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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4rrmA3TProbable threonine--tRNA ligase 26.1.1.3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4rrmA3TProbable threonine--tRNA ligase 26.1.1.31.000
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.755
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.708
4rrbA3TProbable threonine--tRNA ligase 26.1.1.30.699
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.692
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.653
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.635
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.627
4rr9A3SProbable threonine--tRNA ligase 26.1.1.30.623
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.622
2hl0A3SThreonine--tRNA ligase6.1.1.30.618
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.615
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.612
4rrjA3SProbable threonine--tRNA ligase 26.1.1.30.593
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.592
3pd2A3SThreonine--tRNA ligase6.1.1.30.587
2hl1A3SThreonine--tRNA ligase6.1.1.30.586
4rrgA3TThreonine--tRNA ligase6.1.1.30.585
4rrrA3TThreonine--tRNA ligase6.1.1.30.579
3pd3A3TThreonine--tRNA ligase6.1.1.30.568
3pd4A3GThreonine--tRNA ligase6.1.1.30.565
2hl2SSAThreonine--tRNA ligase6.1.1.30.558
4rrqA3SThreonine--tRNA ligase6.1.1.30.555
4rrfA3SThreonine--tRNA ligase6.1.1.30.519
3h3r14HCollagen type IV alpha-3-binding protein/0.513
1n3rGTPGTP cyclohydrolase 13.5.4.160.498
3pd5TSBThreonine--tRNA ligase6.1.1.30.496
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.495
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.493
2po7CHDFerrochelatase, mitochondrial4.99.1.10.491
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.491
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
2uxoTACHTH-type transcriptional regulator TtgR/0.488
3junAKDPhenazine biosynthesis protein A/B/0.488
3tk3CPZCytochrome P450 2B41.14.14.10.488
4tmcFMNOld yellow enzyme/0.488
4oztP1AEcdysone receptor, putative/0.487
4r81FMNPredicted NADH dehydrogenase/0.487
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.486
3h3t16HCollagen type IV alpha-3-binding protein/0.486
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.486
4dc0NDPPutative ketoacyl reductase1.3.10.486
4ead0NPThymidine phosphorylase2.4.2.40.486
1bwsNDPGDP-L-fucose synthase/0.484
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.484
3pwhZMAAdenosine receptor A2a/0.484
3a783EVVitamin D3 receptor/0.482
3jpuTY4Transcriptional activator protein LasR/0.482
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
4qzuRTLRetinol-binding protein 2/0.482
3f1kNAPUncharacterized oxidoreductase YciK10.481
3h3sH15Collagen type IV alpha-3-binding protein/0.481
5kghACOPredicted acetyltransferase/0.480
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.479
4b8zNAPGDP-L-fucose synthase1.1.1.2710.479
3gwfFADCyclohexanone monooxygenase/0.478
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
2lbaCHOFatty acid binding protein 6/0.477
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
4cdmFO1Deoxyribodipyrimidine photolyase/0.477
3sn6P0GBeta-2 adrenergic receptor/0.477
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.476
3pqbVGPPutative oxidoreductase/0.476
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.476
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
2pvkP45Casein kinase II subunit alpha2.7.11.10.474
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
4in44IDKelch-like ECH-associated protein 1/0.474
4xymCOAAcyl-CoA synthetase (NDP forming)/0.474
4itfTFYVitamin D3 receptor/0.473
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.472
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.472
4enhFVXCholesterol 24-hydroxylase/0.472
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.471
