Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4r6xSAHPhosphoethanolamine N-methyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4r6xSAHPhosphoethanolamine N-methyltransferase/1.000
3uj7SAMPhosphoethanolamine N-methyltransferase/0.650
3uj8SFGPhosphoethanolamine N-methyltransferase/0.592
4iv0SAMPhosphoethanolamine N-methyltransferase, putative/0.583
4fgzSAHPhosphoethanolamine N-methyltransferase/0.555
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.553
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.499
5je3SAHMethyl transferase/0.490
5je2SAHMethyl transferase/0.478
3bgvSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.473
5je4SAHMethyl transferase/0.472
3ha7B32Hydroxymycolate synthase MmaA42.1.10.467
3p9kSAHCaffeic acid O-methyltransferase/0.464
4krhSAMPhosphoethanolamine N-methyltransferase 2/0.461
3ou6SAMSAM-dependent methyltransferase/0.457
4iv8SAMPhosphoethanolamine N-methyltransferase,putative/0.457
4qtuSAM18S rRNA (guanine(1575)-N(7))-methyltransferase/0.457
1ve3SAMUncharacterized protein/0.453
3ha5SFGHydroxymycolate synthase MmaA42.1.10.453
3busSAHDemethylrebeccamycin-D-glucose O-methyltransferase/0.452
2z1mNDPGDP-mannose 4,6-dehydratase/0.449
3reoSAH(Iso)eugenol O-methyltransferase2.1.1.1460.449
5bp7SAHSAM-dependent methyltransferase/0.449
3kxw1ZZSaframycin Mx1 synthetase B/0.448
5epeSAHUncharacterized protein/0.448
3ha3SAHHydroxymycolate synthase MmaA42.1.10.447
3ou7SAMSAM-dependent methyltransferase/0.443
5icfSAH(S)-norcoclaurine 6-O-methyltransferase/0.443
1kphSAHCyclopropane mycolic acid synthase 12.1.1.790.442
5jr3SAHCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.442
2a14SAHIndolethylamine N-methyltransferase2.1.1.490.440