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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4rrhA3SProbable threonine--tRNA ligase 26.1.1.3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4rrhA3SProbable threonine--tRNA ligase 26.1.1.31.000
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.791
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.698
4rrbA3TProbable threonine--tRNA ligase 26.1.1.30.690
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.635
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.633
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.633
4rr9A3SProbable threonine--tRNA ligase 26.1.1.30.605
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.600
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.582
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.575
3pd2A3SThreonine--tRNA ligase6.1.1.30.572
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.561
3pd3A3TThreonine--tRNA ligase6.1.1.30.560
2hl0A3SThreonine--tRNA ligase6.1.1.30.548
4rrrA3TThreonine--tRNA ligase6.1.1.30.547
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.546
4rrjA3SProbable threonine--tRNA ligase 26.1.1.30.543
3pd4A3GThreonine--tRNA ligase6.1.1.30.542
2hl2SSAThreonine--tRNA ligase6.1.1.30.541
2hl1A3SThreonine--tRNA ligase6.1.1.30.530
4rrgA3TThreonine--tRNA ligase6.1.1.30.514
4rrqA3SThreonine--tRNA ligase6.1.1.30.514
4s0vSUVOrexin receptor type 2/0.512
3pd5TSBThreonine--tRNA ligase6.1.1.30.510
1xddAAYIntegrin alpha-L/0.502
4rrfA3SThreonine--tRNA ligase6.1.1.30.499
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.497
3junAKDPhenazine biosynthesis protein A/B/0.492
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.490
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.489
1q23FUAChloramphenicol acetyltransferase2.3.1.280.488
1bwsNDPGDP-L-fucose synthase/0.487
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.487
2dvlFADAcyl-CoA dehydrogenase/0.487
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.485
2po7CHDFerrochelatase, mitochondrial4.99.1.10.484
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.484
1h51FMNPentaerythritol tetranitrate reductase/0.483
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3sn6P0GBeta-2 adrenergic receptor/0.483
1fmjRTLRetinol dehydratase/0.480
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.479
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.478
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.477
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.477
3h3t16HCollagen type IV alpha-3-binding protein/0.477
1y0s331Peroxisome proliferator-activated receptor delta/0.476
3s1dZIRCytokinin dehydrogenase 11.5.99.120.476
1p8dCO1Oxysterols receptor LXR-beta/0.475
1vbiNADMalate/L-lactate dehydrogenase family protein/0.475
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
4fw05KJNitric oxide synthase, brain1.14.13.390.475
5k2bZMAAdenosine receptor A2a/0.475
2qimZEAClass 10 plant pathogenesis-related protein/0.474
3b9lAZZSerum albumin/0.474
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.474
4a81DXCMajor pollen allergen Bet v 1-A/0.474
1rneC60Renin3.4.23.150.473
2p5uNADUDP-glucose 4-epimerase/0.472
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.472
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.471
2zbaZBATrichothecene 3-O-acetyltransferase/0.471
3w0yDS4Vitamin D3 receptor/0.471
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.470
3v0p4GWHisto-blood group ABO system transferase/0.470
1obnASVIsopenicillin N synthase1.21.3.10.469
2iviACWIsopenicillin N synthase1.21.3.10.469
3tk3CPZCytochrome P450 2B41.14.14.10.469
3vtbTKAVitamin D3 receptor/0.469
4xba5GPAprataxin-like protein30.469
4zj8SUVOrexin receptor type 1/0.469
