scPDB - Distribution of Binding site Similarity values of 4ug9 entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4ug9	1EW	Nitric oxide synthase oxygenase	1.14.13.165

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4ug9	1EW	Nitric oxide synthase oxygenase	1.14.13.165	1.000
4lwa	Q13	Nitric oxide synthase oxygenase	1.14.13.165	0.637
4ug7	1EV	Nitric oxide synthase oxygenase	1.14.13.165	0.616
4ug5	XFK	Nitric oxide synthase oxygenase	1.14.13.165	0.612
1zzr	DP9	Nitric oxide synthase, brain	1.14.13.39	0.571
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.571
4uga	Q05	Nitric oxide synthase oxygenase	1.14.13.165	0.561
2hx4	4HX	Nitric oxide synthase, brain	1.14.13.39	0.547
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.543
1p6j	DP9	Nitric oxide synthase, brain	1.14.13.39	0.542
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.542
4fvz	4KJ	Nitric oxide synthase, brain	1.14.13.39	0.542
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.542
3e7t	B14	Nitric oxide synthase, inducible	1.14.13.39	0.541
3jws	JI4	Nitric oxide synthase, brain	1.14.13.39	0.539
3dqr	JI2	Nitric oxide synthase, brain	1.14.13.39	0.536
3nnz	59W	Nitric oxide synthase, brain	1.14.13.39	0.536
3jwu	J11	Nitric oxide synthase, brain	1.14.13.39	0.531
3b3p	JI7	Nitric oxide synthase, brain	1.14.13.39	0.530
3jwt	JI5	Nitric oxide synthase, brain	1.14.13.39	0.529
4lwb	QJ8	Nitric oxide synthase oxygenase	1.14.13.165	0.529
3ufo	HW4	Nitric oxide synthase, brain	1.14.13.39	0.527
3b3o	JI3	Nitric oxide synthase, brain	1.14.13.39	0.520
3e6t	1A2	Nitric oxide synthase, inducible	1.14.13.39	0.520
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.520
3jx2	JI4	Nitric oxide synthase, brain	1.14.13.39	0.519
3nlp	JSS	Nitric oxide synthase, brain	1.14.13.39	0.519
3png	8CX	Nitric oxide synthase, brain	1.14.13.39	0.519
4jsh	Q15	Nitric oxide synthase, brain	1.14.13.39	0.518
3tym	08R	Nitric oxide synthase, brain	1.14.13.39	0.517
3rqj	Y2B	Nitric oxide synthase, brain	1.14.13.39	0.516
1zzu	DP1	Nitric oxide synthase, brain	1.14.13.39	0.515
4cx5	HW8	Nitric oxide synthase, brain	1.14.13.39	0.515
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39	0.515
3jx0	JI4	Nitric oxide synthase, brain	1.14.13.39	0.513
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.513
3jx4	J11	Nitric oxide synthase, brain	1.14.13.39	0.511
3nlw	3XF	Nitric oxide synthase, brain	1.14.13.39	0.511
3ufv	HW9	Nitric oxide synthase, brain	1.14.13.39	0.511
3ebf	332	Nitric oxide synthase, inducible	1.14.13.39	0.510
3nlr	JRS	Nitric oxide synthase, brain	1.14.13.39	0.510
4k5f	Q14	Nitric oxide synthase, brain	1.14.13.39	0.510
3tyl	AXW	Nitric oxide synthase, brain	1.14.13.39	0.509
1zzq	DP9	Nitric oxide synthase, brain	1.14.13.39	0.507
3jx6	JI5	Nitric oxide synthase, brain	1.14.13.39	0.507
3ufq	HW5	Nitric oxide synthase, brain	1.14.13.39	0.507
4k5e	1Q7	Nitric oxide synthase, brain	1.14.13.39	0.506
3nlv	3XA	Nitric oxide synthase, brain	1.14.13.39	0.505
