Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.237

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2371.000
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.668
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.636
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.601
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.588
3oadLPORenin3.4.23.150.464
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.444
3k1wBFXRenin3.4.23.150.443
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.442
4j7gTRHPCZA361.3/0.442
4yal2AMNADPH--cytochrome P450 reductase/0.441