.20.470
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.470
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.469
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.469
1n3sGTPGTP cyclohydrolase 13.5.4.160.469
1vftDCSAlanine racemase/0.469
1z7eATPBifunctional polymyxin resistance protein ArnA/0.469
3dmeFADPutative conserved exported protein/0.469
4a7b3W5Collagenase 33.4.240.469
4i02CMPcAMP-activated global transcriptional regulator CRP/0.469
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.469
1bsvNDPGDP-L-fucose synthase/0.468
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
3cvkN34Genome polyprotein2.7.7.480.468
1fdoMGDFormate dehydrogenase H1.1.99.330.467
1h51FMNPentaerythritol tetranitrate reductase/0.467
1wvgCXYCDP-glucose 4,6-dehydratase4.2.1.450.467
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.467
2nnqT4BFatty acid-binding protein, adipocyte/0.467
3cgbCOACoenzyme A disulfide reductase/0.467
3kb6NADD-lactate dehydrogenase/0.467
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.467
4dc0NDPPutative ketoacyl reductase1.3.10.467
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.467
4ure1PSCyclohexanol dehydrogenase/0.467
1cf3FADGlucose oxidase1.1.3.40.466
1nptNADGlyceraldehyde-3-phosphate dehydrogenase/0.466
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.466
4f5dC2EStimulator of interferon genes protein/0.466
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
2hfuMEVMevalonate kinase/0.465
2vnmCM8Beta-secretase 13.4.23.460.465
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.465
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.465
4b1uLABActin, alpha skeletal muscle/0.465
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.465
4txzG2PCyclic GMP-AMP synthase/0.465
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.465
5cdtNAJAlcohol dehydrogenase E chain1.1.1.10.465
1orrCDPCDP-paratose 2-epimerase/0.464
1qtiGNTAcetylcholinesterase3.1.1.70.464
2iviACWIsopenicillin N synthase1.21.3.10.464
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.464
4i0aCMPcAMP-activated global transcriptional regulator CRP/0.464
4loi1YCStimulator of interferon genes protein/0.464
4uofDATNucleoside diphosphate kinase/0.464
4zm3PLPAminotransferase/0.464
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.464
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.463
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.463
2ow9SP6Collagenase 33.4.240.463
3akm11DFatty acid-binding protein, intestinal/0.463
3autNAIGlucose 1-dehydrogenase 41.1.1.470.463
3rbvNAPSugar 3-ketoreductase/0.463
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.463
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.463
4ehyADPTetraacyldisaccharide 4'-kinase/0.463
4fqsLYAThymidylate synthase ThyA/0.463
4yp12BAStimulator of interferon genes protein/0.463
5ifyTRHGlucose-1-phosphate thymidylyltransferase/0.463
1iy8NADLevodione reductase/0.462
2c29NAPDihydroflavonol 4-reductase/0.462
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.462
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.462
3qt62P0Mevalonate diphosphate decarboxylase/0.462
4bfuZVUPantothenate kinase2.7.1.330.462
4d9eLCSD-cysteine desulfhydrase/0.462
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
4weqNAPNAD-dependent dehydrogenase/0.462
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.461
1g4tFTPThiamine-phosphate synthase/0.461
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.461
2vbpVB1Isopenicillin N synthase1.21.3.10.461
2zsiGA4Gibberellin receptor GID1A30.461
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.461
1cjtFOKAdenylate cyclase type 2/0.460
1cjtFOKAdenylate cyclase type 5/0.460
1dljUGAUDP-glucose 6-dehydrogenase/0.460
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.460
1jx2ADPMyosin-2 heavy chain/0.460
1mgoNADAlcohol dehydrogenase E chain1.1.1.10.460
1necFMNOxygen-insensitive NAD(P)H nitroreductase10.460
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.460
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.460
2z95NDPGDP-mannose 4,6-dehydratase/0.460
3bosCDPRegulatory inactivation of DnaA Hda protein/0.460