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.471
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.471
1kqwRTLCellular retinol-binding protein type II/0.470
1zdwFLVPrenyltransferase/0.470
3inrGDUUDP-galactopyranose mutase5.4.99.90.470
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.470
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3bqdDAYGlucocorticoid receptor/0.469
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3jynNDPQuinone oxidoreductase/0.469
4cfaWOPIntegrase/0.469
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.468
1r2jFADFkbI/0.468
2fhnBNIAvidin-related protein 4/5/0.468
3vf60H6Glucokinase2.7.1.20.468
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
1qorNDPQuinone oxidoreductase 1/0.467
2ea4F79Methionine aminopeptidase 2/0.467
3q44D50M1 family aminopeptidase3.4.110.467
3v49PK0Androgen receptor/0.467
4yaw2AMNADPH--cytochrome P450 reductase/0.467
2qimZEAClass 10 plant pathogenesis-related protein/0.466
2xviFADPutative flavin-containing monooxygenase/0.466
3d8vUD1Bifunctional protein GlmU/0.466
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3n0bFADFlavin-dependent thymidylate synthase2.1.1.1480.466
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
2gv8NDPThiol-specific monooxygenase1.14.130.465
3ha5SFGHydroxymycolate synthase MmaA42.1.10.465
3hazFADBifunctional protein PutA/0.465
3lqfNADGalactitol dehydrogenase/0.465
4bfzZVZPantothenate kinase2.7.1.330.465
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.465
4lsjLSJGlucocorticoid receptor/0.465
1bwlFMNNADPH dehydrogenase 11.6.99.10.464
1vbiNADMalate/L-lactate dehydrogenase family protein/0.464
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.464
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.464
4l0qNADAlcohol dehydrogenase class-3/0.464
4ma628EAra h 8 allergen/0.464
4nieNBHNuclear receptor ROR-gamma/0.464
5kf1ACOPredicted acetyltransferase/0.464
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.463
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.463
2watCOAFatty acid synthase subunit alpha2.3.1.860.463
3c3xNAPEugenol synthase 11.1.1.3180.463
4a6rTA8Probable aminotransferase/0.463
4dijBLFE3 ubiquitin-protein ligase Mdm26.3.20.463
1aj8COACitrate synthase/0.462
1dtpAPUDiphtheria toxin/0.462
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.462
1obnASVIsopenicillin N synthase1.21.3.10.462
2ikuLIYRenin3.4.23.150.462
2xlsFADPutative flavin-containing monooxygenase/0.462
3pe2E1BCasein kinase II subunit alpha2.7.11.10.462
4l8u9AZSerum albumin/0.462
1fmjRTLRetinol dehydratase/0.461
2c29NAPDihydroflavonol 4-reductase/0.461
2fk8SAMHydroxymycolate synthase MmaA42.1.10.461
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.461
2p33J07Mitogen-activated protein kinase 102.7.11.240.461
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.461
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.461
4psbGA3Cytokinin-specific binding protein/0.461
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.460
1xddAAYIntegrin alpha-L/0.460
2bu9HFVIsopenicillin N synthase1.21.3.10.460
2g8yNADHydroxycarboxylate dehydrogenase B/0.460
2ovhAS0Progesterone receptor/0.460
2vnkFADNADPH:ferredoxin reductase/0.460
2xlrFADPutative flavin-containing monooxygenase/0.460
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
4g2i0VQVitamin D3 receptor/0.460
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.460
1j9zFADNADPH--cytochrome P450 reductase/0.459
2abi1CAMineralocorticoid receptor/0.459
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.459
2om9AJAPeroxisome proliferator-activated receptor gamma/0.459
3gncQQQGlutaryl-CoA dehydrogenase/0.459
3h3qH13Collagen type IV alpha-3-binding protein/0.459
4b1fKRHGlutamate racemase/0.459
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
1ddtAPUDiphtheria toxin/0.458
