sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4qjl | COA | Phosphopantetheinyl transferase, PptII |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4qjl | COA | Phosphopantetheinyl transferase, PptII | / | 1.000 | |
| 4qjk | COA | Phosphopantetheinyl transferase PptT (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase) | / | 0.548 | |
| 4qvh | COA | Phosphopantetheinyl transferase PptT (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase) | / | 0.542 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.482 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.472 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4j0y | 1H6 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.461 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.458 | |
| 3b9l | AZZ | Serum albumin | / | 0.457 | |
| 4oaq | NDP | R-specific carbonyl reductase | / | 0.457 | |
| 3pxv | FMN | Nitroreductase | / | 0.456 | |
| 3tfp | 03L | Dehydrosqualene synthase | / | 0.453 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.452 | |
| 2xvw | 9NR | Serum albumin | / | 0.450 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.449 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3qdl | FMN | Oxygen-insensitive NADPH nitroreductase | / | 0.449 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3dl0 | AP5 | Adenylate kinase | / | 0.448 | |
| 4j0p | 1H8 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.447 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.446 | |
| 3suf | SUE | Polyprotein | / | 0.446 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 1kqd | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.444 | |
| 4j17 | 1HQ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 2wow | NDP | Trypanothione reductase | / | 0.443 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 4la0 | 198 | Serum albumin | / | 0.443 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.443 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.442 | |
| 4j1f | 1HL | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.441 | |
| 4yal | 2AM | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4j1c | 1HO | Beta-secretase 1 | 3.4.23.46 | 0.440 |