3d4bDZDNAD-dependent protein deacetylase/0.460
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.460
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.460
5a3bAPRSIR2 family protein/0.460
5im3DTPRibonucleoside-diphosphate reductase/0.460
1cg3IMOAdenylosuccinate synthetase/0.459
1f8fNADBenzyl alcohol dehydrogenase/0.459
2bu9HFVIsopenicillin N synthase1.21.3.10.459
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.459
2jb4A14Isopenicillin N synthase1.21.3.10.459
3nx4NAPPutative oxidoreductase/0.459
3wthIM4Acetylcholine-binding protein/0.459
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.459
4hxyNDPPlm1/0.459
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.459
4o59NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.459
5jtbZMAAdenosine receptor A2a/0.459
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.458
1oc1ASVIsopenicillin N synthase1.21.3.10.458
4jc51K5Stimulator of interferon genes protein/0.458
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.458
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.458
5ftcADPTPR domain protein/0.458
1q43CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.457
1rkxNADCDP-D-glucose-4,6-dehydratase/0.457
1tduCB3Thymidylate synthase/0.457
2vcmM11Isopenicillin N synthase1.21.3.10.457
2yvgNADFerredoxin reductase/0.457
3c6p2S3Protein TRANSPORT INHIBITOR RESPONSE 1/0.457
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.457
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.457
4h6rFDAProline dehydrogenase/0.457
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.457
4tx9AMZPhosphoribosyl isomerase A/0.457
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.457
5jlaNADPutative short-chain dehydrogenase/reductase/0.457
1hkuNADC-terminal-binding protein 11.1.10.456
1jpaANPEphrin type-B receptor 22.7.10.10.456
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.456
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
3iaeD7KBenzaldehyde lyase/0.456
4bfwZVWPantothenate kinase2.7.1.330.456
4gqkADPActin cross-linking toxin VgrG1/0.456
4oztP1AEcdysone receptor, putative/0.456
5idwNAPShort-chain dehydrogenase/reductase SDR/0.456
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.456
5l3rGCPCell division protein FtsY homolog, chloroplastic/0.456
1ooqFMNOxygen-insensitive NAD(P)H nitroreductase/0.455
1pj2NAINAD-dependent malic enzyme, mitochondrial1.1.1.380.455
1yp4ADQGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.455
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.455
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.455
3ik6HCZGlutamate receptor 2/0.455
3jpuTY4Transcriptional activator protein LasR/0.455
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.455
3mpt1GKMitogen-activated protein kinase 14/0.455
3mw9NAIGlutamate dehydrogenase 1, mitochondrial1.4.1.30.455
3oibFDAPutative acyl-CoA dehydrogenase/0.455
4k9dNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.455
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
5uviZMAAdenosine receptor A2a/0.455
1i2lDCSAminodeoxychorismate lyase4.1.3.380.454
1nhrFADNADH peroxidase1.11.1.10.454
1qiqACCIsopenicillin N synthase1.21.3.10.454
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.454
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.454
2x9dITCTetracycline repressor protein class D/0.454
2yutNAPPutative short-chain oxidoreductase/0.454
3c3xNAPEugenol synthase 11.1.1.3180.454
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.454
3s1dZIRCytokinin dehydrogenase 11.5.99.120.454
4dieC5PCytidylate kinase/0.454
4f6w0SSCyclin-dependent kinase 82.7.11.220.454
4k6fNAPPutative Acetoacetyl-CoA reductase/0.454
4ki8ADP60 kDa chaperonin/0.454
1ae1NAPTropinone reductase 1/0.453
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.453
1gky5GPGuanylate kinase2.7.4.80.453
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.453
1ih8APCNH(3)-dependent NAD(+) synthetase6.3.1.50.453
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.453
1tsxUMPThymidylate synthase/0.453
1xs7MMIBeta-secretase 13.4.23.460.453
2q4bNAPUncharacterized protein At5g02240/0.453
2v5aLZLBiotin carboxylase6.3.4.140.453
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.453