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.468
1uzwCDHIsopenicillin N synthase1.21.3.10.468
3frkTQPQdtB/0.468
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3nxxNDPDihydrofolate reductase1.5.1.30.468
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.468
1cqp803Integrin alpha-L/0.467
1xe65FPPlasmepsin-23.4.23.390.467
3gwfFADCyclohexanone monooxygenase/0.467
3zoiM2WIsopenicillin N synthase1.21.3.10.467
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1rq1FADEndoplasmic oxidoreductin-11.8.40.466
3h3r14HCollagen type IV alpha-3-binding protein/0.466
4a8v2ANMajor pollen allergen Bet v 1-J/0.466
4ipw1G7Mycocyclosin synthase1.14.21.90.466
2ikuLIYRenin3.4.23.150.465
3l63CAMCamphor 5-monooxygenase1.14.15.10.465
4bfvZVVPantothenate kinase2.7.1.330.465
4dc0NDPPutative ketoacyl reductase1.3.10.465
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.465
1bygSTUTyrosine-protein kinase CSK/0.464
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.464
3ts1TYATyrosine--tRNA ligase6.1.1.10.464
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.464
4tmcFMNOld yellow enzyme/0.464
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.463
1bk0ACVIsopenicillin N synthase1.21.3.10.463
1fxsNAPGDP-L-fucose synthase/0.463
1h50FMNPentaerythritol tetranitrate reductase/0.463
2xvq9DSSerum albumin/0.463
3atzFMNProstaglandin F2a synthase/0.463
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3hazFADBifunctional protein PutA/0.463
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.463
1hb3SCVIsopenicillin N synthase1.21.3.10.462
1pdhFASp-hydroxybenzoate hydroxylase/0.462
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
3b9oFMNAlkane monoxygenase/0.462
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.462
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
3up3XCAaceDAF-12/0.462
3zeiAWHO-acetylserine sulfhydrylase/0.462
4bfzZVZPantothenate kinase2.7.1.330.462
1kquBR4Phospholipase A2, membrane associated/0.461
2jb4A14Isopenicillin N synthase1.21.3.10.461
2qbmCAMCamphor 5-monooxygenase1.14.15.10.461
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3sdi3SDProteasome subunit beta type-53.4.25.10.461
3sdi3SDProteasome subunit beta type-63.4.25.10.461
1hrvSDZGenome polyprotein/0.460
1m13HYFNuclear receptor subfamily 1 group I member 2/0.460
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.460
2xlrFADPutative flavin-containing monooxygenase/0.460
3w0jT08Vitamin D3 receptor/0.460
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.460
1uyuCAMCamphor 5-monooxygenase1.14.15.10.459
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3o6o94MHeat shock protein 83/0.459
4bb3KKAIsopenicillin N synthase1.21.3.10.459
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4qzuRTLRetinol-binding protein 2/0.459
1hb1OCVIsopenicillin N synthase1.21.3.10.458
2g247IGRenin3.4.23.150.458
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.458
4ead0NPThymidine phosphorylase2.4.2.40.458
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.458
1zg32HIIsoflavone 4'-O-methyltransferase/0.457
3gqvNAPEnoyl reductase LovC10.457
3zkyWT4Isopenicillin N synthase1.21.3.10.457
4gddNAIUDP-galactopyranose mutase/0.457
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.457
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.456
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
2c29NAPDihydroflavonol 4-reductase/0.456
2il2LIXRenin3.4.23.150.456
3t2kFADSulfide-quinone reductase/0.456
3vt9YI4Vitamin D3 receptor/0.456
4a6rTA8Probable aminotransferase/0.456
4o74R78Bromodomain-containing protein 4/0.456
5eccNAPDehydrofolate reductase type I/0.456
1g63FMNEpidermin decarboxylase4.1.10.455
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1mczRMNBenzoylformate decarboxylase4.1.1.70.455
