sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4um1 | 09P | Acetylcholine-binding protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4um1 | 09P | Acetylcholine-binding protein | / | 1.000 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.521 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.511 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.509 | |
| 4afh | L0B | Achbp | / | 0.503 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.502 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.501 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.497 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.496 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.496 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.494 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.494 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.488 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.488 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.486 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.484 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.484 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.482 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.482 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.481 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.481 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.481 | |
| 4b5d | SW4 | Achbp | / | 0.481 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.478 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.478 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.478 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.478 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.477 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.476 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.475 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.475 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.474 | |
| 3u8n | 09S | Acetylcholine-binding protein | / | 0.473 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.472 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.471 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.471 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.470 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.469 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 3wag | TYD | Glycosyltransferase | / | 0.469 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.469 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.467 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.466 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.466 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.465 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.465 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.464 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.464 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.464 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.464 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.464 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.463 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.463 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.463 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.462 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.462 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.460 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.460 | |
| 3fpd | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.460 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.460 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.460 | |
| 4afg | QMR | Achbp | / | 0.460 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.460 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.459 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.459 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.459 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.459 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.459 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.459 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.459 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.458 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.458 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.458 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.458 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.457 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.457 | |
| 1pl1 | ABY | Glutathione S-transferase A1 | 2.5.1.18 | 0.457 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.457 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.457 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.457 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.457 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.457 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.457 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.456 | |
| 2xyd | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.456 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.456 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.456 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.455 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.455 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.455 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.455 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4jic | FMN | GTN Reductase | / | 0.455 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.454 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.454 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.453 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.453 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.453 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.453 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.453 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.452 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.452 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.452 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.452 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.452 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.452 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.452 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.452 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.452 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2rfi | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.451 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.451 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.451 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.450 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.450 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.450 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.450 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.450 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.449 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.449 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.449 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.449 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.449 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.449 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.449 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.449 | |
| 1c7o | PPG | Hemolysin | / | 0.448 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.448 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.448 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.447 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.447 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.447 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.446 | |
| 1kqb | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.446 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.446 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.446 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.445 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.445 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.445 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.445 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.445 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.445 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.445 | |
| 4krs | 1SX | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.445 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3eku | CY9 | Actin-5C | / | 0.444 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.444 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.444 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 2igq | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.443 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.443 | |
| 3wie | DN4 | Glucose 1-dehydrogenase | / | 0.443 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.443 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.443 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.443 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
| 4xwt | U5P | Ribonuclease J | / | 0.443 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.442 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.442 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.442 | |
| 3kmt | SAH | Histone H3K27 methylase | / | 0.442 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.442 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.442 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.442 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.442 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.441 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.441 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.441 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.441 | |
| 3v2u | ATP | Protein GAL3 | / | 0.441 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.441 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.441 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.440 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.440 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.440 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.440 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.440 | |
| 3pft | FMN | Flavin reductase | / | 0.440 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.440 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.440 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.440 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.440 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.440 | |
| 3ny9 | JSZ | Beta-2 adrenergic receptor | / | 0.440 |