Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 1.000 | |
4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.791 | |
4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.698 | |
4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.690 | |
4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.635 | |
4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.633 | |
4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.633 | |
4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.605 | |
4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.600 | |
4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.582 | |
4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.575 | |
3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.572 | |
4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.561 | |
3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.560 | |
2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.548 | |
4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.547 | |
4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.546 | |
4rrj | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.543 | |
3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.542 | |
2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.541 | |
2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.530 | |
4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.514 | |
4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.514 | |
4s0v | SUV | Orexin receptor type 2 | / | 0.512 | |
3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.510 | |
1xdd | AAY | Integrin alpha-L | / | 0.502 | |
4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.499 | |
3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.497 | |
3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.492 | |
4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.492 | |
3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.490 | |
1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.489 | |
1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.488 | |
1bws | NDP | GDP-L-fucose synthase | / | 0.487 | |
1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.487 | |
2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.487 | |
3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.484 | |
4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.484 | |
1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.483 | |
3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.483 | |
1fmj | RTL | Retinol dehydratase | / | 0.480 | |
3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.478 | |
3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.477 | |
3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.477 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.477 | |
1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.476 | |
3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.476 | |
1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.475 | |
1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.475 | |
3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
4fw0 | 5KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.475 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.475 | |
2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.474 | |
3b9l | AZZ | Serum albumin | / | 0.474 | |
3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.474 | |
4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.474 | |
1rne | C60 | Renin | 3.4.23.15 | 0.473 | |
2p5u | NAD | UDP-glucose 4-epimerase | / | 0.472 | |
3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.472 | |
1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.471 | |
3w0y | DS4 | Vitamin D3 receptor | / | 0.471 | |
3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.470 | |
3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.470 | |
1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.469 | |
3vtb | TKA | Vitamin D3 receptor | / | 0.469 | |
4xba | 5GP | Aprataxin-like protein | 3 | 0.469 | |
4zj8 | SUV | Orexin receptor type 1 | / | 0.469 | |
1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.468 | |
1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
3frk | TQP | QdtB | / | 0.468 | |
3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.468 | |
1cqp | 803 | Integrin alpha-L | / | 0.467 | |
1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.467 | |
3gwf | FAD | Cyclohexanone monooxygenase | / | 0.467 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.466 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.466 | |
4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.466 | |
4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.466 | |
2iku | LIY | Renin | 3.4.23.15 | 0.465 | |
3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.465 | |
4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
1byg | STU | Tyrosine-protein kinase CSK | / | 0.464 | |
1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.464 | |
3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.464 | |
4tmc | FMN | Old yellow enzyme | / | 0.464 | |
1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.463 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
1fxs | NAP | GDP-L-fucose synthase | / | 0.463 | |
1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
2xvq | 9DS | Serum albumin | / | 0.463 | |
3atz | FMN | Prostaglandin F2a synthase | / | 0.463 | |
3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
3haz | FAD | Bifunctional protein PutA | / | 0.463 | |
4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.463 | |
1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.462 | |
2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
3b9o | FMN | Alkane monoxygenase | / | 0.462 | |
3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.462 | |
3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
3up3 | XCA | aceDAF-12 | / | 0.462 | |
3zei | AWH | O-acetylserine sulfhydrylase | / | 0.462 | |
4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.462 | |
1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.461 | |
2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.461 | |
3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.461 | |
1hrv | SDZ | Genome polyprotein | / | 0.460 | |
1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.460 | |
2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
3w0j | T08 | Vitamin D3 receptor | / | 0.460 | |
4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.460 | |
1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
3o6o | 94M | Heat shock protein 83 | / | 0.459 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
4qzu | RTL | Retinol-binding protein 2 | / | 0.459 | |
1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
2g24 | 7IG | Renin | 3.4.23.15 | 0.458 | |
3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.458 | |
4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.458 | |
4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.458 | |
1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.457 | |
3gqv | NAP | Enoyl reductase LovC | 1 | 0.457 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
4gdd | NAI | UDP-galactopyranose mutase | / | 0.457 | |
5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.457 | |
1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.456 | |
1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.456 | |
