Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ptfDCPDNA polymerase epsilon catalytic subunit A2.7.7.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ptfDCPDNA polymerase epsilon catalytic subunit A2.7.7.71.000
4fjlDGTDNA-directed DNA polymerase/0.524
3supDCPDNA-directed DNA polymerase/0.522
4m3tATPDNA-directed DNA polymerase/0.516
4m3xATPDNA-directed DNA polymerase/0.516
4dtpDGTDNA-directed DNA polymerase/0.507
4dtjTTPDNA-directed DNA polymerase/0.506
3ne6DCPDNA-directed DNA polymerase/0.504
4fjjTTPDNA-directed DNA polymerase/0.503
4m42ATPDNA-directed DNA polymerase/0.497
3lzjCTPDNA-directed DNA polymerase/0.487
4fjmDCPDNA-directed DNA polymerase/0.484
4fk4DGTDNA-directed DNA polymerase/0.478
4dtmDCPDNA-directed DNA polymerase/0.469
4fj5DTPDNA-directed DNA polymerase/0.456
4dtxTTPDNA-directed DNA polymerase/0.448