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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4pkgATPActin, alpha skeletal muscle

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4pkgATPActin, alpha skeletal muscle/1.000
1lotATPActin, alpha skeletal muscle/0.625
3m6gATPActin, alpha skeletal muscle/0.608
4k42ADPActin, alpha skeletal muscle/0.600
1t44ATPActin, alpha skeletal muscle/0.598
2q36ATPActin, alpha skeletal muscle/0.588
1s22ATPActin, alpha skeletal muscle/0.587
3tu5ATPActin, alpha skeletal muscle/0.579
3mn6ATPActin-5C/0.570
1h1vATPActin, alpha skeletal muscle/0.569
1rgiATPActin, alpha skeletal muscle/0.569
4pl8ATPActin, alpha skeletal muscle/0.569
4k41ATPActin, alpha skeletal muscle/0.564
5ce3ATPActin/0.560
3ffkATPActin, alpha skeletal muscle/0.557
4cbxATPActin-2/0.556
4pkhADPActin, alpha skeletal muscle/0.556
1c0fATPMajor actin/0.555
1qz5ATPActin, alpha skeletal muscle/0.548
3el2ATPActin-5C/0.545
4ci6ATPActin/0.545
1nmdATPMajor actin/0.543
3a5mATPMajor actin/0.543
4k43ADPActin, alpha skeletal muscle/0.540
1eqyATPActin, alpha skeletal muscle/0.534
3mn9ATPActin-5C/0.533
1mduATPActin, alpha skeletal muscle/0.530
1ijjATPActin, alpha skeletal muscle/0.529
2v51ATPActin, alpha skeletal muscle/0.529
2p9kATPActin-related protein 2/0.528
1kxpATPActin, alpha skeletal muscle/0.527
1nm1ATPMajor actin/0.526
3u9dATPActin, alpha skeletal muscle/0.526
1yxqATPActin, alpha skeletal muscle/0.518
3u4lATPActin, cytoplasmic 1/0.516
4jhdANPActin-5C/0.515
4m63ATPActin-5C/0.507
2q97ATPActin, alpha skeletal muscle/0.503
4rwtANPActin-5C/0.496
3mn7ATPActin-5C/0.495
3m1fATPActin, alpha skeletal muscle/0.491
4pkiATPActin, alpha skeletal muscle/0.487
2oanATPActin, cytoplasmic 1/0.481
3eksATPActin-5C/0.479
3dawATPActin, alpha skeletal muscle/0.475
3a5oATPMajor actin/0.474
3ekuATPActin-5C/0.464
2a41ATPActin, alpha skeletal muscle/0.455
3w3dATPActin, gamma-enteric smooth muscle/0.453
3uleATPActin-related protein 2/0.448
1dejATPMajor actin/0.444