scPDB - Distribution of Binding site Similarity values of 4ms1 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4ms1	381	Gamma-aminobutyric acid type B receptor subunit 1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4ms1	381	Gamma-aminobutyric acid type B receptor subunit 1	/	1.000
4mr7	2BV	Gamma-aminobutyric acid type B receptor subunit 1	/	0.713
4mrm	2BY	Gamma-aminobutyric acid type B receptor subunit 1	/	0.682
4mr9	2BX	Gamma-aminobutyric acid type B receptor subunit 1	/	0.623
1obn	ASV	Isopenicillin N synthase	1.21.3.1	0.489
4kby	C2E	Stimulator of interferon genes protein	/	0.473
2rqf	JH3	Hemolymph juvenile hormone binding protein	/	0.468
1nlm	UD1	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	/	0.464
4e90	7RG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.464
1xva	SAM	Glycine N-methyltransferase	2.1.1.20	0.459
2qim	ZEA	Class 10 plant pathogenesis-related protein	/	0.459
4gv4	MEJ	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.459
2wzy	SQX	Soluble acetylcholine receptor	/	0.458
1nsg	RAD	Peptidyl-prolyl cis-trans isomerase FKBP1A	5.2.1.8	0.457
1nsg	RAD	Serine/threonine-protein kinase mTOR	2.7.11.1	0.457
4uym	VOR	14-alpha sterol demethylase Cyp51B	/	0.457
2fap	RAD	Peptidyl-prolyl cis-trans isomerase FKBP1A	5.2.1.8	0.456
2fap	RAD	Serine/threonine-protein kinase mTOR	2.7.11.1	0.456
3k3h	BYE	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.456
4b68	NAP	L-ornithine N(5)-monooxygenase	/	0.453
1h60	STR	Pentaerythritol tetranitrate reductase	/	0.452
2ylr	NAP	Phenylacetone monooxygenase	1.14.13.92	0.452
4gv0	8ME	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.452
3b8x	G4M	Putative pyridoxamine 5-phosphate-dependent dehydrase	/	0.451
3h3t	16H	Collagen type IV alpha-3-binding protein	/	0.451
5e5h	0T1	Succinyl-CoA:acetate CoA-transferase	/	0.451
1i5r	HYC	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.450
1o1t	2NH	Protein farnesyltransferase subunit beta	2.5.1.58	0.450
1ps9	MDE	2,4-dienoyl-CoA reductase	1.3.1.34	0.450
2po3	T4K	4-dehydrase	/	0.450
3u57	DH8	Raucaffricine-O-beta-D-glucosidase	3.2.1.125	0.450
4bca	FAD	Alkyldihydroxyacetonephosphate synthase, peroxisomal	2.5.1.26	0.450
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.450
4bfz	ZVZ	Pantothenate kinase	2.7.1.33	0.450
3h3q	H13	Collagen type IV alpha-3-binding protein	/	0.449
2lfo	GCH	Fatty acid-binding protein, liver	/	0.448
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.448
4x7z	ZM3	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.448
2g1y	5IG	Renin	3.4.23.15	0.447
2i65	NAD	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	3.2.2.6	0.447
2xuk	TZ5	Acetylcholinesterase	3.1.1.7	0.447
2zat	NAP	Dehydrogenase/reductase SDR family member 4	1.1.1.184	0.447
3dyq	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.447
3gjw	GJW	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.447
4xgu	ADP	Putative pachytene checkpoint protein 2	/	0.447
3bk2	U5P	Ribonuclease J	/	0.446
2b58	COA	Diamine acetyltransferase 1	/	0.445
3qt6	2P0	Mevalonate diphosphate decarboxylase	/	0.445
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.445
4fxy	0W2	Neurolysin, mitochondrial	3.4.24.16	0.445
4gh6	LUO	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.445
4q0k	GA3	Phytohormone-binding protein	/	0.445
2c9z	QUE	Anthocyanidin 3-O-glucosyltransferase 2	2.4.1.115	0.444
2cek	N8T	Acetylcholinesterase	3.1.1.7	0.444
2g27	4LG	Renin	3.4.23.15	0.444
2q1s	NAI	Putative nucleotide sugar epimerase/ dehydratase	/	0.444
2vpr	TDC	Tetracycline repressor protein class H	/	0.444
3e34	ED1	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	/	0.444
3e34	ED1	Protein farnesyltransferase subunit beta	2.5.1.58	0.444
3lqs	PSZ	D-alanine aminotransferase	2.6.1.21	0.444
4bft	ZVT	Pantothenate kinase	2.7.1.33	0.444
4x7v	MIV	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.444
1q0z	AKA	Aclacinomycin methylesterase RdmC	3.1.1.95	0.443
3fkt	SII	Beta-secretase 1	3.4.23.46	0.443
4a86	2AN	Major pollen allergen Bet v 1-A	/	0.443
3eu5	GBO	Protein farnesyltransferase subunit beta	2.5.1.58	0.442
3zm6	2GN	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	/	0.442
4a87	NAR	Major pollen allergen Bet v 1-A	/	0.442
4c13	UML	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase	/	0.442
4p9d	TMP	Deoxycytidylate deaminase	/	0.442
1rft	PXM	Pyridoxal kinase	2.7.1.35	0.441
3q43	D66	M1 family aminopeptidase	3.4.11	0.441
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.441
4dri	RAP	Serine/threonine-protein kinase mTOR	2.7.11.1	0.441
4dri	RAP	Peptidyl-prolyl cis-trans isomerase FKBP5	5.2.1.8	0.441
2g8y	NAD	Hydroxycarboxylate dehydrogenase B	/	0.440
2v16	C47	Renin	3.4.23.15	0.440
3c3e	GDP	2-phospho-L-lactate transferase	/	0.440
3dop	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.440
3g1r	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.440
3oag	LPQ	Renin	3.4.23.15	0.440
3zvm	ADP	Bifunctional polynucleotide phosphatase/kinase	2.7.1.78	0.440
4ey7	E20	Acetylcholinesterase	3.1.1.7	0.440