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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4q93STLTyrosine--tRNA ligase, cytoplasmic6.1.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4q93STLTyrosine--tRNA ligase, cytoplasmic6.1.1.11.000
4ey6GNTAcetylcholinesterase3.1.1.70.527
2rlcCHDCholoylglycine hydrolase3.5.1.240.495
2ed3SAHDiphthine synthase/0.494
2on6IMHPurine nucleoside phosphorylase2.4.2.10.492
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.491
1obnASVIsopenicillin N synthase1.21.3.10.488
2ejzSAHDiphthine synthase/0.488
4xymCOAAcyl-CoA synthetase (NDP forming)/0.487
1xddAAYIntegrin alpha-L/0.484
2cmoM1LGlutamate receptor 2/0.484
3hk1B64Fatty acid-binding protein, adipocyte/0.484
3zkyWT4Isopenicillin N synthase1.21.3.10.484
2ek3SAHDiphthine synthase/0.482
3fp0FP015-O-acetyltransferase/0.482
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.481
3sl2ATPSensor histidine kinase WalK/0.481
3wv9FEGHmd co-occurring protein HcgE/0.480
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.479
4a802ANMajor pollen allergen Bet v 1-A/0.479
1qjfACSIsopenicillin N synthase1.21.3.10.478
2g1n1IGRenin3.4.23.150.478
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.478
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.476
2axnADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3/0.475
2i7nACOPantothenate kinase 12.7.1.330.475
3gwfNAPCyclohexanone monooxygenase/0.475
4tx9AMZPhosphoribosyl isomerase A/0.475
2yig5ELCollagenase 33.4.240.474
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.473
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.473
3qeoLLTDeoxycytidine kinase2.7.1.740.473
5jjsSAHGenome polyprotein/0.473
1rfuADPPyridoxal kinase2.7.1.350.472
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.472
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.472
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
1cqp803Integrin alpha-L/0.471
2e15SAHDiphthine synthase/0.471
2g1y5IGRenin3.4.23.150.471
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.471
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.471
3clrFADElectron transfer flavoprotein subunit alpha/0.470
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.469
2owkSAHDiphthine synthase/0.469
4xr9NADCalS8/0.469
1b2lNDCAlcohol dehydrogenase1.1.1.10.468
1o97FADElectron transfer flavoprotein subunit alpha/0.467
2oegUPGUDP-glucose pyrophosphorylase/0.467
2v5aLZLBiotin carboxylase6.3.4.140.467
4cdmFO1Deoxyribodipyrimidine photolyase/0.467
4gxs0YSGlutamate receptor 2/0.467
4s1iPLPPyridoxal kinase, putative/0.467
3fr28CAFatty acid-binding protein, adipocyte/0.466
4a862ANMajor pollen allergen Bet v 1-A/0.466
4b4w9L9Bifunctional protein FolD/0.466
4yjdFADD-amino-acid oxidase1.4.3.30.466
1cnfFADNitrate reductase [NADH]1.7.1.10.465
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.465
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.465
1pwuGM6Lethal factor3.4.24.830.465
2emuSAHDiphthine synthase/0.465
2gjnFMNNitronate monooxygenase1.13.12.160.465
2w6qOA5Biotin carboxylase6.3.4.140.465
3nutSAHPrecorrin-3 methylase/0.465
4bfvZVVPantothenate kinase2.7.1.330.465
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.465
2g1r3IGRenin3.4.23.150.464
2gjlFMNNitronate monooxygenase1.13.12.160.464
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.464
3k8q22APurine nucleoside phosphorylase2.4.2.10.464
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.464
4u7wNDPMxaA/0.464
1m8gNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.463
1owe675Urokinase-type plasminogen activator3.4.21.730.463
2g21L1BRenin3.4.23.150.463
2huqSAHDiphthine synthase/0.463
2iviACWIsopenicillin N synthase1.21.3.10.463
2p2xSAHDiphthine synthase/0.463
2pcaSAHDiphthine synthase/0.463
2xpuTDCTetracycline repressor protein class D/0.463
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.463
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.463
1mewXMPInosine-5'-monophosphate dehydrogenase/0.462
1ppjANYCytochrome b/0.462
2c29NAPDihydroflavonol 4-reductase/0.462
2dsiSAHDiphthine synthase/0.462
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.462
2il2LIXRenin3.4.23.150.462
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.462
3hl4CDCCholine-phosphate cytidylyltransferase A/0.462
4i1nFOLDihydrofolate reductase1.5.1.30.462
1bk0ACVIsopenicillin N synthase1.21.3.10.461
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.461
1nytNAPShikimate dehydrogenase (NADP(+))/0.461
2hutSAHDiphthine synthase/0.461
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.461