2xyuQ9GEphrin type-A receptor 42.7.10.10.453
2y6o1N1Ephrin type-A receptor 42.7.10.10.453
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.453
3cluFADElectron transfer flavoprotein subunit alpha/0.453
3ekuCY9Actin-5C/0.453
3iphG11Mitogen-activated protein kinase 14/0.453
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.453
3w8dNAD3-hydroxybutyrate dehydrogenase/0.453
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4ambDUDPutative glycosyl transferase/0.453
4r7uUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
4rosAPRMalate dehydrogenase/0.453
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.453
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
5d3qGDPDynamin-13.6.5.50.453
1s3uTQDDihydrofolate reductase1.5.1.30.452
1tduDURThymidylate synthase/0.452
1u71MXADihydrofolate reductase1.5.1.30.452
2b7aIZATyrosine-protein kinase JAK2/0.452
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.452
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.452
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.452
3bv2P38Mitogen-activated protein kinase 14/0.452
3he3FADUDP-galactopyranose mutase/0.452
3rv6VAESalicylate synthase/0.452
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.452
4azmT4BFatty acid-binding protein, epidermal/0.452
4i01CMPcAMP-activated global transcriptional regulator CRP/0.452
4kgmATPUncharacterized protein/0.452
4y9qC2EUncharacterized protein/0.452
5cdsNAJAlcohol dehydrogenase E chain1.1.1.10.452
5iqdGNPBifunctional AAC/APH2.3.10.452
1c7oPPGHemolysin/0.451
1do8NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.451
1gpnHUBAcetylcholinesterase3.1.1.70.451
2dknNAI3-alpha-hydroxysteroid dehydrogenase/0.451
2ds11CDCyclin-dependent kinase 22.7.11.220.451
2g1m4HGEgl nine homolog 1/0.451
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.451
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.451
2vbdV10Isopenicillin N synthase1.21.3.10.451
2wzmNA7Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346/0.451
3b1jNADGlyceraldehyde-3-phosphate dehydrogenase/0.451
3pjuC2EDiguanylate cyclase/phosphodiesterase/0.451
3wv9FEGHmd co-occurring protein HcgE/0.451
4cjfRVNIntegrase/0.451
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.451
4g2fC07Ephrin type-A receptor 32.7.10.10.451
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.451
4nu5NADPhosphonate dehydrogenase1.20.1.10.451
4opgFDAConserved Archaeal protein/0.451
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
1fxsNAPGDP-L-fucose synthase/0.450
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.450
1qjfACSIsopenicillin N synthase1.21.3.10.450
1sirNBCGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.450
1udbUFGUDP-glucose 4-epimerase5.1.3.20.450
1udcUFMUDP-glucose 4-epimerase5.1.3.20.450
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.450
1xddAAYIntegrin alpha-L/0.450
1xelUPGUDP-glucose 4-epimerase5.1.3.20.450
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
1zh8NAPUncharacterized protein/0.450
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.450
2pb2PLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.450
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.450
3eon341Glutaryl-CoA dehydrogenase/0.450
3gncQQQGlutaryl-CoA dehydrogenase/0.450
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.450
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.450
4bmvNAPShort-chain dehydrogenase/0.450
1cbqRE9Cellular retinoic acid-binding protein 2/0.449
1dr2TAPDihydrofolate reductase1.5.1.30.449
1hb1OCVIsopenicillin N synthase1.21.3.10.449
1n5dNDPCarbonyl reductase [NADPH] 1/0.449
1q6yCOAFormyl-CoA:oxalate CoA-transferase/0.449
1rfuADPPyridoxal kinase2.7.1.350.449
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2b9yFADPutative aminooxidase/0.449
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.449
2qimZEAClass 10 plant pathogenesis-related protein/0.449
2rg6287Mitogen-activated protein kinase 14/0.449
3cltFADElectron transfer flavoprotein subunit alpha/0.449
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.449
3nzpPLPArginine decarboxylase/0.449
3q3cNADNAD-dependent L-serine dehydrogenase/0.449
3sx2NADUncharacterized protein/0.449