1g6kNADGlucose 1-dehydrogenase1.1.1.470.458
2flhZEACytokinin-specific binding protein/0.458
2pklDHTAndrogen receptor/0.458
2pncCLUPrimary amine oxidase, liver isozyme/0.458
3mdmFJZCholesterol 24-hydroxylase/0.458
3r5zF42Uncharacterized protein/0.458
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.458
4yaoFMNNADPH--cytochrome P450 reductase/0.458
5cvhADPCasein kinase II subunit alpha2.7.11.10.458
5kf1COAPredicted acetyltransferase/0.458
1bwkFMNNADPH dehydrogenase 11.6.99.10.457
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.457
1jg0DDTThymidylate synthase/0.457
1ya3STRMineralocorticoid receptor/0.457
2jfz003Glutamate racemase/0.457
2vqqTFGHistone deacetylase 43.5.1.980.457
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.457
3oqkS52Renin3.4.23.150.457
4g1z0VPVitamin D3 receptor A/0.457
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.457
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1rfuADPPyridoxal kinase2.7.1.350.456
1zeoC01Peroxisome proliferator-activated receptor gamma/0.456
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.456
2tpsTPSThiamine-phosphate synthase/0.456
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.456
3a20FMNFMN-binding protein/0.456
3akn11DFatty acid-binding protein, intestinal/0.456
3ew2BTNHypothetical conserved protein/0.456
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4b8wNAPGDP-L-fucose synthase1.1.1.2710.456
4h9tHL4Phosphotriesterase/0.456
4j7xSASSepiapterin reductase1.1.1.1530.456
4lfiGNPCasein kinase II subunit alpha2.7.11.10.456
4pkwGM6Lethal factor3.4.24.830.456
4y8wSTRSteroid 21-hydroxylase/0.456
5g53NECAdenosine receptor A2a/0.456
1dv2ATPBiotin carboxylase6.3.4.140.455
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1mp0NADAlcohol dehydrogenase class-31.1.1.10.455
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.455
1osvCHCBile acid receptor/0.455
1phhFADp-hydroxybenzoate hydroxylase/0.455
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.455
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
3ekuCY9Actin-5C/0.455
3mtfA3FActivin receptor type-12.7.11.300.455
3p74FMNPentaerythritol tetranitrate reductase/0.455
3pxyJWSCyclin-dependent kinase 22.7.11.220.455
4g67SAHUncharacterized ACR, COG1565 superfamily/0.455
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.455
4n4v2GYTankyrase-12.4.2.300.455
4zm6ACON-acetyl-beta-D glucosaminidase/0.455
1e7qNAPGDP-L-fucose synthase/0.454
1kquBR4Phospholipase A2, membrane associated/0.454
1stpBTNStreptavidin/0.454
1x8lOXRRetinol dehydratase/0.454
1xp8AGSProtein RecA/0.454
1ygkRRCPyridoxal kinase2.7.1.350.454
2e0nSAHPrecorrin-2 C20-methyltransferase/0.454
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.454
2pcgSAHDiphthine synthase/0.454
3akm11DFatty acid-binding protein, intestinal/0.454
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3ixp834Ecdysone receptor/0.454
3kpzZNEVitamin D3 receptor/0.454
3zt2ZT2Integrase/0.454
4i6gFADCryptochrome-2/0.454
4la7A1OAbscisic acid receptor PYL2/0.454
4tkg09LTankyrase-22.4.2.300.454
5a3cNADSIR2 family protein/0.454
5irnADPNucleotide binding oligomerization domain containing 2/0.454
1amoFADNADPH--cytochrome P450 reductase/0.453
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1n83CLRNuclear receptor ROR-alpha/0.453
1nhz486Glucocorticoid receptor/0.453
2cnsACORibosomal-protein-alanine acetyltransferase/0.453
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3gwfNAPCyclohexanone monooxygenase/0.453
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
3p8iFMNPentaerythritol tetranitrate reductase/0.453
4b68NAPL-ornithine N(5)-monooxygenase/0.453
4g090VDHistidinol dehydrogenase/0.453
4xwtU5PRibonuclease J/0.453
3emlZMAAdenosine receptor A2a/0.453
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1jolFFODihydrofolate reductase1.5.1.30.452
