Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4u140HKMuscarinic acetylcholine receptor M3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4u140HKMuscarinic acetylcholine receptor M3/1.000
4u150HKMuscarinic acetylcholine receptor M3/0.589
4u163C0Muscarinic acetylcholine receptor M3/0.550
3uonQNBMuscarinic acetylcholine receptor M2/0.540
4daj0HKMuscarinic acetylcholine receptor M3/0.530
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.477
2xuqTZ4Acetylcholinesterase3.1.1.70.472
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.470
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.464
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.464
2xufTZ4Acetylcholinesterase3.1.1.70.457
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.454
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.450
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.448
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.446
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.446
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
1q83TZ5Acetylcholinesterase3.1.1.70.443
2wzySQXSoluble acetylcholine receptor/0.441