sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 1.000 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.553 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.526 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.525 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.510 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.503 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.498 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.497 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.495 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.490 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.488 | |
| 5dp2 | NAP | CurF | / | 0.488 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.486 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.486 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.486 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.484 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.484 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.483 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.481 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.481 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.480 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.480 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.480 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.477 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.477 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.477 | |
| 4l32 | 1VF | Tankyrase-2 | 2.4.2.30 | 0.477 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.476 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.476 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.474 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.472 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.471 | |
| 1c7o | PPG | Hemolysin | / | 0.470 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.470 | |
| 2giq | NN2 | Genome polyprotein | 2.7.7.48 | 0.470 | |
| 2ibu | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.470 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.469 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.469 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.469 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.469 | |
| 4bue | JQF | Tankyrase-2 | 2.4.2.30 | 0.469 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.469 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.468 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.468 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.468 | |
| 4bus | 32F | Tankyrase-2 | 2.4.2.30 | 0.468 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.467 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.467 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.467 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.467 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.466 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.466 | |
| 4buw | F33 | Tankyrase-2 | 2.4.2.30 | 0.466 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.466 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.466 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.465 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.465 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.465 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 4e2z | JHZ | Methyltransferase | / | 0.465 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.465 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.465 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.465 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.464 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.464 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.464 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.463 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.463 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.463 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.463 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.462 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.462 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.462 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.462 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.461 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.461 | |
| 3u4r | 08F | Genome polyprotein | 2.7.7.48 | 0.461 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.460 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.460 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.460 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.460 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.460 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.460 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.460 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.459 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.459 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.459 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4eaw | 0NQ | Genome polyprotein | 2.7.7.48 | 0.459 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.459 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2uyw | BTN | Avd protein | / | 0.458 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.458 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.458 | |
| 3h2l | YAK | Genome polyprotein | 2.7.7.48 | 0.458 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.458 | |
| 4bs4 | A64 | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.458 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.458 | |
| 5kp2 | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 | / | 0.458 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.457 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.457 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4bux | F35 | Tankyrase-2 | 2.4.2.30 | 0.457 | |
| 4hx5 | 19V | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.456 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.456 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.456 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.456 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.456 | |
| 4hki | FLN | Tankyrase-2 | 2.4.2.30 | 0.456 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.456 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.455 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.455 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.455 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
| 3o8h | O8H | HTH-type transcriptional regulator EthR | / | 0.455 | |
| 3wag | TYD | Glycosyltransferase | / | 0.455 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4l34 | 1VG | Tankyrase-2 | 2.4.2.30 | 0.455 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.455 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.455 | |
| 4y0k | NAP | AntE | / | 0.455 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.455 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.454 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.454 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.454 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.454 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.454 | |
| 4e2y | JHZ | Methyltransferase | / | 0.454 | |
| 4e32 | DWN | Methyltransferase | / | 0.454 | |
| 4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.454 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 1g8j | MGD | Arsenite oxidase subunit AioA | 1.20.9.1 | 0.453 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.453 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.453 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4ggz | BTN | Bll1558 protein | / | 0.453 | |
| 4iue | AJ4 | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.452 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.452 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.452 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.452 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.452 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.452 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.452 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.452 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.452 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.452 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.452 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.451 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.451 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.451 | |
| 3n71 | SFG | Histone-lysine N-methyltransferase Smyd1 | / | 0.451 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.451 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.451 | |
| 4bui | W2E | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.451 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.451 | |
| 4l2x | YL2 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.451 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.451 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.451 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.450 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3frk | TQP | QdtB | / | 0.450 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.450 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.450 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.450 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.450 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.449 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.449 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.449 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.449 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.449 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.449 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.449 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.449 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.448 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.448 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.448 | |
| 3zg6 | APR | NAD-dependent protein deacetylase sirtuin-6 | 3.5.1 | 0.448 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.448 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.448 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.448 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.447 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 1gaw | FAD | Ferredoxin | / | 0.447 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.447 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.447 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.447 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.447 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.446 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.446 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.446 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2r8o | T5X | Transketolase 1 | / | 0.446 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.446 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 3br9 | DEY | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3kr8 | XAV | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.446 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.446 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.446 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.446 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.445 | |
| 1eio | GCH | Gastrotropin | / | 0.445 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.445 | |
| 1qsn | COA | HAT A1 | / | 0.445 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.445 | |
| 3lns | NAP | NAD(P)-dependent benzaldehyde dehydrogenase | 1.2.1.28 | 0.445 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.445 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.445 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.445 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4kxj | P34 | Nucleoprotein | / | 0.445 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.444 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.444 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3six | GDP | Nodulation protein Z | / | 0.444 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.444 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.444 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.444 | |
| 4zob | LGC | Lin1840 protein | / | 0.444 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.443 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.443 | |
| 2qzr | S79 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.443 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.443 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.443 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 4hlh | 20D | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4j22 | AJ7 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.443 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.443 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.442 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.442 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.442 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.442 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.442 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.442 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3igv | B80 | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.442 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 4hkk | AGI | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4hlg | 20B | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4kzu | A73 | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4mka | 2AY | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 4nv7 | COA | Arylamine N-acetyltransferase | / | 0.442 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.442 | |
| 4ldl | XQC | Beta-2 adrenergic receptor | / | 0.442 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.441 | |
| 1p3d | ANP | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.441 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1wkh | PPE | [LysW]-aminoadipate semialdehyde transaminase | / | 0.441 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.441 | |
| 3hml | PQQ | Pyrroloquinoline-quinone synthase | / | 0.441 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 3p0p | NNF | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 3qpv | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.441 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4hmh | F94 | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.441 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.441 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.440 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.440 | |
| 3f90 | FMN | Flavodoxin | / | 0.440 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.440 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.440 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.440 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.440 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.440 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.440 | |
| 4phl | PIL | Phosphodiesterase | / | 0.440 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.440 |