Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ryvZEAProtein LlR18A

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ryvZEAProtein LlR18A/1.000
1kkq471Peroxisome proliferator-activated receptor alpha/0.481
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.477
2pobGW4Peroxisome proliferator-activated receptor gamma/0.471
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.470
3zuyTCHTransporter/0.470
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.468
1zeoC01Peroxisome proliferator-activated receptor gamma/0.466
3vt8YI3Vitamin D3 receptor/0.461
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.460
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1ppjANYCytochrome b/0.458
2po7CHDFerrochelatase, mitochondrial4.99.1.10.456
3zuxTCHTransporter/0.456
4ips1G4Mycocyclosin synthase1.14.21.90.456
3cv9VDXVitamin D3 dihydroxylase/0.455
3a1nNADNDP-sugar epimerase/0.453
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
4h1e10JBeta-secretase 13.4.23.460.453
1rv1IMZE3 ubiquitin-protein ligase Mdm26.3.20.451
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.451
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.450
3drcMTXDihydrofolate reductase1.5.1.30.450
3oqkS52Renin3.4.23.150.450
4ipw1G7Mycocyclosin synthase1.14.21.90.450
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.449
3s7a684Dihydrofolate reductase1.5.1.30.449
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2uxoTACHTH-type transcriptional regulator TtgR/0.448
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4v2gITCTetracycline repressor protein class D/0.448
1uyePU9Heat shock protein HSP 90-alpha/0.447
2uxpCLMHTH-type transcriptional regulator TtgR/0.447
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1k7l544Peroxisome proliferator-activated receptor alpha/0.446
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4uymVOR14-alpha sterol demethylase Cyp51B/0.445
1x8lOXRRetinol dehydratase/0.444
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.444
1jipKTN6-deoxyerythronolide B hydroxylase/0.443
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2znnS44Peroxisome proliferator-activated receptor alpha/0.443
3gobHXXDdmC/0.443
3slkNDPPolyketide synthase extender module 2/0.443
4cd2FOLDihydrofolate reductase1.5.1.30.443
4lxhC1EAlpha/beta hydrolase fold/0.443
5itzLOCTubulin beta-2B chain/0.443
1fm9570Peroxisome proliferator-activated receptor gamma/0.442
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
3l0lHC3Nuclear receptor ROR-gamma/0.442
3v76FDAUncharacterized protein/0.442
3vt9YI4Vitamin D3 receptor/0.442
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.441
1jioDEB6-deoxyerythronolide B hydroxylase/0.441
1nzdUPGDNA beta-glucosyltransferase/0.441
2vn0TDZCytochrome P450 2C8/0.441
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.441
4o701QKBromodomain-containing protein 4/0.441
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1k6tXN1Gag-Pol polyprotein3.4.23.160.440
1xddAAYIntegrin alpha-L/0.440
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.440
4dfrMTXDihydrofolate reductase1.5.1.30.440