sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 1.000 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.720 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.674 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.660 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.649 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.646 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.645 | |
| 4rrj | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.613 | |
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.604 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.590 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.588 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.585 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.576 | |
| 4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.558 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.556 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.555 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.553 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.533 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.527 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.524 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.521 | |
| 1r2j | FAD | FkbI | / | 0.519 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.516 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.512 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.506 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.499 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.496 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.496 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.492 | |
| 3frk | TQP | QdtB | / | 0.490 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.488 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.487 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.486 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.485 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.484 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.484 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.484 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.482 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.481 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.481 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.481 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.480 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.480 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.480 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.480 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.480 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.478 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.477 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.477 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.477 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.476 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.476 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.476 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3lu8 | IQX | Serum albumin | / | 0.475 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.475 | |
| 1ddt | APU | Diphtheria toxin | / | 0.474 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.474 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.474 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.474 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.474 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.473 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.472 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.472 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.472 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.472 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.472 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.472 | |
| 4jse | QJ2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.472 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.472 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 3b9l | AZZ | Serum albumin | / | 0.471 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.470 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.470 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.470 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.470 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.469 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.469 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.469 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.469 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.469 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.469 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.468 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.468 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.468 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.468 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.468 | |
| 1hrv | SDZ | Genome polyprotein | / | 0.467 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.467 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.467 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.467 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.467 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.466 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.466 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.466 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.466 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.465 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.465 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.465 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.465 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.465 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.465 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.465 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.464 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.464 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.464 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.464 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1c7o | PPG | Hemolysin | / | 0.463 | |
| 1eio | GCH | Gastrotropin | / | 0.463 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.463 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.463 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.463 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.463 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.463 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.462 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.462 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.461 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 1xj7 | DHT | Androgen receptor | / | 0.461 | |
| 2amb | 17H | Androgen receptor | / | 0.461 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.461 | |
| 2xvv | 9DN | Serum albumin | / | 0.461 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.461 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.461 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.461 | |
| 3p0g | P0G | Beta-2 adrenergic receptor | / | 0.461 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.460 | |
| 1osv | CHC | Bile acid receptor | / | 0.460 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.460 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 1xow | R18 | Androgen receptor | / | 0.460 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.460 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.460 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.460 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4b1f | KRH | Glutamate racemase | / | 0.460 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.459 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.459 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.459 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.459 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.459 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.459 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.459 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4iae | 1DX | Alr2278 protein | / | 0.459 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.459 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.459 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.459 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.458 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.458 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.458 | |
| 2vfz | UPF | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.458 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.458 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.458 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.458 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.458 | |
| 4o28 | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.458 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.458 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.458 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.458 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.457 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.457 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.457 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3m31 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.457 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.457 | |
| 3qs8 | 17D | Anthranilate phosphoribosyltransferase | / | 0.457 | |
| 3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.457 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.457 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.456 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.456 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.456 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.456 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.456 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.456 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.456 | |
| 3up3 | XCA | aceDAF-12 | / | 0.456 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.456 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.456 | |
| 4fw0 | 5KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.456 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.456 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.456 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.455 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.455 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.455 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.455 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.455 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.455 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.455 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.455 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.455 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4b8z | GDP | GDP-L-fucose synthase | 1.1.1.271 | 0.455 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.455 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.455 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.455 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.454 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.454 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.454 | |
| 3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.454 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.454 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.454 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.454 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.454 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.454 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.454 | |
| 4jic | FMN | GTN Reductase | / | 0.454 | |
| 4phl | PIL | Phosphodiesterase | / | 0.454 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.453 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.453 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.453 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.453 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.453 | |
