sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4x24 | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4x24 | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 1.000 | |
| 3eei | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.642 | |
| 1zos | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.635 | |
| 1y6q | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.612 | |
| 1y6r | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.604 | |
| 4wkb | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.598 | |
| 3dp9 | BIG | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.595 | |
| 4bmz | MTA | Aminodeoxyfutalosine nucleosidase | / | 0.548 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.536 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.515 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.510 | |
| 3arv | SAU | Chitinase A | / | 0.508 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.504 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.503 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.500 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.500 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.499 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.496 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.493 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.493 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.492 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.492 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.491 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.491 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.490 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.490 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.490 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.488 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.488 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.487 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.486 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.486 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.486 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.485 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.485 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.485 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.484 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.484 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.484 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.484 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.483 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.483 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.483 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.483 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.483 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.483 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.483 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.482 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.482 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.482 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.482 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.482 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.481 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.481 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.481 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.481 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.480 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.480 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.480 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.479 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.479 | |
| 1mbz | IOT | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.478 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.478 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.477 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.477 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.477 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 1swt | BTN | Streptavidin | / | 0.476 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.476 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.476 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.476 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.476 | |
| 3cwk | REA | Cellular retinoic acid-binding protein 2 | / | 0.476 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.476 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.476 | |
| 4phl | PIL | Phosphodiesterase | / | 0.476 | |
| 5fuw | THM | Thymidine kinase, putative | / | 0.476 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.476 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.475 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.475 | |
| 4pzt | SOP | Histone acetyltransferase p300 | / | 0.475 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.474 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.474 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.474 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.474 | |
| 2x2r | ADP | Kinesin-like protein KIF11 | / | 0.474 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.474 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.474 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.474 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 1zp4 | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.473 | |
| 3rin | I2O | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 4nbl | 2J6 | Caspase-6 | 3.4.22.59 | 0.473 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.472 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 2mjp | ANP | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.472 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.472 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.472 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.472 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 3rix | 923 | Luciferin 4-monooxygenase | 1.13.12.7 | 0.472 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.472 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.472 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.472 | |
| 4fps | 0UX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.472 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.472 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.471 | |
| 3qh2 | 3NM | Thiazole tautomerase | / | 0.471 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.471 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.471 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.471 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.470 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.470 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.470 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.470 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.470 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.470 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.469 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.469 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.469 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.469 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.469 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3hvk | 719 | Catechol O-methyltransferase | 2.1.1.6 | 0.469 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.469 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.469 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.469 | |
| 4y6n | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.469 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.468 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.468 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.468 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.468 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.468 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.468 | |
| 3v4t | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.468 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.468 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.468 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.468 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.467 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.467 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.467 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.467 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.467 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.467 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.467 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4eh2 | IRG | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.467 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.467 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.467 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3jqg | AX6 | Pteridine reductase, putative | / | 0.466 | |
| 3zrr | PXG | Serine-pyruvate aminotransferase (AgxT) | / | 0.466 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.466 | |
| 4ykl | GMP | Aprataxin-like protein | 3 | 0.466 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.465 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.465 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.465 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 3htj | ET | EbrA repressor | / | 0.465 | |
| 3qp8 | HL0 | Transcriptional activator, LuxR/UhpA family of regulators | / | 0.465 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.465 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.465 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.465 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.464 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.464 | |
| 2c92 | TP6 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.464 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.464 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.464 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.464 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.463 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.463 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 3up3 | XCA | aceDAF-12 | / | 0.463 | |
| 3vo3 | 0KF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.463 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.463 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.463 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.463 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.463 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.463 | |
| 1b48 | HAG | Glutathione S-transferase A4 | 2.5.1.18 | 0.462 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.462 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.462 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.462 | |
| 2pda | TPP | Pyruvate synthase | / | 0.462 | |
| 3bhr | THG | Thymidylate synthase | / | 0.462 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.462 | |
| 4n1g | CEI | Obelin | / | 0.462 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.461 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.461 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.461 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.461 | |
