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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4nkeRISFarnesyl pyrophosphate synthase2.5.1.10

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4nkeRISFarnesyl pyrophosphate synthase2.5.1.101.000
4q23RISFarnesyl pyrophosphate synthase2.5.1.100.528
1yv5RISFarnesyl pyrophosphate synthase2.5.1.100.503
3rbmB73Farnesyl pyrophosphate synthase, putative/0.497
3ldwZOLFarnesyl pyrophosphate synthase, putative/0.485
4lfvYS4Farnesyl pyrophosphate synthase2.5.1.100.481
2i191BYFarnesyl pyrophosphate synthase/0.476
1yq7RISFarnesyl pyrophosphate synthase2.5.1.100.444