3w6hAZMCarbonic anhydrase 14.2.1.10.449
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
3zhzFM71-deoxy-D-xylulose 5-phosphate reductoisomerase/0.449
4ey6GNTAcetylcholinesterase3.1.1.70.449
4looSB4Mitogen-activated protein kinase 14/0.449
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.449
6cp4CAMCamphor 5-monooxygenase1.14.15.10.449
1bk0ACVIsopenicillin N synthase1.21.3.10.448
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.448
1m78NDPDihydrofolate reductase1.5.1.30.448
1qf4RPDAdenylosuccinate synthetase/0.448
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.448
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
3clsFADElectron transfer flavoprotein subunit alpha/0.448
3flwFLWMitogen-activated protein kinase 14/0.448
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.448
3ocgOCGMitogen-activated protein kinase 14/0.448
3r0iC0K1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.448
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.448
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.448
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
4wouGDPPhosphoenolpyruvate carboxykinase [GTP]/0.448
4xyeNADFormate dehydrogenase/0.448
4yagNAIC alpha-dehydrogenase/0.448
1mg5NAIAlcohol dehydrogenase1.1.1.10.447
1p3dUMAUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.447
1trgCB3Thymidylate synthase/0.447
1u1cBAUUridine phosphorylase2.4.2.30.447
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.447
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2z1mGDPGDP-mannose 4,6-dehydratase/0.447
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.447
3bhtMFRCyclin-dependent kinase 22.7.11.220.447
3fwfCAMCamphor 5-monooxygenase1.14.15.10.447
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.447
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.447
3r9iADPSeptum site-determining protein MinD/0.447
3tlkEB4Ferrienterobactin-binding periplasmic protein/0.447
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
4a99FADTetX family tetracycline inactivation enzyme/0.447
4bqyFNTEgl nine homolog 1/0.447
4l4xNDPAmphI/0.447
4zolGTPTubulin alpha-1B chain/0.447
5fknTDCTetracycline repressor protein class D/0.447
1ftlDNQGlutamate receptor 2/0.446
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.446
1oonFMNOxygen-insensitive NAD(P)H nitroreductase/0.446
1rj9GCPSignal recognition particle receptor FtsY/0.446
1xmvADPProtein RecA/0.446
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.446
1yluFMNOxygen-insensitive NAD(P)H nitroreductase/0.446
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.446
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.446
2bfmTOPPteridine reductase 11.5.1.330.446
2ylxFADPhenylacetone monooxygenase1.14.13.920.446
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.446
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.446
3nh8DC2N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)3.5.1.1140.446
3rypCMPcAMP-activated global transcriptional regulator CRP/0.446
3sf6FDAGlutaryl-CoA dehydrogenase/0.446
4ebfNADPhosphonate dehydrogenase1.20.1.10.446
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.446
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.446
4fxfATPPyruvate kinase PKM2.7.1.400.446
4l9q9TPSerum albumin/0.446
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
4rvgTYDD-mycarose 3-C-methyltransferase/0.446
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.446
5il1SAMN6-adenosine-methyltransferase 70 kDa subunit/0.446
4xnw2IDP2Y purinoceptor 1/0.446
1a72PADAlcohol dehydrogenase E chain1.1.1.10.445
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.445
1snyNAPLD36273p/0.445
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.445
2cbsR13Cellular retinoic acid-binding protein 2/0.445
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.445
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.445
2eixFADNADH-cytochrome b5 reductase/0.445
2pswCOAN-alpha-acetyltransferase 50/0.445
2xpvMIYTetracycline repressor protein class D/0.445
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.445
3dokGWJPol protein/0.445
3e6eDCSAlanine racemase/0.445