2il2 | LIX | Renin | 3.4.23.15 | 0.456 | |
3t2k | FAD | Sulfide-quinone reductase | / | 0.456 | |
3vt9 | YI4 | Vitamin D3 receptor | / | 0.456 | |
4a6r | TA8 | Probable aminotransferase | / | 0.456 | |
4o74 | R78 | Bromodomain-containing protein 4 | / | 0.456 | |
5ecc | NAP | Dehydrofolate reductase type I | / | 0.456 | |
1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.455 | |
1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.455 | |
2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.455 | |
2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.455 | |
2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.455 | |
3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
3pm9 | FAD | Putative oxidoreductase | / | 0.455 | |
4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.455 | |
4gdc | NDP | UDP-galactopyranose mutase | / | 0.455 | |
1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.454 | |
1txt | CAA | HMG-CoA synthase | / | 0.454 | |
2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.454 | |
2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.454 | |
3a78 | 3EV | Vitamin D3 receptor | / | 0.454 | |
3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.454 | |
3w0g | W07 | Vitamin D3 receptor | / | 0.454 | |
4elb | 34R | Dihydrofolate reductase | / | 0.454 | |
4itf | TFY | Vitamin D3 receptor | / | 0.454 | |
4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.454 | |
1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.453 | |
1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.453 | |
2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.453 | |
2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
2hc4 | VDX | Vitamin D3 receptor A | / | 0.453 | |
2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
3b70 | NAP | Enoyl reductase LovC | 1 | 0.453 | |
3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.453 | |
3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.453 | |
3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.453 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.453 | |
4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.453 | |
5bp9 | SAH | Putative methyltransferase protein | / | 0.453 | |
1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
1r2j | FAD | FkbI | / | 0.452 | |
1s0z | EB1 | Vitamin D3 receptor | / | 0.452 | |
1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
1zdw | FLV | Prenyltransferase | / | 0.452 | |
1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.452 | |
2h6i | CYS_VAL_LEU_SER_GER | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
2xvv | 9DN | Serum albumin | / | 0.452 | |
3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
3ebf | 332 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.452 | |
3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.452 | |
1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.451 | |
1rd4 | L08 | Integrin alpha-L | / | 0.451 | |
2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.451 | |
3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
3w5r | LOA | Vitamin D3 receptor | / | 0.451 | |
4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.451 | |
4e2b | FMN | Dehydrogenase | / | 0.451 | |
4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.451 | |
4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
3pwh | ZMA | Adenosine receptor A2a | / | 0.451 | |
1ie9 | VDX | Vitamin D3 receptor | / | 0.450 | |
1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.450 | |
1qor | NDP | Quinone oxidoreductase 1 | / | 0.450 | |
2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.450 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.450 | |
2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
3f63 | GTX | Glutathione transferase GST1-4 | / | 0.450 | |
3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.450 | |
4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.450 | |
4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.450 | |
4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.450 | |
5k2a | ZMA | Adenosine receptor A2a | / | 0.450 | |
5k2d | ZMA | Adenosine receptor A2a | / | 0.450 | |
1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.449 | |
1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
1kqw | RTL | Cellular retinol-binding protein type II | / | 0.449 | |
1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.449 | |
1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.449 | |
1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
2tps | TPS | Thiamine-phosphate synthase | / | 0.449 | |
2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.449 | |
3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
3kr5 | BEY | M17 leucyl aminopeptidase | / | 0.449 | |
3lu8 | IQX | Serum albumin | / | 0.449 | |
3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.449 | |
3up0 | D7S | aceDAF-12 | / | 0.449 | |
3vqs | JT1 | Genome polyprotein | / | 0.449 | |
4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.449 | |
4jau | ADP | Sensor histidine kinase | / | 0.449 | |
4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.449 | |
5k2c | ZMA | Adenosine receptor A2a | / | 0.449 | |
1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.448 | |
1x8l | OXR | Retinol dehydratase | / | 0.448 | |
2i4q | UA4 | Renin | 3.4.23.15 | 0.448 | |
2vfz | UPF | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.448 | |
2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
3g72 | A6T | Renin | 3.4.23.15 | 0.448 | |
3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.448 | |
4b1f | KRH | Glutamate racemase | / | 0.448 | |
4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.448 | |
4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.448 | |
4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.448 | |
1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.447 | |
1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.447 | |
1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.447 | |
1rk3 | VDX | Vitamin D3 receptor | / | 0.447 | |
2g1s | 4IG | Renin | 3.4.23.15 | 0.447 | |
2ham | C33 | Vitamin D3 receptor | / | 0.447 | |
2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.447 | |
2zlc | VDX | Vitamin D3 receptor | / | 0.447 | |
3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.447 | |
3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
4r81 | FMN | Predicted NADH dehydrogenase | / | 0.447 | |
5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.447 | |
1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.446 | |
1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
1ykd | CMP | Adenylate cyclase | / | 0.446 | |
2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.446 | |
2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.446 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
2o4r | VD5 | Vitamin D3 receptor | / | 0.446 | |
2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.446 | |
2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
2z3u | CRR | Cytochrome P450 | / | 0.446 | |
3b6z | CO7 | Enoyl reductase LovC | 1 | 0.446 | |
3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
3e6o | A55 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.446 | |
3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.446 | |
3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.446 | |
3oqf | S51 | Renin | 3.4.23.15 | 0.446 | |
