sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4r87 | COA | Spermidine N(1)-acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 1.000 | |
| 4r57 | ACO | Spermidine N(1)-acetyltransferase | / | 0.545 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.521 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.514 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.475 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.469 | |
| 3sxn | COA | N-acetyltransferase Eis | / | 0.469 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.467 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.463 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.462 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.462 | |
| 3ryo | ACO | N-acetyltransferase Eis | / | 0.460 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.455 | |
| 4jxr | ACO | Acetyltransferase | / | 0.455 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.451 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.446 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.446 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.445 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.444 | |
| 1yre | COA | Uncharacterized protein | / | 0.443 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.443 | |
| 1s7l | COA | Acetyl transferase | / | 0.442 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 |