sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4rrz | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4rrw | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 1.000 | |
| 4rrz | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 1.000 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.665 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.662 | |
| 4oty | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.659 | |
| 3ln1 | CEL | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.610 | |
| 5ikq | JMS | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.610 | |
| 6cox | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.608 | |
| 3rr3 | FLR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.607 | |
| 4cox | IMN | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.597 | |
| 5ikr | ID8 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.590 | |
| 4fm5 | DF0 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.585 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.580 | |
| 2oyu | IMS | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.562 | |
| 1q4g | BFL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.560 | |
| 3n8x | NIM | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.558 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.554 | |
| 1eqh | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.553 | |
| 1cx2 | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.547 | |
| 3n8w | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.547 | |
| 4ph9 | IBP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.535 | |
| 1ht5 | FL2 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.532 | |
| 1eqg | IBP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.528 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.528 | |
| 1ht8 | 34C | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.524 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.523 | |
| 3kk6 | CEL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.517 | |
| 2ayl | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.514 | |
| 3n8y | DIF | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.509 | |
| 3n8z | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.503 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.501 | |
| 5ikt | TLF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.501 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.489 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.486 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.484 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.483 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.481 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.481 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.479 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.477 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.477 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.476 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.472 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.472 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.470 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.470 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.469 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.468 | |
| 4iae | 1DX | Alr2278 protein | / | 0.468 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.467 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.466 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.465 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.464 | |
| 1eio | GCH | Gastrotropin | / | 0.464 | |
| 1fml | RTL | Retinol dehydratase | / | 0.464 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.464 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.463 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.462 | |
| 3r0t | FU9 | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.462 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.462 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 3lit | E15 | Protease | / | 0.461 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.460 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.460 | |
| 5fbh | TCR | Extracellular calcium-sensing receptor | / | 0.460 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.459 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 3b9l | AZZ | Serum albumin | / | 0.459 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.459 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.458 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.458 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.458 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.457 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.457 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 2xvw | 9NR | Serum albumin | / | 0.456 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.456 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.456 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.455 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.455 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.455 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.455 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.454 | |
| 1kqg | HQO | Formate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit | / | 0.454 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.454 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.454 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.454 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.453 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.453 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.452 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.452 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.452 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.452 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.451 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.451 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.451 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.451 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.451 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.451 | |
| 4iah | 1DX | Alr2278 protein | / | 0.451 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.451 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.451 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.450 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.450 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.450 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1jr8 | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.449 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.449 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.449 | |
| 1hk3 | T44 | Serum albumin | / | 0.448 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.448 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.448 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.448 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.448 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1g28 | FMN | PHY3 | / | 0.447 | |
| 1hk1 | T44 | Serum albumin | / | 0.447 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.447 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.447 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.447 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.447 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.447 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.447 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.447 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.446 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1z1f | STL | Resveratrol synthase | / | 0.446 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2bxm | IMN | Serum albumin | / | 0.446 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.446 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.446 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.445 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.445 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4a2z | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.445 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.444 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2oxt | SAM | Genome polyprotein | / | 0.444 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.444 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.444 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.444 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.444 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1uom | PTI | Estrogen receptor | / | 0.443 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.443 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 2imf | TOM | 2-hydroxychromene-2-carboxylate isomerase | 5.99.1.4 | 0.443 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.443 | |
| 2xvu | 9DN | Serum albumin | / | 0.443 | |
| 2xvv | 9DN | Serum albumin | / | 0.443 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.443 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.443 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.443 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 4h6p | FMN | Chromate reductase | / | 0.443 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.443 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.443 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.443 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.442 | |
| 2wes | FAD | Tryptophan 5-halogenase | / | 0.442 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.442 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.442 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.442 | |
| 4a32 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.442 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.442 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.441 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.441 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.441 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.441 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3liv | E16 | Protease | / | 0.441 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.441 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.441 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.441 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.441 | |
| 4kfo | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 4l9k | EHF | Serum albumin | / | 0.441 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.441 | |
| 5a27 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 5dp2 | NAP | CurF | / | 0.441 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.441 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1h5t | TYD | Glucose-1-phosphate thymidylyltransferase 1 | / | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.440 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.440 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.440 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2yem | WSH | Bromodomain-containing protein 4 | / | 0.440 | |
| 2yiw | YIW | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3aba | FLI | Cytochrome P450 | / | 0.440 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.440 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.440 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.440 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.440 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.440 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.440 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.440 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.440 |