2bu9HFVIsopenicillin N synthase1.21.3.10.455
2v59LZKBiotin carboxylase6.3.4.140.455
2vn0TDZCytochrome P450 2C8/0.455
2xviFADPutative flavin-containing monooxygenase/0.455
3inrGDUUDP-galactopyranose mutase5.4.99.90.455
3p74FMNPentaerythritol tetranitrate reductase/0.455
3pm9FADPutative oxidoreductase/0.455
4cdmFO1Deoxyribodipyrimidine photolyase/0.455
4gdcNDPUDP-galactopyranose mutase/0.455
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.454
1txtCAAHMG-CoA synthase/0.454
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.454
2x7hPFNProstaglandin reductase 310.454
3a783EVVitamin D3 receptor/0.454
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.454
3nr4PYVAbscisic acid receptor PYL2/0.454
3v0m5GWHisto-blood group ABO system transferase/0.454
3w0gW07Vitamin D3 receptor/0.454
4elb34RDihydrofolate reductase/0.454
4itfTFYVitamin D3 receptor/0.454
4jlj1NMDeoxycytidine kinase2.7.1.740.454
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.454
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.453
1nw5SAMModification methylase RsrI2.1.1.720.453
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.453
2feuCAMCamphor 5-monooxygenase1.14.15.10.453
2hc4VDXVitamin D3 receptor A/0.453
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.453
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.453
3b70NAPEnoyl reductase LovC10.453
3pe2E1BCasein kinase II subunit alpha2.7.11.10.453
3qm4PN0Cytochrome P450 2D6/0.453
3v0o4GWHisto-blood group ABO system transferase/0.453
3wrhCAMCamphor 5-monooxygenase1.14.15.10.453
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.453
4oztP1AEcdysone receptor, putative/0.453
4yauFADNADPH--cytochrome P450 reductase/0.453
5bp9SAHPutative methyltransferase protein/0.453
1h63FMNPentaerythritol tetranitrate reductase/0.452
1ia3TQ5Dihydrofolate reductase1.5.1.30.452
1r2jFADFkbI/0.452
1s0zEB1Vitamin D3 receptor/0.452
1vyrFMNPentaerythritol tetranitrate reductase/0.452
1zdwFLVPrenyltransferase/0.452
1zgaHMKIsoflavone 4'-O-methyltransferase/0.452
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.452
2xvv9DNSerum albumin/0.452
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3ebf332Nitric oxide synthase, inducible1.14.13.390.452
3rsv3RSBeta-secretase 13.4.23.460.452
4m4821BSodium-dependent dopamine transporter/0.452
1dr2TAPDihydrofolate reductase1.5.1.30.451
1ia4TQ6Dihydrofolate reductase1.5.1.30.451
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1pw1HELD-alanyl-D-alanine carboxypeptidase3.4.16.40.451
1rd4L08Integrin alpha-L/0.451
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.451
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
2wjoQUDBeta-secretase 13.4.23.460.451
2z9dFMNFMN-dependent NADH-azoreductase/0.451
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
3nga3NGCasein kinase II subunit alpha2.7.11.10.451
3p67FMNPentaerythritol tetranitrate reductase/0.451
3p6mDSOCamphor 5-monooxygenase1.14.15.10.451
3w5rLOAVitamin D3 receptor/0.451
4a802ANMajor pollen allergen Bet v 1-A/0.451
4e2bFMNDehydrogenase/0.451
4fgh0U6Dihydrofolate reductase1.5.1.30.451
4jbtASDCytochrome P450 monooxygenase/0.451
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.451
4qbjNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.451
3pwhZMAAdenosine receptor A2a/0.451
1ie9VDXVitamin D3 receptor/0.450
1nq7ARLNuclear receptor ROR-beta/0.450
1qorNDPQuinone oxidoreductase 1/0.450
2gevCOKPantothenate kinase2.7.1.330.450
2vbpVB1Isopenicillin N synthase1.21.3.10.450
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.450
2zjmF1MBeta-secretase 13.4.23.460.450
3f63GTXGlutathione transferase GST1-4/0.450
3ufl508Beta-secretase 13.4.23.460.450
