Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4tlbAGSCircadian clock protein kinase KaiC2.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4tlbAGSCircadian clock protein kinase KaiC2.7.11.11.000
4tlcAGSCircadian clock protein kinase KaiC2.7.11.10.629
4tl9AGSCircadian clock protein kinase KaiC2.7.11.10.613
4tl7ATPCircadian clock protein kinase KaiC2.7.11.10.587
3dvlATPCircadian clock protein kinase KaiC2.7.11.10.578
4tl6ANPCircadian clock protein kinase KaiC2.7.11.10.576
3s1aATPCircadian clock protein kinase KaiC2.7.11.10.572
4tldAGSCircadian clock protein kinase KaiC2.7.11.10.565
4tleAGSCircadian clock protein kinase KaiC2.7.11.10.564
3jzmATPCircadian clock protein kinase KaiC2.7.11.10.557
1tf7ATPCircadian clock protein kinase KaiC2.7.11.10.541
1u9iATPCircadian clock protein kinase KaiC2.7.11.10.540
2gblATPCircadian clock protein kinase KaiC2.7.11.10.539
4o0mATPCircadian clock protein kinase KaiC2.7.11.10.535
4tl8AGSCircadian clock protein kinase KaiC2.7.11.10.531
4tlaADPCircadian clock protein kinase KaiC2.7.11.10.511
3k0fATPCircadian clock protein kinase KaiC2.7.11.10.481
2dr3ADPUPF0273 protein PH0284/0.458
3k0aATPCircadian clock protein kinase KaiC2.7.11.10.453