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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4q23RISFarnesyl pyrophosphate synthase2.5.1.10

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4q23RISFarnesyl pyrophosphate synthase2.5.1.101.000
3ldwZOLFarnesyl pyrophosphate synthase, putative/0.526
4nkeRISFarnesyl pyrophosphate synthase2.5.1.100.507
1yv5RISFarnesyl pyrophosphate synthase2.5.1.100.506
1yq7RISFarnesyl pyrophosphate synthase2.5.1.100.495
2f94BFQFarnesyl pyrophosphate synthase2.5.1.100.491
4lfvYS4Farnesyl pyrophosphate synthase2.5.1.100.476
3rbmB73Farnesyl pyrophosphate synthase, putative/0.474
2i191BYFarnesyl pyrophosphate synthase/0.472