1r58AO5Methionine aminopeptidase 2/0.452
2aa6STRMineralocorticoid receptor/0.452
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.452
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.452
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3owaFADAcyl-CoA dehydrogenase/0.452
3vrvYSDVitamin D3 receptor/0.452
4k6fNAPPutative Acetoacetyl-CoA reductase/0.452
4lt63ATPoly(A) polymerase gamma2.7.7.190.452
5a0112VO-glycosyltransferase/0.452
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.452
5kf9ACOPredicted acetyltransferase/0.452
1f5fDHTSex hormone-binding globulin/0.451
1qiqACCIsopenicillin N synthase1.21.3.10.451
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.451
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.451
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.451
2xvq9DSSerum albumin/0.451
3jv7NADSecondary alcohol dehydrogenase/0.451
4dbzNDPPutative ketoacyl reductase1.3.10.451
4eqrCOACoenzyme A disulfide reductase/0.451
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.451
5k2dZMAAdenosine receptor A2a/0.451
1fbyREARetinoic acid receptor RXR-alpha/0.450
1j49NADD-lactate dehydrogenase1.1.1.280.450
1kkq471Peroxisome proliferator-activated receptor alpha/0.450
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.450
2ea2F77Methionine aminopeptidase 2/0.450
2fpcSCGStrictosidine synthase4.3.3.20.450
2jfaRALEstrogen receptor/0.450
2x06NADL-sulfolactate dehydrogenase/0.450
2x9dITCTetracycline repressor protein class D/0.450
2y60M8FIsopenicillin N synthase1.21.3.10.450
2zbaZBATrichothecene 3-O-acetyltransferase/0.450
3i2834NBifunctional epoxide hydrolase 23.3.2.100.450
3nx4NAPPutative oxidoreductase/0.450
3orfNADDihydropteridine reductase1.5.1.340.450
3qgf46FGenome polyprotein2.7.7.480.450
3sh25DRDihydrofolate reductase1.5.1.30.450
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
3vt9YI4Vitamin D3 receptor/0.450
3w0yDS4Vitamin D3 receptor/0.450
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.450
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.450
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.450
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.450
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1m13HYFNuclear receptor subfamily 1 group I member 2/0.449
2rqfJH3Hemolymph juvenile hormone binding protein/0.449
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.449
3fhxPXLPyridoxal kinase2.7.1.350.449
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
3k4nFADPyranose 2-oxidase/0.449
3r7eX88Cyclin-dependent kinase 22.7.11.220.449
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.449
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.449
4a8v2ANMajor pollen allergen Bet v 1-J/0.449
4bb3KKAIsopenicillin N synthase1.21.3.10.449
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4k6i9RARetinoic acid receptor RXR-alpha/0.449
5eccNAPDehydrofolate reductase type I/0.449
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.449
5k2bZMAAdenosine receptor A2a/0.449
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.448
1gpeFADGlucose oxidase1.1.3.40.448
1kvoOAPPhospholipase A2, membrane associated/0.448
1oycFMNNADPH dehydrogenase 11.6.99.10.448
1pw1HELD-alanyl-D-alanine carboxypeptidase3.4.16.40.448
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.448
1q23FUAChloramphenicol acetyltransferase2.3.1.280.448
1rfvADPPyridoxal kinase2.7.1.350.448
1s9qOHTEstrogen-related receptor gamma/0.448
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.448
2p7zOHTEstrogen-related receptor gamma/0.448
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3da24MDCarbonic anhydrase 134.2.1.10.448
3fsjD7KBenzoylformate decarboxylase4.1.1.70.448
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3p3zP3ZPutative cytochrome P450/0.448
3zrbORCProgesterone receptor/0.448
4b65FADL-ornithine N(5)-monooxygenase/0.448