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3w6hAZMCarbonic anhydrase 14.2.1.10.461
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.461
1f9aATPNicotinamide-nucleotide adenylyltransferase/0.460
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2v57PRLTetR family transcriptional regulator/0.460
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.460
3fr4F8AFatty acid-binding protein, adipocyte/0.460
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.460
4klaCHDFerrochelatase, mitochondrial4.99.1.10.460
4lxm1YUBeta-secretase 13.4.23.460.460
4zj8SUVOrexin receptor type 1/0.460
1g28FMNPHY3/0.459
1i59ANPChemotaxis protein CheA2.7.13.30.459
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.459
2dv7SAHDiphthine synthase/0.459
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.459
2v1aFMNNPH1-1/0.459
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.459
3aw9GDUNAD-dependent epimerase/dehydratase/0.459
3q9bB3NAcetylpolyamine amidohydrolase/0.459
4oztP1AEcdysone receptor, putative/0.459
4u0mGTPCyclic GMP-AMP synthase/0.459
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.459
3emlZMAAdenosine receptor A2a/0.459
1c7oPPGHemolysin/0.458
1d6w00RProthrombin3.4.21.50.458
1ra8FOLDihydrofolate reductase1.5.1.30.458
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.458
2pchSAHDiphthine synthase/0.458
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.458
2r8fAGSNon-structural protein 23.6.40.458
2v58LZJBiotin carboxylase6.3.4.140.458
2y3sTIRTamL/0.458
2yoj8Y6Genome polyprotein2.7.7.480.458
2z6rSAHDiphthine synthase/0.458
2zbaZBATrichothecene 3-O-acetyltransferase/0.458
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3x2fNAIAdenosylhomocysteinase/0.458
4xguADPPutative pachytene checkpoint protein 2/0.458
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.458
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.457
1sq5ADPPantothenate kinase2.7.1.330.457
2ab8MTPAdenosine kinase2.7.1.200.457
2dekSAHDiphthine synthase/0.457
2eh4SAHDiphthine synthase/0.457
2ekaSAHDiphthine synthase/0.457
2g78REACellular retinoic acid-binding protein 2/0.457
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4twnB96Ephrin type-A receptor 32.7.10.10.457
5esdTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.457
1ia4TQ6Dihydrofolate reductase1.5.1.30.456
1qm5PLPMaltodextrin phosphorylase2.4.1.10.456
2owgSAHDiphthine synthase/0.456
2uxoTACHTH-type transcriptional regulator TtgR/0.456
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.456
3h3r14HCollagen type IV alpha-3-binding protein/0.456
4b4vL34Bifunctional protein FolD/0.456
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
1gpnHUBAcetylcholinesterase3.1.1.70.455
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
1pd9CO4Dihydrofolate reductase1.5.1.30.455
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.455
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.455
2e17SAHDiphthine synthase/0.455
2g247IGRenin3.4.23.150.455
2huvSAHDiphthine synthase/0.455
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.455
2pb6SAHDiphthine synthase/0.455
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.455
3eldSFGMethyltransferase/0.455
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.455
3oqfS51Renin3.4.23.150.455
3thyADPDNA mismatch repair protein Msh2/0.455
3uylTYDProbable NDP-rhamnosyltransferase/0.455
4bb3KKAIsopenicillin N synthase1.21.3.10.455
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.454
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.454
1g1aNADdTDP-glucose 4,6-dehydratase/0.454
1qorNDPQuinone oxidoreductase 1/0.454
1u71MXADihydrofolate reductase1.5.1.30.454
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2bjfDXCCholoylglycine hydrolase3.5.1.240.454
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.454
2pg0FADAcyl-CoA dehydrogenase/0.454
2w6pOA4Biotin carboxylase6.3.4.140.454
2wpxACOOrf14/0.454
2x0eTYDWsaF/0.454
3cluFADElectron transfer flavoprotein subunit alpha/0.454
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.454
2c3cNAP2-oxopropyl-CoM reductase, carboxylating1.8.1.50.453
2e4nSAHDiphthine synthase/0.453
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.453
2p9dSAHDiphthine synthase/0.453
2pb4SAHDiphthine synthase/0.453
3adaNADSubunit alpha of sarocosine oxidase/0.453
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.453
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.453
4i1c1BEBeta-secretase 13.4.23.460.453
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.453
4xqcNADHomospermidine synthase2.5.1.440.453
