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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4rtmSAMDNA adenine methylase2.1.1.72

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4rtmSAMDNA adenine methylase2.1.1.721.000
4rtkSAHDNA adenine methylase2.1.1.720.667
4rtjSFGDNA adenine methylase2.1.1.720.660
4gbeSAHDNA adenine methylase2.1.1.720.606
4rtsSAMDNA adenine methylase2.1.1.720.599
2g1pSAHDNA adenine methylase2.1.1.720.577
4rtrSAMDNA adenine methylase2.1.1.720.576
4golSA8DNA adenine methylase2.1.1.720.571
4rtpSAMDNA adenine methylase2.1.1.720.561
4rtlSFGDNA adenine methylase2.1.1.720.533
2oreSAHDNA adenine methylase2.1.1.720.530
2dpmSAMModification methylase DpnIIA2.1.1.720.520
4rtoSFGDNA adenine methylase2.1.1.720.507
4rtnSAHDNA adenine methylase2.1.1.720.503
4rtqSAHDNA adenine methylase2.1.1.720.466