| 3ndj | JHZ | Methyltransferase | / | 0.461 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.461 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.461 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.461 | |
| 3up0 | D7S | aceDAF-12 | / | 0.461 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.461 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.461 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.460 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.460 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.460 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.460 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.460 | |
| 2uza | HTL | Pyruvate synthase | / | 0.460 | |
| 3hqd | ANP | Kinesin-like protein KIF11 | / | 0.460 | |
| 3nwb | 659 | Catechol O-methyltransferase | 2.1.1.6 | 0.460 | |
| 3tl1 | JRO | Putative polyketide cyclase | / | 0.460 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.460 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.460 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.459 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.459 | |
| 2r8p | T6F | Transketolase 1 | / | 0.459 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.459 | |
| 3uq6 | ADN | Putative adenosine kinase | / | 0.459 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.459 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.459 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.459 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.459 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.459 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.459 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.459 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.459 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.459 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.458 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.458 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.458 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.458 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.458 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.458 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.458 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.458 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.458 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.458 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.458 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.458 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.458 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.457 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.457 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.457 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.457 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3ar6 | 12D | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.457 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.457 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.457 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.457 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.457 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.457 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.457 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.457 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.456 | |
| 1ye6 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.456 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.456 | |
| 3bx5 | 304 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.456 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 3mcy | ZH1 | FimH | / | 0.456 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.456 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.455 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.455 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.455 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.455 | |
| 1srf | MTB | Streptavidin | / | 0.455 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.455 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 1zdw | FLV | Prenyltransferase | / | 0.455 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.455 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.455 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.455 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3w5u | FAD | Ferredoxin | / | 0.455 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.455 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.455 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.455 | |
| 4h7z | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.455 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.455 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.455 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.455 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.454 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.454 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.454 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.454 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.454 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.454 | |
| 3vaq | ADN | Putative adenosine kinase | / | 0.454 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.454 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.454 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.454 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.454 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.454 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.454 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.453 | |
| 1jje | BYS | Beta-lactamase | / | 0.453 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.453 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.453 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.453 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.453 | |
| 3fbu | COA | Acetyltransferase, GNAT family | / | 0.453 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.453 | |
| 3kud | GDP | GTPase HRas | / | 0.453 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.453 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.453 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.453 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.453 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.452 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.452 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.452 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.452 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.452 | |
| 1wnz | 2VA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.452 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.452 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.452 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.452 | |
| 3tpt | ADP | Serine/threonine-protein kinase toxin HipA | / | 0.452 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 4hne | ADP | Phosphatidylinositol 4-kinase type 2-alpha | / | 0.452 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4kzl | 20D | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 4qi9 | MTX | Dihydrofolate reductase | / | 0.452 | |
| 4r7u | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.452 | |
| 4y1b | NAP | AntE | / | 0.452 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 1t48 | BB3 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.451 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.451 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2fai | 459 | Estrogen receptor | / | 0.451 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.451 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 2xvw | 9NR | Serum albumin | / | 0.451 | |
| 3lth | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.451 | |
| 4asj | N6A | Glucose-1-phosphate thymidylyltransferase | / | 0.451 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.451 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.451 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.451 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.451 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.450 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.450 | |
| 1ltz | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.450 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.450 | |
| 1sre | HAB | Streptavidin | / | 0.450 | |
| 1stp | BTN | Streptavidin | / | 0.450 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.450 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.450 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.450 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 4la0 | 198 | Serum albumin | / | 0.450 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.450 | |
| 5dst | SAH | Protein arginine N-methyltransferase 8 | 2.1.1 | 0.450 | |
| 1o1v | TCH | Gastrotropin | / | 0.449 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.449 | |
| 1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.449 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.449 | |
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.449 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.449 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.449 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.449 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 2r2g | EMF | Eugenol synthase 1 | 1.1.1.318 | 0.449 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.449 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2yat | EEU | Estrogen receptor | / | 0.449 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.449 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.449 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3ufg | ATP | Glycine--tRNA ligase alpha subunit | / | 0.449 | |
| 3vc2 | SAH | Geranyl diphosphate 2-C-methyltransferase | 2.1.1.255 | 0.449 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.449 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.449 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.449 | |
| 4c1f | X8Z | Metallo-beta-lactamase type 2 | / | 0.449 | |
| 4hdr | DMD | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | / | 0.449 | |
| 4hdr | DMD | ArsB | / | 0.449 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.449 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.449 | |
| 4zth | GG5 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 5fuv | THM | Thymidine kinase, putative | / | 0.449 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.449 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1pua | COA | HAT A1 | / | 0.448 | |
| 1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.448 | |
| 1rt2 | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.448 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2r8o | T5X | Transketolase 1 | / | 0.448 | |
| 3abi | NAD | Uncharacterized protein | / | 0.448 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.448 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.448 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 3oxk | 5GP | Histidine triad nucleotide-binding protein | 3 | 0.448 | |