5fa1C5PPutative N-acetyl glucosaminyl transferase/0.453
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.452
1txtCAAHMG-CoA synthase/0.452
2e16SAHDiphthine synthase/0.452
2emrSAHDiphthine synthase/0.452
2i4qUA4Renin3.4.23.150.452
3gbuATPUncharacterized sugar kinase PH14592.7.10.452
3m6pBB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.452
4e9aQAPPeptide deformylase/0.452
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.452
1ek5NADUDP-glucose 4-epimerase/0.451
1hb3SCVIsopenicillin N synthase1.21.3.10.451
1pqc444Oxysterols receptor LXR-beta/0.451
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.451
1ut6A8NAcetylcholinesterase3.1.1.70.451
2ea2F77Methionine aminopeptidase 2/0.451
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.451
2pckSAHDiphthine synthase/0.451
2pncCLUPrimary amine oxidase, liver isozyme/0.451
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.451
2qn3F55Glycogen phosphorylase, muscle form2.4.1.10.451
2vbdV10Isopenicillin N synthase1.21.3.10.451
3h3t16HCollagen type IV alpha-3-binding protein/0.451
3kemIPE4-hydroxy-3-methylbut-2-enyl diphosphate reductase/0.451
3oafOAGDihydrofolate reductase1.5.1.30.451
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
3p62FMNPentaerythritol tetranitrate reductase/0.451
4iarERM5-hydroxytryptamine receptor 1B/0.451
4j3mAJ8Tankyrase-22.4.2.300.451
4jq4IMNAldo-keto reductase family 1 member C2/0.451
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1cs4FOKAdenylate cyclase type 2/0.450
1cs4FOKAdenylate cyclase type 5/0.450
1dr2TAPDihydrofolate reductase1.5.1.30.450
1jdvADNPurine nucleoside phosphorylase/0.450
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.450
1votHUPAcetylcholinesterase3.1.1.70.450
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.450
2eldSAHDiphthine synthase/0.450
2owfSAHDiphthine synthase/0.450
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.450
2xtnGTPGTPase IMAP family member 2/0.450
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
3fr5I4AFatty acid-binding protein, adipocyte/0.450
3mauPLRPutative sphingosine-1-phosphate lyase/0.450
3nz2ACOHexapeptide-repeat containing-acetyltransferase/0.450
3oqkS52Renin3.4.23.150.450
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
4b1rITCTetracycline repressor protein class D/0.450
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.450
4i0j842Beta-secretase 13.4.23.460.450
4p9dTMPDeoxycytidylate deaminase/0.450
4stdBFSScytalone dehydratase4.2.1.940.450
4xbfFADLysine-specific histone demethylase 1A10.450
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.449
1qtiGNTAcetylcholinesterase3.1.1.70.449
2x3fAPCPantothenate synthetase/0.449
3gep24HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.449
3gnvXNZGenome polyprotein2.7.7.480.449
3h3qH13Collagen type IV alpha-3-binding protein/0.449
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.449
3p0fBAUUridine phosphorylase 22.4.2.30.449
3phjDHKShikimate dehydrogenase (NADP(+))/0.449
4a5lFADThioredoxin reductase/0.449
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.449
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.449
4cukNAID-lactate dehydrogenase/0.449
4hsuFADLysine-specific histone demethylase 1B10.449
4uocNCNCinA-like protein/0.449
4zhiADPKinesin-like protein KIF11/0.449
1i59ADPChemotaxis protein CheA2.7.13.30.448
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.448
1qrsATPGlutamine--tRNA ligase6.1.1.180.448
1rctNOSPurine nucleoside phosphorylase2.4.2.10.448
2a84ATPPantothenate synthetase6.3.2.10.448
2dv5SAHDiphthine synthase/0.448
2el3SAHDiphthine synthase/0.448
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2rqfJH3Hemolymph juvenile hormone binding protein/0.448
2wo7ASVIsopenicillin N synthase1.21.3.10.448
3ekuCY9Actin-5C/0.448
3elySAHMethyltransferase/0.448
3ig6438Urokinase-type plasminogen activator3.4.21.730.448
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
3pdqKC6Lysine-specific demethylase 4A1.14.110.448
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.448
4rww2BALmo2692 protein/0.448
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.448
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.447
1dhfFOLDihydrofolate reductase1.5.1.30.447
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.447
1n2hPAJPantothenate synthetase6.3.2.10.447
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.447
1nenDNTSuccinate dehydrogenase iron-sulfur subunit1.3.5.10.447
1nenDNTSuccinate dehydrogenase cytochrome b556 subunit/0.447
1rx7FOLDihydrofolate reductase1.5.1.30.447
1x1aSAMC-20 methyltransferase/0.447