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.450
4du82P0Mevalonate diphosphate decarboxylase/0.450
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.450
4r1lADPPhenylacetate-coenzyme A ligase/0.450
5k2aZMAAdenosine receptor A2a/0.450
5k2dZMAAdenosine receptor A2a/0.450
1db48INPhospholipase A2, membrane associated/0.449
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1kqwRTLCellular retinol-binding protein type II/0.449
1mrqSTRAldo-keto reductase family 1 member C1/0.449
1psa0ZLPepsin A3.4.23.10.449
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.449
1tehNADAlcohol dehydrogenase class-31.1.1.10.449
2tpsTPSThiamine-phosphate synthase/0.449
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.449
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.449
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3imgBZ2Pantothenate synthetase6.3.2.10.449
3kr5BEYM17 leucyl aminopeptidase/0.449
3lu8IQXSerum albumin/0.449
3p8iFMNPentaerythritol tetranitrate reductase/0.449
3q43D66M1 family aminopeptidase3.4.110.449
3up0D7SaceDAF-12/0.449
3vqsJT1Genome polyprotein/0.449
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.449
4jauADPSensor histidine kinase/0.449
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.449
5k2cZMAAdenosine receptor A2a/0.449
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.448
1x8lOXRRetinol dehydratase/0.448
2i4qUA4Renin3.4.23.150.448
2vfzUPFN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.448
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
2ym2NAPPhenylacetone monooxygenase1.14.13.920.448
3f03FMNPentaerythritol tetranitrate reductase/0.448
3g72A6TRenin3.4.23.150.448
3t88S0N1,4-dihydroxy-2-naphthoyl-CoA synthase/0.448
4b1fKRHGlutamate racemase/0.448
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.448
4o1mNADEnoyl-acyl carrier reductase/0.448
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.448
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.447
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.447
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.447
1rk3VDXVitamin D3 receptor/0.447
2g1s4IGRenin3.4.23.150.447
2hamC33Vitamin D3 receptor/0.447
2rqfJH3Hemolymph juvenile hormone binding protein/0.447
2zlcVDXVitamin D3 receptor/0.447
3fwgCAMCamphor 5-monooxygenase1.14.15.10.447
3hz5Z64Heat shock protein HSP 90-alpha/0.447
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3oafOAGDihydrofolate reductase1.5.1.30.447
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.447
4r81FMNPredicted NADH dehydrogenase/0.447
5cccDDFDihydrofolate reductase1.5.1.30.447
5hs1VORLanosterol 14-alpha demethylase/0.447
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1n83CLRNuclear receptor ROR-alpha/0.446
1ygkRRCPyridoxal kinase2.7.1.350.446
1ykdCMPAdenylate cyclase/0.446
2a1nCAMCamphor 5-monooxygenase1.14.15.10.446
2abbFMNPentaerythritol tetranitrate reductase/0.446
2ejvNADL-threonine 3-dehydrogenase/0.446
2hw2RFPRifampin ADP-ribosyl transferase/0.446
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.446
2o4rVD5Vitamin D3 receptor/0.446
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.446
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.446
2vbdV10Isopenicillin N synthase1.21.3.10.446
2w9hTOPDihydrofolate reductase1.5.1.30.446
2z3uCRRCytochrome P450/0.446
3b6zCO7Enoyl reductase LovC10.446
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.446
3e6oA55Nitric oxide synthase, inducible1.14.13.390.446
3fwiCAMCamphor 5-monooxygenase1.14.15.10.446
3oev3OEProteasome subunit beta type-53.4.25.10.446
3oev3OEProteasome subunit beta type-63.4.25.10.446
3oqfS51Renin3.4.23.150.446
3p62FMNPentaerythritol tetranitrate reductase/0.446
3q44D50M1 family aminopeptidase3.4.110.446
