sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 1.000 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.592 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.577 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.577 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.566 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.561 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.548 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.547 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.546 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.543 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.540 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.538 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.535 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.531 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.529 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.528 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.528 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.525 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.525 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.505 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.503 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.501 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.500 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.497 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.496 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.495 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.494 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.494 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.493 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.493 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.493 | |
| 3nbv | ANP | Ketohexokinase | / | 0.492 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.491 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.490 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.488 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.486 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.485 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.485 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.485 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.485 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.484 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.484 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.484 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.484 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.482 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.480 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.477 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.476 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.476 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.476 | |
| 2y00 | Y01 | Beta-1 adrenergic receptor | / | 0.475 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.475 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.475 | |
| 2c6h | PXI | Cytochrome P450 monooxygenase PikC | / | 0.473 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.472 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.471 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.470 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.470 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.470 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.470 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.470 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 1qvn | FRI | Interleukin-2 | / | 0.469 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.469 | |
| 4ema | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.467 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.467 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.467 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.466 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.466 | |
| 3q92 | XNB | Ketohexokinase | / | 0.466 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.465 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.465 | |
| 2y01 | Y01 | Beta-1 adrenergic receptor | / | 0.464 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.464 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 2hw1 | ANP | Ketohexokinase | / | 0.463 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.463 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.463 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 2y03 | Y01 | Beta-1 adrenergic receptor | / | 0.462 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.462 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.462 | |
| 1gqt | ACP | Ribokinase | / | 0.461 | |
| 3bva | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.461 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.461 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.461 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.460 | |
| 3qai | XNN | Ketohexokinase | / | 0.460 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.459 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.459 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.459 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.458 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.458 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.458 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.458 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.457 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2f3k | RO1 | Protease | / | 0.457 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.457 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.457 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.457 | |
| 4o8f | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.456 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3s3r | 0IW | Cathepsin B-like peptidase (C01 family) | / | 0.456 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.456 | |
| 4ye3 | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.456 | |
| 1osv | CHC | Bile acid receptor | / | 0.455 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.455 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.455 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.455 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.455 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 3dcr | KVS | Protease | / | 0.454 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.454 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.454 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.454 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.454 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.453 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.452 | |
| 2y02 | Y01 | Beta-1 adrenergic receptor | / | 0.452 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.452 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
| 3zux | TCH | Transporter | / | 0.452 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.452 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.452 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.451 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.451 | |
| 1ppj | ANY | Cytochrome b | / | 0.451 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.451 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 2idw | 017 | Protease | / | 0.451 | |
| 2w4i | VGA | Glutamate racemase | / | 0.451 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.451 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.451 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.451 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.451 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.451 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.451 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.450 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.450 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 5a3b | APR | SIR2 family protein | / | 0.450 | |
| 1n49 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.449 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.449 | |
| 3gco | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.449 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.449 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.449 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1ie4 | T44 | Transthyretin | / | 0.448 | |
| 2rkf | AB1 | Pol protein | / | 0.448 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.448 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 4c59 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.448 | |
| 4cta | ATP | CinA-like protein | / | 0.448 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.448 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.448 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.448 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 1ohr | 1UN | V-1 PROTEASE protein | / | 0.447 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.447 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 3tl9 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.447 | |
| 4idv | 13V | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.447 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.447 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.447 | |
| 4n6b | COA | Uncharacterized protein | / | 0.447 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.447 | |
| 1d4k | PI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.446 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.446 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 2q5k | AB1 | Protease | / | 0.446 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.446 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.446 | |
| 3i2l | 2NC | Protease | / | 0.446 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.446 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4icy | FAD | PgaE | / | 0.446 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.446 | |
| 1bvg | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.445 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.445 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.445 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3ggx | GGX | Gag-Pol polyprotein | / | 0.445 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.445 | |
| 3lu8 | IQX | Serum albumin | / | 0.445 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.445 | |
| 3ndx | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.445 | |
| 3zcw | 4A2 | Kinesin-like protein KIF11 | / | 0.445 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1ee0 | CAA | 2-pyrone synthase | / | 0.444 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.444 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.444 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.444 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.444 | |
| 2nnp | ROC | Protease | / | 0.444 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.444 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.444 | |
| 3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.444 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3upj | U03 | Gag-Pol polyprotein | / | 0.444 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.444 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.444 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.443 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.443 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.443 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.443 | |
| 2fdd | 385 | Pol protein | / | 0.443 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.443 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.443 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.443 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3i6o | GR6 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.443 | |
| 4j54 | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.442 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.442 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1hvj | A78 | Gag-Pol polyprotein | / | 0.442 | |
| 2qhc | AB1 | Protease | / | 0.442 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.442 | |
| 3gob | HXX | DdmC | / | 0.442 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3so9 | 017 | Pol protein | / | 0.442 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.442 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.442 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.442 | |
| 4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.442 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.442 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.442 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.442 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1ida | 0PO | Gag-Pol polyprotein | 3.4.23.47 | 0.441 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.441 | |
| 1nde | MON | Estrogen receptor beta | / | 0.441 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.441 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.441 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.441 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.441 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.441 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.441 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.441 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.441 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 3wxy | COA | Uncharacterized protein | / | 0.441 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.441 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.441 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.441 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 1mui | AB1 | Protease | / | 0.440 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2aid | THK | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.440 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.440 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.440 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3dck | KVI | Protease | / | 0.440 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.440 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.440 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.440 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.440 |