3fklFKLMitogen-activated protein kinase 14/0.445
3lpjZ75Beta-secretase 13.4.23.460.445
3mauEXTPutative sphingosine-1-phosphate lyase/0.445
3o0qTTPVitamin B12-dependent ribonucleotide reductase/0.445
3oq6NAJAlcohol dehydrogenase E chain1.1.1.10.445
3p62FMNPentaerythritol tetranitrate reductase/0.445
3rgaILDEpoxide hydrolase LasB5.5.10.445
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.445
4nbwNADShort-chain dehydrogenase/reductase SDR/0.445
4y0kNAPAntE/0.445
4z0hNADGlyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic1.2.1.120.445
5ez4NADBetaine-aldehyde dehydrogenase/0.445
5i4nATPTyrosine-protein kinase JAK2/0.445
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.445
1aztGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.444
1cqp803Integrin alpha-L/0.444
1eyqNARChalcone--flavonone isomerase 15.5.1.60.444
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1j21ATPArgininosuccinate synthase/0.444
1lf3EH5Plasmepsin-23.4.23.390.444
1mzs6693-oxoacyl-[acyl-carrier-protein] synthase 3/0.444
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.444
1rkdADPRibokinase/0.444
1u4dDBQActivated CDC42 kinase 1/0.444
2aa0MTPAdenosine kinase2.7.1.200.444
2fhnBNIAvidin-related protein 4/5/0.444
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.444
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.444
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.444
2rlcCHDCholoylglycine hydrolase3.5.1.240.444
3ed1GA3Gibberellin receptor GID1/0.444
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.444
3nxxNDPDihydrofolate reductase1.5.1.30.444
3pjtC2EDiguanylate cyclase/phosphodiesterase/0.444
3tfyCOAN-alpha-acetyltransferase 502.3.10.444
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.444
4eiqKCTPutative FAD-monooxygenase/0.444
4eiyZMAAdenosine receptor A2a/0.444
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.444
4phlPILPhosphodiesterase/0.444
4qaiFMNNADPH dehydrogenase/0.444
4wucANPDNA gyrase subunit B/0.444
5dbyNPSSerum albumin/0.444
5ig2NADShort-chain dehydrogenase/reductase SDR/0.444
5iua6DXAdenosine receptor A2a/0.444
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.443
1adfTADAlcohol dehydrogenase E chain1.1.1.10.443
1drhNAPDihydrofolate reductase1.5.1.30.443
1m9aGTXGlutathione S-transferase class-mu 26 kDa isozyme2.5.1.180.443
1pt5ACOFormyl-CoA:oxalate CoA-transferase/0.443
1rszDIHPurine nucleoside phosphorylase2.4.2.10.443
1t2cNAIL-lactate dehydrogenase1.1.1.270.443
1uyuCAMCamphor 5-monooxygenase1.14.15.10.443
1yonA2R2-dehydropantoate 2-reductase1.1.1.1690.443
2bkzSBCCyclin-dependent kinase 22.7.11.220.443
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.443
2g1s4IGRenin3.4.23.150.443
2g8yNADHydroxycarboxylate dehydrogenase B/0.443
2omeNADC-terminal-binding protein 2/0.443
2qqfA1RNAD-dependent protein deacetylase HST23.5.10.443
2vn0TDZCytochrome P450 2C8/0.443
2vnaNAPProstaglandin reductase 21.3.1.480.443
2xb5I7TTetracycline repressor protein class D/0.443
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.443
3a292T0Fructose-1,6-bisphosphatase 13.1.3.110.443
3aw9NADNAD-dependent epimerase/dehydratase/0.443
3eej53RUncharacterized protein/0.443
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.443
3vmmP0DAlanine--anticapsin ligase/0.443
3w8fNAD3-hydroxybutyrate dehydrogenase/0.443
3wtiCT4Acetylcholine-binding protein/0.443
4an4DUDPutative glycosyl transferase/0.443
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.443
4eqxFADCoenzyme A disulfide reductase/0.443
4kp8E1GCarbonic anhydrase 124.2.1.10.443
4pzkSAHPutative tRNA (cytidine(34)-2'-O)-methyltransferase/0.443
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.443
1eq2NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.442
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.442
1fm1WAYCollagenase 33.4.240.442
1iyzNDPProbable quinone oxidoreductase/0.442
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.442
1svmATPLarge T antigen3.6.40.442
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.442
2fnaADPUncharacterized protein/0.442
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.442
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.442