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.448
4e2dFMNDehydrogenase/0.448
4i8vBHFCytochrome P450 1A11.14.14.10.448
4iae1DXAlr2278 protein/0.448
4ipw1G7Mycocyclosin synthase1.14.21.90.448
4ruoBIVVitamin D3 receptor A/0.448
4xz3COAAcyl-CoA synthetase (NDP forming)/0.448
1eioGCHGastrotropin/0.447
1fm4DXCMajor pollen allergen Bet v 1-L/0.447
1rk3VDXVitamin D3 receptor/0.447
2aaxPDNMineralocorticoid receptor/0.447
2gjlFMNNitronate monooxygenase1.13.12.160.447
2iviACWIsopenicillin N synthase1.21.3.10.447
2jb4A14Isopenicillin N synthase1.21.3.10.447
2xvfFADPutative flavin-containing monooxygenase/0.447
3f03FMNPentaerythritol tetranitrate reductase/0.447
3frkTQPQdtB/0.447
3ibdCPZCytochrome P450 2B61.14.130.447
3mj4URMUDP-galactopyranose mutase/0.447
3pgpACOUncharacterized protein/0.447
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.447
3vt7VDXVitamin D3 receptor/0.447
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.447
4ejvLCLTranscriptional regulator TcaR/0.447
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.447
4iteTEYVitamin D3 receptor/0.447
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
1crbRTLRetinol-binding protein 1/0.446
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.446
2fnaADPUncharacterized protein/0.446
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.446
2g1n1IGRenin3.4.23.150.446
2hasC3OVitamin D3 receptor/0.446
2jfhLK1UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
2nmtNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.446
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.446
2xs0ANPMitogen-activated protein kinase 82.7.11.240.446
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.446
3d84NDPDihydrofolate reductase1.5.1.30.446
3fznD7KBenzoylformate decarboxylase4.1.1.70.446
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3vt5YI2Vitamin D3 receptor/0.446
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.446
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.446
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
5a9sNAPPutative dehydrogenase/0.446
4z9g1Q5Corticotropin-releasing factor receptor 1/0.446
3p0gP0GBeta-2 adrenergic receptor/0.446
1fmlRTLRetinol dehydratase/0.445
1mczRMNBenzoylformate decarboxylase4.1.1.70.445
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1sm9NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.445
1xe65FPPlasmepsin-23.4.23.390.445
2dvlFADAcyl-CoA dehydrogenase/0.445
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2g247IGRenin3.4.23.150.445
2pnuENMAndrogen receptor/0.445
2rtoIMIStreptavidin/0.445
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.445
3atzFMNProstaglandin F2a synthase/0.445
3gb4D3MDdmC/0.445
3n0cFADFlavin-dependent thymidylate synthase2.1.1.1480.445
3u8hBHPPhospholipase A2, membrane associated/0.445
3zkyWT4Isopenicillin N synthase1.21.3.10.445
3zraORBProgesterone receptor/0.445
4a83DXCMajor pollen allergen Bet v 1-A/0.445
4dptAGSMevalonate diphosphate decarboxylase/0.445
4ele31IDihydrofolate reductase/0.445
4fvz4KJNitric oxide synthase, brain1.14.13.390.445
4hy6FJ1Heat shock protein HSP 90-alpha/0.445
4j7uYTZSepiapterin reductase1.1.1.1530.445
4jxrACOAcetyltransferase/0.445
4q0kGA3Phytohormone-binding protein/0.445
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1m9k7NINitric oxide synthase, endothelial1.14.13.390.444
1s19MC9Vitamin D3 receptor/0.444
1wsvTHHAminomethyltransferase, mitochondrial/0.444
1yhjR6CPyridoxal kinase2.7.1.350.444
1ykdCMPAdenylate cyclase/0.444
1zgaHMKIsoflavone 4'-O-methyltransferase/0.444
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.444
2b55D31Cyclin-dependent kinase 22.7.11.220.444
2bgjFADNADPH:ferredoxin reductase/0.444
2gtk208Peroxisome proliferator-activated receptor gamma/0.444
2j9gANPBiotin carboxylase6.3.4.140.444
2oazI96Methionine aminopeptidase 2/0.444