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.447
2abaSTRPentaerythritol tetranitrate reductase/0.447
2hfuMEVMevalonate kinase/0.447
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.447
2os1BB2Peptide deformylase/0.447
3eksCY9Actin-5C/0.447
3g2hKOTGlycogen phosphorylase, muscle form2.4.1.10.447
3uph0C1Genome polyprotein2.7.7.480.447
4bfwZVWPantothenate kinase2.7.1.330.447
4ohwATPProtein clpf-1/0.447
4tjy3GNTankyrase-22.4.2.300.447
1afeALZProthrombin3.4.21.50.446
1ej2NADNicotinamide-nucleotide adenylyltransferase2.7.7.10.446
1geeNADGlucose 1-dehydrogenase1.1.1.470.446
1rneC60Renin3.4.23.150.446
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.446
1w7h3IPMitogen-activated protein kinase 14/0.446
1yryMSGPurine nucleoside phosphorylase2.4.2.10.446
2dshSAHDiphthine synthase/0.446
2ek2SAHDiphthine synthase/0.446
2g1o2IGRenin3.4.23.150.446
2w02ATPAcsD/0.446
3b9oFMNAlkane monoxygenase/0.446
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.446
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.446
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.446
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.446
3otwCOAPhosphopantetheine adenylyltransferase/0.446
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
4g95OAGDihydrofolate reductase1.5.1.30.446
4qtnNNRNicotinamide riboside transporter PnuC/0.446
4qxq1YEStimulator of interferon genes protein/0.446
4tvbNADHomospermidine synthase2.5.1.440.446
5e9eANPMyosin heavy chain kinase A2.7.11.70.446
1je1GMPPurine nucleoside phosphorylase/0.445
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.445
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.445
2dxwSAHDiphthine synthase/0.445
2p6lSAHDiphthine synthase/0.445
2rd2QSIGlutamine--tRNA ligase6.1.1.180.445
2re8GSUGlutamine--tRNA ligase6.1.1.180.445
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.445
3uk6ADPRuvB-like 23.6.4.120.445
4bis8HQLysine-specific demethylase 4A1.14.110.445
4l4eCAMCamphor 5-monooxygenase1.14.15.10.445
4q71FADBifunctional protein PutA/0.445
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.445
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.445
3qakUKAAdenosine receptor A2a/0.445
1dr3HBIDihydrofolate reductase1.5.1.30.444
1g6oADPCag alpha/0.444
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.444
1rszDIHPurine nucleoside phosphorylase2.4.2.10.444
1toiHCIAspartate aminotransferase2.6.1.10.444
1vceSAHDiphthine synthase/0.444
2e0nSAHPrecorrin-2 C20-methyltransferase/0.444
2g1s4IGRenin3.4.23.150.444
2oz57XYUncharacterized protein/0.444
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.444
3co93MSGenome polyprotein2.7.7.480.444
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3kpbSAMUncharacterized protein MJ0100/0.444
3nmpPYVAbscisic acid receptor PYL2/0.444
4dptAGSMevalonate diphosphate decarboxylase/0.444
4jc51K5Stimulator of interferon genes protein/0.444
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.444
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.444
4xz3COAAcyl-CoA synthetase (NDP forming)/0.444
4zolGTPTubulin alpha-1B chain/0.444
5eccNAPDehydrofolate reductase type I/0.444
4xnw2IDP2Y purinoceptor 1/0.444
1bim0QBRenin3.4.23.150.443
1df7MTXDihydrofolate reductase1.5.1.30.443
1dx6GNTAcetylcholinesterase3.1.1.70.443
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.443
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.443
1xtrGNPGTP-binding protein Rheb/0.443
1z71L17Prothrombin3.4.21.50.443
2dv3SAHDiphthine synthase/0.443
2dwpACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.443
2egsSAHDiphthine synthase/0.443
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2h94FADLysine-specific histone demethylase 1A10.443
2p5cSAHDiphthine synthase/0.443
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.443
2trsPLSTryptophan synthase beta chain4.2.1.200.443
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.443
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.443
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.443
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.443
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.443
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.443
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.443
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.443
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.443
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.443
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.443
1culFOKAdenylate cyclase type 2/0.442
1culFOKAdenylate cyclase type 5/0.442