| 3v4e | COA | Putative acetyltransferase SACOL2570 | 2.3.1 | 0.448 | |
| 4buf | F36 | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.448 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.448 | |
| 4m37 | SAH | Protein arginine N-methyltransferase 7 | 2.1.1 | 0.448 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.448 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.448 | |
| 1a2n | TET | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1kdm | DHT | Sex hormone-binding globulin | / | 0.447 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.447 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.447 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.447 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.447 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.447 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.447 | |
| 3kqj | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.447 | |
| 3vas | ADN | Putative adenosine kinase | / | 0.447 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.447 | |
| 4d9f | DCS | D-cysteine desulfhydrase | / | 0.447 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.447 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.447 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.447 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.446 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.446 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.446 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.446 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 1w7k | ADP | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.446 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.446 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.446 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.446 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.446 | |
| 3hng | 8ST | Vascular endothelial growth factor receptor 1 | 2.7.10.1 | 0.446 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.446 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.446 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.446 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.446 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4boe | CLR | Japanin | / | 0.446 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 4hl5 | 15W | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.446 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4y0k | NAP | AntE | / | 0.446 | |
| 4y9x | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.446 | |
| 4ykf | NAI | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.446 | |
| 4zoh | MCN | Putative oxidoreductase molybdopterin-binding subunit | / | 0.446 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.446 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.445 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.445 | |
| 1mep | BTN | Streptavidin | / | 0.445 | |
| 1n0h | CIE | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1rxh | BNI | Streptavidin | / | 0.445 | |
| 1sri | DMB | Streptavidin | / | 0.445 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.445 | |
| 1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.445 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.445 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 3cgy | RDC | Virulence sensor histidine kinase PhoQ | 2.7.13.3 | 0.445 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.445 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.445 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3ebi | BEY | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.445 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.445 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.445 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.445 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.445 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.445 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 4ifv | FMQ | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 4lb2 | DM5 | Serum albumin | / | 0.445 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4nyi | GNP | GTPase HRas | / | 0.445 | |
| 4qoh | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.444 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.444 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 1mp4 | UPG | Glucose-1-phosphate thymidylyltransferase | / | 0.444 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 1prc | UQ1 | Reaction center protein L chain | / | 0.444 | |
| 1s36 | CEI | Obelin | / | 0.444 | |
| 1u1j | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 | 2.1.1.14 | 0.444 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.444 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
| 2iut | AGS | DNA translocase FtsK | / | 0.444 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3myk | ANP | Myosin-2 heavy chain | / | 0.444 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
| 3p9t | TCL | Repressor | / | 0.444 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3wzn | BTN | Streptavidin | / | 0.444 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4buw | F33 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.444 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.444 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.444 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.443 | |
| 1c7f | FMN | Flavodoxin | / | 0.443 | |
| 1e79 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1e79 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.443 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.443 | |
| 1klm | SPP | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.443 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.443 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1s7n | COA | Acetyl transferase | / | 0.443 | |
| 2d32 | ANP | Glutamate--cysteine ligase | 6.3.2.2 | 0.443 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.443 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.443 | |
| 2izf | BTN | Streptavidin | / | 0.443 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.443 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.443 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.443 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.443 | |
| 3stx | BKA | Methylketone synthase I | / | 0.443 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.443 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4dko | 0LM | Envelope glycoprotein gp160 | / | 0.443 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.443 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.443 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4l43 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4qrc | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.443 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.443 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.443 | |
| 4phu | 2YB | Free fatty acid receptor 1 | / | 0.443 | |
| 1av5 | AP2 | Histidine triad nucleotide-binding protein 1 | 3 | 0.442 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.442 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.442 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.442 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.442 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.442 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.442 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.442 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.442 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.442 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.442 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3iej | 599 | Cathepsin S | 3.4.22.27 | 0.442 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4bix | ADP | Sensor histidine kinase CpxA | / | 0.442 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.442 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4o7u | THF | Thymidylate synthase | / | 0.442 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.442 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.442 | |
| 4x3q | SAH | SibL | / | 0.442 | |
| 5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.442 | |
| 1ah4 | NAP | Aldose reductase | 1.1.1.21 | 0.441 | |
| 1eqb | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.441 | |
| 1h5s | TMP | Glucose-1-phosphate thymidylyltransferase 1 | / | 0.441 | |
| 1k6m | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 | 2.7.1.105 | 0.441 | |
| 1nbu | PH2 | Dihydroneopterin aldolase | / | 0.441 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.441 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.441 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 1swe | BTN | Streptavidin | / | 0.441 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.441 | |
| 2yhu | WHF | Pteridine reductase | / | 0.441 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.441 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.441 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3gb4 | D3M | DdmC | / | 0.441 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.441 | |
| 3qpv | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.441 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.441 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.441 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.441 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4nbn | 2J7 | Caspase-6 | 3.4.22.59 | 0.441 | |
| 4ug5 | XFK | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.441 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.441 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.441 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1el4 | CTZ | Obelin | / | 0.440 | |
| 1hwl | ADP | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.440 | |
| 1lrm | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.440 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.440 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.440 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.440 | |
| 2cul | FAD | GidA-related protein | / | 0.440 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.440 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2r1n | EPL | Phosphotriesterase | / | 0.440 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.440 | |
| 2wpw | ACO | Orf14 | / | 0.440 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.440 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 | |
| 3gya | COA | GCN5-related N-acetyltransferase | / | 0.440 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.440 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4b6s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 4bud | 29F | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.440 | |
| 4eh3 | IRG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.440 | |
| 4go2 | TAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.440 | |
| 4hvs | 647 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.440 | |
| 4lv8 | ADP | Rhoptry protein 5 C | / | 0.440 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.440 | |
| 4ys0 | ADP | Protein translocase subunit SecA | / | 0.440 |