| 2nr4 | FMN | Conserved protein | / | 0.453 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.453 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.453 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.453 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.453 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.453 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.453 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.453 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.453 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.453 | |
| 1ppj | ANY | Cytochrome b | / | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.452 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.452 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.452 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.452 | |
| 3arv | SAU | Chitinase A | / | 0.452 | |
| 3br2 | DEQ | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 3gb4 | D3M | DdmC | / | 0.452 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.452 | |
| 4n1g | CEI | Obelin | / | 0.452 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.452 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.451 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.451 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.451 | |
| 1tys | DHF | Thymidylate synthase | / | 0.451 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.451 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.451 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2e20 | B4P | Propionate kinase | / | 0.451 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.451 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.451 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.451 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.451 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.451 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.451 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.451 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.450 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.450 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.450 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.450 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.450 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.450 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.450 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.450 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.450 | |
| 4kot | CE3 | Uncharacterized protein | / | 0.450 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.450 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.450 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.449 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.449 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.449 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.449 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.449 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.449 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.449 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3eks | CY9 | Actin-5C | / | 0.449 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3oxf | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.449 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.449 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.449 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 4oha | HFT | Androgen receptor | / | 0.449 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.448 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.448 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.448 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.448 | |
| 1pgt | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.448 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.448 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.448 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.448 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.448 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.448 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.448 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.448 | |
| 3zm6 | 2GN | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.448 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.448 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.448 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.448 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.448 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.448 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.447 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.447 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.447 | |
| 3ehj | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.447 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.447 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.447 | |
| 3v49 | PK0 | Androgen receptor | / | 0.447 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.447 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.447 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.447 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.447 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.446 | |
| 1n06 | ADP | Riboflavin kinase | 2.7.1.26 | 0.446 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.446 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.446 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.446 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.446 | |
| 2i5n | UQ1 | Reaction center protein L chain | / | 0.446 | |
| 2o12 | FMN | Chorismate synthase | / | 0.446 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.446 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.446 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.446 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.446 | |
| 3mne | DEX | Glucocorticoid receptor | / | 0.446 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 4l9q | 9TP | Serum albumin | / | 0.446 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.446 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 4zm3 | PLP | Aminotransferase | / | 0.446 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 1dtp | APU | Diphtheria toxin | / | 0.445 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.445 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.445 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.445 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.445 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.445 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.445 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.445 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.445 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.445 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.445 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.445 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.445 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.445 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.445 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.445 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.445 | |
| 4e2d | FMN | Dehydrogenase | / | 0.445 | |
| 4g0k | 0VS | Glutathionyl-hydroquinone reductase YqjG | 1.8 | 0.445 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.445 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.445 | |
| 4zp0 | DXC | Multidrug transporter MdfA | / | 0.445 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.445 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.445 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.444 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.444 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.444 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.444 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.444 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.444 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.444 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.444 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.444 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.444 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.444 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.444 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.444 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.444 | |
| 4y1b | NAP | AntE | / | 0.444 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 5cms | APR | O-acetyl-ADP-ribose deacetylase | / | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.443 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.443 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1zdw | FLV | Prenyltransferase | / | 0.443 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.443 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.443 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 2rs1 | W84 | Genome polyprotein | / | 0.443 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.443 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.443 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.443 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.443 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.443 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.443 | |
| 4c2p | X8Z | Angiotensin-converting enzyme | 3.2.1 | 0.443 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.443 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 4lb2 | DM5 | Serum albumin | / | 0.443 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.443 | |
| 5i2f | BS5 | Histidine triad nucleotide-binding protein 1 | 3 | 0.443 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1jt6 | DEQ | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.442 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.442 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.442 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.442 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.442 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.442 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.442 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.442 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.442 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.442 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.442 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.442 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.441 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.441 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 1xaj | NAD | 3-dehydroquinate synthase | / | 0.441 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.441 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.441 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.441 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.441 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.441 | |
| 3eku | CY9 | Actin-5C | / | 0.441 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.441 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.441 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.441 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4aut | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4ax8 | ADP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.441 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.441 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.441 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4okx | 198 | Androgen receptor | / | 0.441 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1dv2 | ATP | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1kqg | MGD | Formate dehydrogenase, nitrate-inducible, major subunit | 1.1.5.6 | 0.440 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1s36 | CEI | Obelin | / | 0.440 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.440 | |
| 1ye4 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.440 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.440 | |
| 2piw | DHT | Androgen receptor | / | 0.440 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.440 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.440 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.440 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.440 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.440 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.440 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.440 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.440 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.440 |