scPDB - Distribution of Binding site Similarity values of 4qfx entry / Site 6

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4qfx	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4qfx	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	1.000
4bzb	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.596
4to2	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.518
4qfz	TTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.501
4to3	DCP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.500
4qg0	DUT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.497
4tnz	TTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.474
4qfy	DCP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.473
4to4	DCP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.467
4qg1	DTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.461
4to6	TTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.455
4rxq	DUT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.444
4rxr	DCP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.444
4zwe	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.442