2oyuIMSProstaglandin G/H synthase 11.14.99.10.444
3eljGS7Mitogen-activated protein kinase 82.7.11.240.444
3gw9VNILanosterol 14-alpha-demethylase/0.444
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.444
3nxxNDPDihydrofolate reductase1.5.1.30.444
3vrtYS2Vitamin D3 receptor/0.444
3wv9FEGHmd co-occurring protein HcgE/0.444
4b4vL34Bifunctional protein FolD/0.444
4bfvZVVPantothenate kinase2.7.1.330.444
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.444
4e5yNDPGDP-L-fucose synthase1.1.1.2710.444
4k4eK4ETankyrase-12.4.2.300.444
4mv4ACPBiotin carboxylase6.3.4.140.444
4xldBRLPeroxisome proliferator-activated receptor gamma/0.444
5jscFADPutative acyl-CoA dehydrogenase/0.444
4s0vSUVOrexin receptor type 2/0.444
1bnnAL1Carbonic anhydrase 24.2.1.10.443
1dkfBMSRetinoic acid receptor alpha/0.443
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1fm69CRRetinoic acid receptor RXR-alpha/0.443
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.443
1nooCAHCamphor 5-monooxygenase1.14.15.10.443
1synF89Thymidylate synthase/0.443
1tl7FOKAdenylate cyclase type 2/0.443
1tl7FOKAdenylate cyclase type 5/0.443
1uyuCAMCamphor 5-monooxygenase1.14.15.10.443
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.443
2abbFMNPentaerythritol tetranitrate reductase/0.443
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.443
2c12FADNitroalkane oxidase1.7.3.10.443
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.443
2e20B4PPropionate kinase/0.443
2i4qUA4Renin3.4.23.150.443
2pixDHTAndrogen receptor/0.443
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.443
3btjDEQHTH-type transcriptional regulator QacR/0.443
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3eksCY9Actin-5C/0.443
3gy9COAGCN5-related N-acetyltransferase/0.443
3o6o94MHeat shock protein 83/0.443
3rdqDTBStreptavidin/0.443
3s1dZIRCytokinin dehydrogenase 11.5.99.120.443
3tneRITCandidapepsin-13.4.23.240.443
3vtdTKDVitamin D3 receptor/0.443
3w0gW07Vitamin D3 receptor/0.443
3w5p4OAVitamin D3 receptor/0.443
3zsqO4NIntegrase/0.443
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.443
4g1y0VOVitamin D3 receptor A/0.443
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4rupH97Vitamin D3 receptor A/0.443
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.443
5hsaFASAlcohol oxidase 11.1.3.130.443
5jtbZMAAdenosine receptor A2a/0.443
1fxsNAPGDP-L-fucose synthase/0.442
1jt6DEQHTH-type transcriptional regulator QacR/0.442
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.442
1p31EPUUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.442
1tehNADAlcohol dehydrogenase class-31.1.1.10.442
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.442
1v1k3FPCyclin-dependent kinase 22.7.11.220.442
1xq3R18Androgen receptor/0.442
2a4nCOAAac(6')-Ii protein/0.442
2eleSAHDiphthine synthase/0.442
2hcdBIVVitamin D3 receptor A/0.442
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.442
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.442
3arvSAUChitinase A/0.442
3br3ETHTH-type transcriptional regulator QacR/0.442
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.442
3iocA5DPantothenate synthetase6.3.2.10.442
3mnoDEXGlucocorticoid receptor/0.442
3nj0PYVAbscisic acid receptor PYL2/0.442
3ojiPYVAbscisic acid receptor PYL3/0.442
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.442
3sp9IL2Peroxisome proliferator-activated receptor delta/0.442
3t3q9PLCytochrome P450 2A61.14.130.442
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3vspEK8Peroxisome proliferator-activated receptor gamma/0.442
4dpuAGSMevalonate diphosphate decarboxylase/0.442
4e0u0MVCyclic dipeptide N-prenyltransferase/0.442
4egbNADdTDP-glucose 4,6-dehydratase/0.442
4fxy0W2Neurolysin, mitochondrial3.4.24.160.442
4iah1DXAlr2278 protein/0.442
4jseQJ2Nitric oxide synthase, brain1.14.13.390.442
4k7yFMNNADPH dehydrogenase 11.6.99.10.442
