Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4uthFMNXenobiotic reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4uthFMNXenobiotic reductase/1.000
3l5lFMNXenobiotic reductase/0.802
3n14FMNXenobiotic reductase/0.693
3l67FMNXenobiotic reductase/0.652
2h8xFMNXenA/0.592
1icqFMN12-oxophytodienoate reductase 11.3.1.420.531
1z44FMNNADPH dehydrogenase/0.528
3hf3FMNChromate reductase/0.526
4utlFNRXenobiotic reductase/0.521
3p74FMNPentaerythritol tetranitrate reductase/0.517
3p67FMNPentaerythritol tetranitrate reductase/0.514
3f03FMNPentaerythritol tetranitrate reductase/0.509
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.509
3p62FMNPentaerythritol tetranitrate reductase/0.501
1vyrFMNPentaerythritol tetranitrate reductase/0.500
4tmbFMNOld yellow enzyme/0.487
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.485
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.483
1icsFMN12-oxophytodienoate reductase 11.3.1.420.481
3n19FNRXenobiotic reductase/0.476
3p84FMNPentaerythritol tetranitrate reductase/0.476
1h51FMNPentaerythritol tetranitrate reductase/0.474
1icpFMN12-oxophytodienoate reductase 11.3.1.420.472
3p8jFMNPentaerythritol tetranitrate reductase/0.472
1h63FMNPentaerythritol tetranitrate reductase/0.468
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.467
2abbFMNPentaerythritol tetranitrate reductase/0.467
5fd8A5APutative carboxypeptidase yocD/0.467
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.466
4df2FMNNADPH dehydrogenase/0.465
4utkFNRXenobiotic reductase/0.464
3p8iFMNPentaerythritol tetranitrate reductase/0.460
4qnwFMNChanoclavine-I aldehyde reductase easA/0.459
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.458
1z41FMNNADPH dehydrogenase/0.457
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.457
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.456
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.454
2zsaADPPantothenate kinase2.7.1.330.454
1h50FMNPentaerythritol tetranitrate reductase/0.452
3p82FMNPentaerythritol tetranitrate reductase/0.452
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.452
4rnuFMNNADPH dehydrogenase 11.6.99.10.452
4rnvFMNNADPH dehydrogenase 11.6.99.10.452
1q45FMN12-oxophytodienoate reductase 31.3.1.420.450
1bwlFMNNADPH dehydrogenase 11.6.99.10.448
4tmcFMNOld yellow enzyme/0.448
1oyaFMNNADPH dehydrogenase 11.6.99.10.446
1oycFMNNADPH dehydrogenase 11.6.99.10.445
4acuQN7Beta-secretase 13.4.23.460.445
4lutDCSAlanine racemase/0.445
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.443
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
1bwkFMNNADPH dehydrogenase 11.6.99.10.441
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
4rnwFMNNADPH dehydrogenase 11.6.99.10.441