scPDB - Distribution of Binding site Similarity values of 4o2z entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4o2z	046	Mitogen-activated protein kinase

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4o2z	046	Mitogen-activated protein kinase	/	1.000
4c8b	0LI	Receptor-interacting serine/threonine-protein kinase 2	2.7.11.1	0.478
4agw	NG7	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.475
2oiq	STI	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.461
3dtw	A96	Vascular endothelial growth factor receptor 2	2.7.10.1	0.456
1iep	STI	Tyrosine-protein kinase ABL1	2.7.10.2	0.447
2hyy	STI	Tyrosine-protein kinase ABL1	2.7.10.2	0.443
3b8q	900	Vascular endothelial growth factor receptor 2	2.7.10.1	0.443
2qu6	857	Vascular endothelial growth factor receptor 2	2.7.10.1	0.440