4m8hR4MRetinoic acid receptor RXR-alpha/0.442
4ys0ADPProtein translocase subunit SecA/0.442
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
1bsvNDPGDP-L-fucose synthase/0.441
1eyyNAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.441
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.441
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.441
1rkhVD2Vitamin D3 receptor/0.441
1s60COAAminoglycoside N(6')-acetyltransferase type 1/0.441
1stdBFSScytalone dehydratase4.2.1.940.441
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.441
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.441
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.441
2clfF6FTryptophan synthase alpha chain/0.441
2mm3CHOGastrotropin/0.441
2nr4FMNConserved protein/0.441
2oaxSNLMineralocorticoid receptor/0.441
2pvjP44Casein kinase II subunit alpha2.7.11.10.441
2x7gPVBSRSF protein kinase 22.7.11.10.441
2znq401Peroxisome proliferator-activated receptor delta/0.441
3cnjFADCholesterol oxidase1.1.3.60.441
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.441
3k9uACOSpermidine N(1)-acetyltransferase/0.441
3m7rVDXVitamin D3 receptor/0.441
3mqe416Prostaglandin G/H synthase 21.14.99.10.441
3q43D66M1 family aminopeptidase3.4.110.441
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.441
3v0p4GWHisto-blood group ABO system transferase/0.441
4a2aATPCell division protein FtsA/0.441
4a862ANMajor pollen allergen Bet v 1-A/0.441
4cigX0PIntegrase/0.441
4e470N6Histone-lysine N-methyltransferase SETD72.1.1.430.441
4ewhT77Activated CDC42 kinase 1/0.441
4gxs0YSGlutamate receptor 2/0.441
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.441
4uymVOR14-alpha sterol demethylase Cyp51B/0.441
4zu44TGWxcM-like protein/0.441
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.440
1d2sDHTSex hormone-binding globulin/0.440
1db48INPhospholipase A2, membrane associated/0.440
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1o6qR17Squalene--hopene cyclase4.2.1.1290.440
1qvuPRLHTH-type transcriptional regulator QacR/0.440
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.440
1t2cNAIL-lactate dehydrogenase1.1.1.270.440
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.440
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.440
2eh5SAHDiphthine synthase/0.440
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.440
2g1s4IGRenin3.4.23.150.440
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.440
2rr1W8RGenome polyprotein/0.440
2vbdV10Isopenicillin N synthase1.21.3.10.440
2wo7ASVIsopenicillin N synthase1.21.3.10.440
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
2y6fM9FIsopenicillin N synthase1.21.3.10.440
2z9dFMNFMN-dependent NADH-azoreductase/0.440
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.440
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.440
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.440
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3ibqATPPyridoxal kinase/0.440
3il1B5DGlutamate receptor 2/0.440
3jziJZLBiotin carboxylase6.3.4.140.440
3kb1ADPIron-sulfur cluster carrier protein/0.440
3kpkFADSulfide-quinone reductase/0.440
3oapREARetinoic acid receptor RXR-alpha/0.440
3oetNADErythronate-4-phosphate dehydrogenase/0.440
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.440
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.440
3t3r9PLCytochrome P450 2A61.14.130.440
3toxNAPPutative oxidoreductase/0.440
3vqsJT1Genome polyprotein/0.440
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4g7gVFVLanosterol 14-alpha-demethylase/0.440
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4jlj1NMDeoxycytidine kinase2.7.1.740.440
4l5b1UXDeoxycytidine kinase2.7.1.740.440
4l9kEHFSerum albumin/0.440
4nr42LKCREB-binding protein/0.440
4oadCLMUncharacterized protein/0.440
4udcDEXGlucocorticoid receptor/0.440