3tjzGNPADP-ribosylation factor 1/0.446
3w0aDS5Vitamin D3 receptor/0.446
4a862ANMajor pollen allergen Bet v 1-A/0.446
4e2dFMNDehydrogenase/0.446
4h9506UDihydrofolate reductase1.5.1.30.446
4jnm1LJNicotinamide phosphoribosyltransferase2.4.2.120.446
4yekTHMThymidine phosphorylase/0.446
1f5fDHTSex hormone-binding globulin/0.445
1oc1ASVIsopenicillin N synthase1.21.3.10.445
1ppjANYCytochrome b/0.445
1w6hTITPlasmepsin-23.4.23.390.445
2c12FADNitroalkane oxidase1.7.3.10.445
2lbaCHOFatty acid binding protein 6/0.445
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.445
2x7gPVBSRSF protein kinase 22.7.11.10.445
3gncQQQGlutaryl-CoA dehydrogenase/0.445
3w78CBDFMN-dependent NADH-azoreductase/0.445
4b65FADL-ornithine N(5)-monooxygenase/0.445
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4iteTEYVitamin D3 receptor/0.445
4itmATPTetraacyldisaccharide 4'-kinase/0.445
4lsjLSJGlucocorticoid receptor/0.445
3emlZMAAdenosine receptor A2a/0.445
1bwkFMNNADPH dehydrogenase 11.6.99.10.444
1d2sDHTSex hormone-binding globulin/0.444
1dz4CAMCamphor 5-monooxygenase1.14.15.10.444
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444
1osvCHCBile acid receptor/0.444
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.444
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.444
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3fc6REARetinoic acid receptor RXR-alpha/0.444
3ha5SFGHydroxymycolate synthase MmaA42.1.10.444
3ibqATPPyridoxal kinase/0.444
3m31FADEndoplasmic oxidoreductin-11.8.40.444
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.444
3svj4LIPeptide deformylase/0.444
3t3r9PLCytochrome P450 2A61.14.130.444
3tqhNDPQuinone oxidoreductase/0.444
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
3vrtYS2Vitamin D3 receptor/0.444
3vrvYSDVitamin D3 receptor/0.444
3w5p4OAVitamin D3 receptor/0.444
4bfuZVUPantothenate kinase2.7.1.330.444
4ejvLCLTranscriptional regulator TcaR/0.444
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.444
4jr51LSNicotinamide phosphoribosyltransferase2.4.2.120.444
4mv8ACPBiotin carboxylase6.3.4.140.444
4o281QSNicotinamide phosphoribosyltransferase2.4.2.120.444
4yntFDAGlucose oxidase, putative/0.444
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.444
1b87ACOAac(6')-Ii protein/0.443
1bnnAL1Carbonic anhydrase 24.2.1.10.443
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.443
1g6oADPCag alpha/0.443
1m78NDPDihydrofolate reductase1.5.1.30.443
1nhkCMPNucleoside diphosphate kinase2.7.4.60.443
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.443
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
1yw8A75Methionine aminopeptidase 2/0.443
2cy0NAPShikimate dehydrogenase (NADP(+))/0.443
2jfaRALEstrogen receptor/0.443
2vcmM11Isopenicillin N synthase1.21.3.10.443
2xytTC9Soluble acetylcholine receptor/0.443
2zb8IMNProstaglandin reductase 21.3.1.480.443
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.443
3ix3OHNTranscriptional activator protein LasR/0.443
3mlaJJZProbable nicotinate-nucleotide adenylyltransferase/0.443
3mnrSD1Heat shock protein HSP 90-alpha/0.443
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3njuANNAcidic phospholipase A2 33.1.1.40.443
3own3OXRenin3.4.23.150.443
3vt3VDXVitamin D3 receptor/0.443
3wrlCAMCamphor 5-monooxygenase1.14.15.10.443
3wrmCAMCamphor 5-monooxygenase1.14.15.10.443
4au7SAHHistone-lysine N-methyltransferase KMT5C2.1.1.430.443
4f650S9Fibroblast growth factor receptor 1/0.443
4i1nFOLDihydrofolate reductase1.5.1.30.443
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.443
4o2bLOCTubulin beta-2B chain/0.443
4q71FADBifunctional protein PutA/0.443
4zm3PLPAminotransferase/0.443
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.442
1ex75GPGuanylate kinase2.7.4.80.442
