Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4wevSUZAldo-keto reductase family 1 member B101.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4wevSUZAldo-keto reductase family 1 member B101.1.11.000
5liu388Aldo-keto reductase family 1 member B101.1.10.596
1zuaTOLAldo-keto reductase family 1 member B101.1.10.529
2pdlTOLAldose reductase1.1.1.210.524
2fzdTOLAldose reductase1.1.1.210.510
1ah3TOLAldose reductase1.1.1.210.502
2fzbTOLAldose reductase1.1.1.210.484
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.448
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.446
1ry0PG2Aldo-keto reductase family 1 member C3/0.444
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
4fam0SZAldo-keto reductase family 1 member C3/0.443
3zkuHCVIsopenicillin N synthase1.21.3.10.441
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.440