3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
3tjz | GNP | ADP-ribosylation factor 1 | / | 0.446 | |
3w0a | DS5 | Vitamin D3 receptor | / | 0.446 | |
4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.446 | |
4e2d | FMN | Dehydrogenase | / | 0.446 | |
4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
4jnm | 1LJ | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.446 | |
4yek | THM | Thymidine phosphorylase | / | 0.446 | |
1f5f | DHT | Sex hormone-binding globulin | / | 0.445 | |
1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
1ppj | ANY | Cytochrome b | / | 0.445 | |
1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.445 | |
2lba | CHO | Fatty acid binding protein 6 | / | 0.445 | |
2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.445 | |
2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.445 | |
3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.445 | |
3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.445 | |
4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.445 | |
4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
4ite | TEY | Vitamin D3 receptor | / | 0.445 | |
4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.445 | |
4lsj | LSJ | Glucocorticoid receptor | / | 0.445 | |
3eml | ZMA | Adenosine receptor A2a | / | 0.445 | |
1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
1d2s | DHT | Sex hormone-binding globulin | / | 0.444 | |
1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.444 | |
1osv | CHC | Bile acid receptor | / | 0.444 | |
2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.444 | |
2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.444 | |
2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.444 | |
3ibq | ATP | Pyridoxal kinase | / | 0.444 | |
3m31 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.444 | |
3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.444 | |
3svj | 4LI | Peptide deformylase | / | 0.444 | |
3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.444 | |
3tqh | NDP | Quinone oxidoreductase | / | 0.444 | |
3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
3vrt | YS2 | Vitamin D3 receptor | / | 0.444 | |
3vrv | YSD | Vitamin D3 receptor | / | 0.444 | |
3w5p | 4OA | Vitamin D3 receptor | / | 0.444 | |
4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.444 | |
4ejv | LCL | Transcriptional regulator TcaR | / | 0.444 | |
4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.444 | |
4jr5 | 1LS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.444 | |
4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
4o28 | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.444 | |
4ynt | FDA | Glucose oxidase, putative | / | 0.444 | |
5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
1b87 | ACO | Aac(6')-Ii protein | / | 0.443 | |
1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.443 | |
1g6o | ADP | Cag alpha | / | 0.443 | |
1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.443 | |
1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.443 | |
1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.443 | |
2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
2jfa | RAL | Estrogen receptor | / | 0.443 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
2xyt | TC9 | Soluble acetylcholine receptor | / | 0.443 | |
2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.443 | |
3ix3 | OHN | Transcriptional activator protein LasR | / | 0.443 | |
3mla | JJZ | Probable nicotinate-nucleotide adenylyltransferase | / | 0.443 | |
3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
3nju | ANN | Acidic phospholipase A2 3 | 3.1.1.4 | 0.443 | |
3own | 3OX | Renin | 3.4.23.15 | 0.443 | |
3vt3 | VDX | Vitamin D3 receptor | / | 0.443 | |
3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
4au7 | SAH | Histone-lysine N-methyltransferase KMT5C | 2.1.1.43 | 0.443 | |
4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.443 | |
4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.443 | |
4o2b | LOC | Tubulin beta-2B chain | / | 0.443 | |
4q71 | FAD | Bifunctional protein PutA | / | 0.443 | |
4zm3 | PLP | Aminotransferase | / | 0.443 | |
1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.442 | |
1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.442 | |
1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
1lbc | CYZ | Glutamate receptor 2 | / | 0.442 | |
1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.442 | |
1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.442 | |
1y4s | ADP | Chaperone protein HtpG | / | 0.442 | |
2ejz | SAH | Diphthine synthase | / | 0.442 | |
2g20 | L1A | Renin | 3.4.23.15 | 0.442 | |
2iko | 7IG | Renin | 3.4.23.15 | 0.442 | |
2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
2wd8 | VGF | Pteridine reductase | / | 0.442 | |
2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
3kpz | ZNE | Vitamin D3 receptor | / | 0.442 | |
3n62 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
3oqk | S52 | Renin | 3.4.23.15 | 0.442 | |
3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
4b4w | 9L9 | Bifunctional protein FolD | / | 0.442 | |
4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
4n1g | CEI | Obelin | / | 0.442 | |
4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.442 | |
4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
5kgh | ACO | Predicted acetyltransferase | / | 0.442 | |
1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.441 | |
1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.441 | |
2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
2hcd | BIV | Vitamin D3 receptor A | / | 0.441 | |
2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.441 | |
3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.441 | |
3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
3ixp | 834 | Ecdysone receptor | / | 0.441 | |
3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
4fhh | 0U3 | Vitamin D3 receptor A | / | 0.441 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.441 | |
4ia1 | BIV | Vitamin D3 receptor A | / | 0.441 | |
4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.441 | |
4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.441 | |
4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1kzj | CB3 | Thymidylate synthase | / | 0.440 | |
1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
1s19 | MC9 | Vitamin D3 receptor | / | 0.440 | |
1v35 | NAI | Enoyl-ACP reductase | / | 0.440 | |
1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
2bkt | RPF | Renin | 3.4.23.15 | 0.440 | |
2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.440 | |
2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 | |
2wzy | SQX | Soluble acetylcholine receptor | / | 0.440 | |
2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.440 | |
3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.440 | |
3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
3tox | NAP | Putative oxidoreductase | / | 0.440 | |
3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
4j6c | STR | Cytochrome P450 monooxygenase | / | 0.440 | |
4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.440 | |
4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.440 | |
4nie | NBH | Nuclear receptor ROR-gamma | / | 0.440 | |
4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.440 | |
5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 |