2wghDTPRibonucleoside-diphosphate reductase large subunit1.17.4.10.442
2y05NAPProstaglandin reductase 1/0.442
3imgBZ2Pantothenate synthetase6.3.2.10.442
3k7mFAD6-hydroxy-L-nicotine oxidase/0.442
3ms421NGlycogen phosphorylase, muscle form2.4.1.10.442
3nmpPYVAbscisic acid receptor PYL2/0.442
3qvsNADMyo-inositol-1-phosphate synthase (Ino1)/0.442
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.442
3rbqGLY_ALA_GLY_DAOProtein unc-119 homolog A/0.442
3w8rACPUridine kinase/0.442
4b5dSW4Achbp/0.442
4gevCB3Thymidylate synthase/0.442
4j7xNAPSepiapterin reductase1.1.1.1530.442
4kgkGTPUncharacterized protein/0.442
4mv8ACPBiotin carboxylase6.3.4.140.442
4rqzVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.442
1cgpCMPcAMP-activated global transcriptional regulator CRP/0.441
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.441
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.441
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.441
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.441
1n7hGDPGDP-mannose 4,6 dehydratase 24.2.1.470.441
1naiNADUDP-glucose 4-epimerase5.1.3.20.441
1rx1NAPDihydrofolate reductase1.5.1.30.441
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.441
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.441
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.441
1xq6NAPUncharacterized protein At5g02240/0.441
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.441
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.441
2iko7IGRenin3.4.23.150.441
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.441
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2qocANPEphrin type-A receptor 32.7.10.10.441
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
2rr1W8RGenome polyprotein/0.441
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
2zbaZBATrichothecene 3-O-acetyltransferase/0.441
2zcvNDPQuinone oxidoreductase 21.6.5.20.441
3aw9GDUNAD-dependent epimerase/dehydratase/0.441
3cukFADD-amino-acid oxidase1.4.3.30.441
3cvyFADRE11660p/0.441
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3frqERYErythromycin resistance repressor protein/0.441
3fwgCAMCamphor 5-monooxygenase1.14.15.10.441
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.441
3hyoADPPyridoxal kinase/0.441
3kccCMPcAMP-activated global transcriptional regulator CRP/0.441
3lfzADPUncharacterized protein MJ1225/0.441
3pm9FADPutative oxidoreductase/0.441
3sxpNADADP-L-glycero-D-mannoheptose-6-epimerase/0.441
3to3ATPPetrobactin biosynthesis protein AsbB/0.441
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.441
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.441
4eepFMNPhototropin-22.7.11.10.441
4eomATPCyclin-dependent kinase 22.7.11.220.441
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.441
4irnFADAnaB/0.441
4u8iFDAUDP-galactopyranose mutase/0.441
4y8vADPAcyl-CoA synthetase (NDP forming)/0.441
5bylGCPBifunctional AAC/APH2.3.10.441
5kj1NAJAlcohol dehydrogenase E chain1.1.1.10.441
1cg0IMOAdenylosuccinate synthetase/0.440
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
1gvhFADFlavohemoprotein/0.440
1ia1NDPDihydrofolate reductase1.5.1.30.440
1rpnNDPGDP-mannose 4,6-dehydratase/0.440
1tojHCIAspartate aminotransferase2.6.1.10.440
1ybmNAPUncharacterized protein At5g02240/0.440
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.440
2tohHBITyrosine 3-monooxygenase1.14.16.20.440
2xf3J01Uncharacterized protein/0.440
2xtnGTPGTPase IMAP family member 2/0.440
3d84NDPDihydrofolate reductase1.5.1.30.440
3drcMTXDihydrofolate reductase1.5.1.30.440
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3jv7NADSecondary alcohol dehydrogenase/0.440
3r3sNADPutative oxidoreductase/0.440
3vqrFADPutative oxidoreductase/0.440
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
3zeiAWHO-acetylserine sulfhydrylase/0.440
4hdhATPGenome polyprotein2.7.7.480.440
4o0lNDPNADPH-dependent 3-quinuclidinone reductase/0.440
4qysPLRTryptophan synthase beta chain 24.2.1.200.440
4rvnCOAPhenylacetate-coenzyme A ligase/0.440
4s1hADPPyridoxal kinase, putative/0.440
4u7wNDPMxaA/0.440
4xmxBESAminopeptidase N3.4.11.20.440
5jqgGTPTubulin alpha-1B chain/0.440
4mqt2CUMuscarinic acetylcholine receptor M2/0.440