1if7SBRCarbonic anhydrase 24.2.1.10.442
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1lbcCYZGlutamate receptor 2/0.442
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.442
1qrpHH0Pepsin A-43.4.23.10.442
1rf9DBRCamphor 5-monooxygenase1.14.15.10.442
1rj6AZMCarbonic anhydrase 144.2.1.10.442
1y4sADPChaperone protein HtpG/0.442
2ejzSAHDiphthine synthase/0.442
2g20L1ARenin3.4.23.150.442
2iko7IGRenin3.4.23.150.442
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.442
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2wd8VGFPteridine reductase/0.442
2wo7ASVIsopenicillin N synthase1.21.3.10.442
3gfbNADL-threonine 3-dehydrogenase/0.442
3kpzZNEVitamin D3 receptor/0.442
3n62XFJNitric oxide synthase, brain1.14.13.390.442
3oqkS52Renin3.4.23.150.442
3rtnRTNBeta-secretase 13.4.23.460.442
4b4w9L9Bifunctional protein FolD/0.442
4gk3L87Ephrin type-A receptor 32.7.10.10.442
4n1gCEIObelin/0.442
4o761M3Bromodomain-containing protein 4/0.442
4yaoFMNNADPH--cytochrome P450 reductase/0.442
5kghACOPredicted acetyltransferase/0.442
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.441
1rfuADPPyridoxal kinase2.7.1.350.441
1rszDIHPurine nucleoside phosphorylase2.4.2.10.441
1yrdCAMCamphor 5-monooxygenase1.14.15.10.441
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.441
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.441
2gjlFMNNitronate monooxygenase1.13.12.160.441
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.441
2hcdBIVVitamin D3 receptor A/0.441
2hk9NAPShikimate dehydrogenase (NADP(+))/0.441
2p33J07Mitogen-activated protein kinase 102.7.11.240.441
2ykbYKBHeat shock protein HSP 90-alpha/0.441
3aezGDPPantothenate kinase2.7.1.330.441
3br3ETHTH-type transcriptional regulator QacR/0.441
3c36KAIGlutamate receptor ionotropic, kainate 1/0.441
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.441
3ixp834Ecdysone receptor/0.441
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3sh25DRDihydrofolate reductase1.5.1.30.441
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3vt8YI3Vitamin D3 receptor/0.441
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.441
4fhh0U3Vitamin D3 receptor A/0.441
4g95OAGDihydrofolate reductase1.5.1.30.441
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.441
4ia1BIVVitamin D3 receptor A/0.441
4lch1WNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.441
4r87COASpermidine N(1)-acetyltransferase/0.441
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
1ep4S11Gag-Pol polyprotein2.7.7.490.440
1hfqMOTDihydrofolate reductase1.5.1.30.440
1kzjCB3Thymidylate synthase/0.440
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.440
1qiqACCIsopenicillin N synthase1.21.3.10.440
1s19MC9Vitamin D3 receptor/0.440
1v35NAIEnoyl-ACP reductase/0.440
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.440
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2bjfDXCCholoylglycine hydrolase3.5.1.240.440
2bktRPFRenin3.4.23.150.440
2fk8SAMHydroxymycolate synthase MmaA42.1.10.440
2v58LZJBiotin carboxylase6.3.4.140.440
2wzySQXSoluble acetylcholine receptor/0.440
2y60M8FIsopenicillin N synthase1.21.3.10.440
3h3qH13Collagen type IV alpha-3-binding protein/0.440
3otwCOAPhosphopantetheine adenylyltransferase/0.440
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.440
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.440
3toxNAPPutative oxidoreductase/0.440
3zhvTDWMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.440
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4j6cSTRCytochrome P450 monooxygenase/0.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.440
4nieNBHNuclear receptor ROR-gamma/0.440
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.440
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.440