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.442
1hfqMOTDihydrofolate reductase1.5.1.30.442
1j9zFADNADPH--cytochrome P450 reductase/0.442
1yqzCOACoenzyme A disulfide reductase/0.442
2eh5SAHDiphthine synthase/0.442
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.442
2i7pACOPantothenate kinase 32.7.1.330.442
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2vn0TDZCytochrome P450 2C8/0.442
2yj4ATPCopper-transporting ATPase/0.442
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3cb2GDPTubulin gamma-1 chain/0.442
3cgbCOACoenzyme A disulfide reductase/0.442
3clsFADElectron transfer flavoprotein subunit alpha/0.442
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.442
3d4bDZDNAD-dependent protein deacetylase/0.442
3er93ATPoly(A) polymerase catalytic subunit2.7.7.190.442
3h4vDVPPteridine reductase 11.5.1.330.442
3isjA8DPantothenate synthetase6.3.2.10.442
3pxyJWSCyclin-dependent kinase 22.7.11.220.442
3ska053Genome polyprotein2.7.7.480.442
3tm5SFGUncharacterized protein/0.442
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.442
4jxxATPGlutamine--tRNA ligase6.1.1.180.442
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.442
4zk6NTMQuinolinate synthase A/0.442
5dn1AMZPhosphoribosyl isomerase A5.3.1.160.442
5ej5TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.442
1adfTADAlcohol dehydrogenase E chain1.1.1.10.441
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.441
1e66HUXAcetylcholinesterase3.1.1.70.441
1hdoNAPFlavin reductase (NADPH)/0.441
1kzjCB3Thymidylate synthase/0.441
1lb9DNQGlutamate receptor 2/0.441
1n3sGTPGTP cyclohydrolase 13.5.4.160.441
1nm6L86Prothrombin3.4.21.50.441
1rzuADPGlycogen synthase 12.4.1.210.441
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.441
2e8qSAHDiphthine synthase/0.441
2ew5Y12Peptide deformylase/0.441
2fzwNADAlcohol dehydrogenase class-31.1.1.10.441
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.441
2p6kSAHDiphthine synthase/0.441
2pcgSAHDiphthine synthase/0.441
2qw034Z4-chlorobenzoyl CoA ligase/0.441
2zvbSAHPrecorrin-3 C17-methyltransferase/0.441
3b1pNOSPfkB carbohydrate kinase family protein/0.441
3d7zGK5Mitogen-activated protein kinase 14/0.441
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.441
3p3zP3ZPutative cytochrome P450/0.441
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.441
3zhbNAPPutative dehydrogenase/0.441
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.441
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.441
4fqsLYAThymidylate synthase ThyA/0.441
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.441
4j1k1HGBeta-secretase 13.4.23.460.441
4jjiNADAlcohol dehydrogenase class-3/0.441
4jlk1NODeoxycytidine kinase2.7.1.740.441
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.441
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.441
4kgkGTPUncharacterized protein/0.441
4mlp2CXCryptochrome-2/0.441
4okkU5P3'-5' exoribonuclease MT2234.1/0.441
4u0zAPCAdenosine monophosphate-protein transferase FICD2.7.7.n10.441
5ejaTD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.441
5esoTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.441
1cjvFOKAdenylate cyclase type 2/0.440
1cjvFOKAdenylate cyclase type 5/0.440
1dhrNADDihydropteridine reductase1.5.1.340.440
1dljUGAUDP-glucose 6-dehydrogenase/0.440
1mczRMNBenzoylformate decarboxylase4.1.1.70.440
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
1rftPXMPyridoxal kinase2.7.1.350.440
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.440
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.440
1xp8AGSProtein RecA/0.440
1yw8A75Methionine aminopeptidase 2/0.440
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.440
2e8rSAHDiphthine synthase/0.440
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.440
2qs1UB1Glutamate receptor ionotropic, kainate 1/0.440
2xvfFADPutative flavin-containing monooxygenase/0.440
2y60M8FIsopenicillin N synthase1.21.3.10.440
2y65ADPKinesin heavy chain/0.440
3aosJH2Hemolymph juvenile hormone binding protein/0.440
3c35KAIGlutamate receptor ionotropic, kainate 1/0.440
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3jzdNADMaleylacetate reductase/0.440
3po6DT9Carbonic anhydrase 24.2.1.10.440
3raiX85Cyclin-dependent kinase 22.7.11.220.440
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.440
4bfxZVXPantothenate kinase2.7.1.330.440
4bj9UHBTankyrase-22.4.2.300.440
4ef4C2EStimulator of interferon genes protein/0.440
4plpNADHomospermidine synthase2.5.1.440.440
4rp8ASCAscorbate-specific PTS system EIIC component/0.440
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.440