Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4nbl | 2J6 | Caspase-6 | 3.4.22.59 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
4nbl | 2J6 | Caspase-6 | 3.4.22.59 | 1.000 | |
4nbn | 2J7 | Caspase-6 | 3.4.22.59 | 0.651 | |
1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.491 | |
1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
1thn | ADP | Anti-sigma F factor | / | 0.464 | |
2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.459 | |
1r8q | AFB | Cytohesin-2 | / | 0.457 | |
1r8q | AFB | ADP-ribosylation factor 1 | / | 0.457 | |
3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.457 | |
1klm | SPP | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
2cle | F6F | Tryptophan synthase alpha chain | / | 0.452 | |
1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.451 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.451 | |
1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.448 | |
4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.445 | |
2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.444 | |
3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.443 | |
3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.442 | |
4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.441 | |
3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.440 |