3e6o	A55	Nitric oxide synthase, inducible	1.14.13.39	0.502
3n62	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.501
3nlj	JRR	Nitric oxide synthase, brain	1.14.13.39	0.501
3eah	327	Nitric oxide synthase, endothelial	1.14.13.39	0.500
3jx3	JI5	Nitric oxide synthase, brain	1.14.13.39	0.500
3nln	JRS	Nitric oxide synthase, brain	1.14.13.39	0.500
4gqe	6KJ	Nitric oxide synthase, brain	1.14.13.39	0.500
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	0.498
3n5y	XFL	Nitric oxide synthase, brain	1.14.13.39	0.498
3e68	AT6	Nitric oxide synthase, inducible	1.14.13.39	0.496
3nlk	JSS	Nitric oxide synthase, brain	1.14.13.39	0.496
4imw	1EV	Nitric oxide synthase, brain	1.14.13.39	0.496
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.495
4jsj	QJ7	Nitric oxide synthase, brain	1.14.13.39	0.495
4k5d	1Q6	Nitric oxide synthase, brain	1.14.13.39	0.495
1r35	I58	Nitric oxide synthase, inducible	1.14.13.39	0.494
3nlo	JSR	Nitric oxide synthase, brain	1.14.13.39	0.493
3ufr	H5W	Nitric oxide synthase, brain	1.14.13.39	0.491
3nlq	JRR	Nitric oxide synthase, brain	1.14.13.39	0.490
3jx5	J14	Nitric oxide synthase, brain	1.14.13.39	0.489
1vaf	ARR	Nitric oxide synthase, inducible	1.14.13.39	0.488
3n5z	XFM	Nitric oxide synthase, brain	1.14.13.39	0.488
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.488
3eai	328	Nitric oxide synthase, inducible	1.14.13.39	0.487
4fw0	5KJ	Nitric oxide synthase, brain	1.14.13.39	0.487
3pnf	8BX	Nitric oxide synthase, brain	1.14.13.39	0.484
3ufp	H4W	Nitric oxide synthase, brain	1.14.13.39	0.484
1qw5	14W	Nitric oxide synthase, inducible	1.14.13.39	0.482
3ufu	HW8	Nitric oxide synthase, brain	1.14.13.39	0.480
4imt	1EW	Nitric oxide synthase, brain	1.14.13.39	0.480
3ufw	HW0	Nitric oxide synthase, brain	1.14.13.39	0.479
4jsi	Q05	Nitric oxide synthase, brain	1.14.13.39	0.479
3e7m	AT2	Nitric oxide synthase, inducible	1.14.13.39	0.478
3svq	JK4	Nitric oxide synthase, brain	1.14.13.39	0.476
4cx3	HW8	Nitric oxide synthase, brain	1.14.13.39	0.475
4k5g	Q13	Nitric oxide synthase, brain	1.14.13.39	0.475
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39	0.473
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.472
3nny	59R	Nitric oxide synthase, brain	1.14.13.39	0.472
3e7g	AT2	Nitric oxide synthase, inducible	1.14.13.39	0.471
3n5v	XFH	Nitric oxide synthase, brain	1.14.13.39	0.469
4jsg	Q10	Nitric oxide synthase, brain	1.14.13.39	0.469
1rs6	DP2	Nitric oxide synthase, brain	1.14.13.39	0.466
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.464
3rqm	X2E	Nitric oxide synthase, brain	1.14.13.39	0.463
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.461
3nlz	3XD	Nitric oxide synthase, brain	1.14.13.39	0.460
3e7i	B2	Nitric oxide synthase, inducible	1.14.13.39	0.457
4jse	QJ2	Nitric oxide synthase, brain	1.14.13.39	0.457
1m9k	7NI	Nitric oxide synthase, endothelial	1.14.13.39	0.450
4imu	1ET	Nitric oxide synthase, brain	1.14.13.39	0.446