sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 1.000 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.646 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.600 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.574 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.556 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.448 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.445 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3bt9 | DEQ | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.443 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.443 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.441 |