Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4pkwGM6Lethal factor3.4.24.83

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4pkwGM6Lethal factor3.4.24.831.000
1pkfEPDEpothilone C/D epoxidase1.140.479
2rqfJH3Hemolymph juvenile hormone binding protein/0.469
1vrwNAIEnoyl-ACP reductase/0.460
3p3zP3ZPutative cytochrome P450/0.460
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1q5dEPBEpothilone C/D epoxidase1.140.453
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2ejzSAHDiphthine synthase/0.449
4r20AERCytochrome P450 family 17 polypeptide 2/0.449
1cqp803Integrin alpha-L/0.448
5hs1VORLanosterol 14-alpha demethylase/0.448
4uymVOR14-alpha sterol demethylase Cyp51B/0.447
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3p99LNPLanosterol 14-alpha-demethylase/0.446
4bj9UHBTankyrase-22.4.2.300.446
4jbtASDCytochrome P450 monooxygenase/0.446
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.445
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
1rd4L08Integrin alpha-L/0.444
1zg32HIIsoflavone 4'-O-methyltransferase/0.444
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.443
3t3q9PLCytochrome P450 2A61.14.130.443
3wv9FEGHmd co-occurring protein HcgE/0.443
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.442
3aw9GDUNAD-dependent epimerase/dehydratase/0.441
4i13FOLDihydrofolate reductase1.5.1.30.441
4u7wNDPMxaA/0.441
1phgMYTCamphor 5-monooxygenase1.14.15.10.440
2ikuLIYRenin3.4.23.150.440
3br3ETHTH-type transcriptional regulator QacR/0.440
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.440