sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4mrx | CZH | Obelin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4mrx | CZH | Obelin | / | 1.000 | |
| 4n1f | CZH | Obelin | / | 0.693 | |
| 1qv0 | CZH | Obelin | / | 0.656 | |
| 1el4 | CTZ | Obelin | / | 0.633 | |
| 1qv1 | CZH | Obelin | / | 0.628 | |
| 1jf2 | CZH | Obelin | / | 0.626 | |
| 1jf0 | CZH | Obelin | / | 0.614 | |
| 1uhh | CZP | Aequorin-2 | / | 0.601 | |
| 1s36 | CEI | Obelin | / | 0.599 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.594 | |
| 1uhj | CZB | Aequorin-2 | / | 0.578 | |
| 4nqg | CZH | Mitrocomin | / | 0.566 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.548 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.511 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.506 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.506 | |
| 3hyw | DCQ | Sulfide-quinone reductase | / | 0.506 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.504 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.500 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.498 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.498 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.497 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.494 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.492 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.492 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.491 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.490 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.488 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.486 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.486 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.486 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.485 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.485 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.484 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.484 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.483 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.483 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.482 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.482 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.481 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.481 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.481 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.479 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.477 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.476 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.476 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.476 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.475 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.475 | |
| 3up3 | XCA | aceDAF-12 | / | 0.475 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.474 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.474 | |
| 3l71 | AZO | Cytochrome b | / | 0.474 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.472 | |
| 3n5x | XFK | Nitric oxide synthase, brain | 1.14.13.39 | 0.472 | |
| 3n65 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.472 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.471 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4kyk | IMN | Lactoylglutathione lyase | 4.4.1.5 | 0.471 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.471 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.470 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.470 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.470 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.470 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.470 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.469 | |
| 2vcg | S17 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.469 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.469 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.468 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.468 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.468 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.467 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.466 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.466 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 4iah | 1DX | Alr2278 protein | / | 0.466 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.465 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.465 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.465 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.464 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.463 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.463 | |
| 3htj | ET | EbrA repressor | / | 0.463 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.462 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.462 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.460 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.460 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.460 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.460 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.460 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.459 | |
| 2x9g | LYA | Pteridine reductase | / | 0.459 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3hth | PRL | EbrA repressor | / | 0.459 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.459 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 5cto | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.459 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.458 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.458 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.457 | |
| 2yhu | WHF | Pteridine reductase | / | 0.457 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.457 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.457 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.457 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.456 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.456 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.456 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 4cx5 | HW8 | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.454 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.454 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.454 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.454 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.454 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.453 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.453 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.453 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.453 | |
| 3n5w | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.453 | |
| 3p9t | TCL | Repressor | / | 0.453 | |
| 3t31 | DCQ | Sulfide-quinone reductase | / | 0.453 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.453 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.452 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.452 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2fq6 | P3F | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.451 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.451 | |
| 4nbi | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.451 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.450 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.450 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3fnu | 006 | HAP protein | / | 0.450 | |
| 3jq6 | DX1 | Pteridine reductase, putative | / | 0.450 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.450 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.450 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1pj7 | FFO | Dimethylglycine oxidase | 1.5.3.10 | 0.449 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.449 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2zoz | ET | Transcriptional regulator | / | 0.449 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3n62 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 3png | 8CX | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.449 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.449 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.449 | |
| 4boe | CLR | Japanin | / | 0.449 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.449 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2hzq | STR | Apolipoprotein D | / | 0.448 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.448 | |
| 3hx3 | RET | Retinaldehyde-binding protein 1 | / | 0.448 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3n66 | XFN | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 3roe | THM | NAD(P)H-hydrate epimerase | 5.1.99.6 | 0.448 | |
| 3tgu | WF3 | Cytochrome b | / | 0.448 | |
| 4gn6 | TYL | Lactoperoxidase | 1.11.1.7 | 0.448 | |
| 4iae | 1DX | Alr2278 protein | / | 0.448 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.448 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.447 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2yiu | SMA | Cytochrome b | / | 0.447 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.447 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.447 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.446 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.446 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.446 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
| 4dm8 | REA | Retinoic acid receptor beta | / | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.446 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1c7o | PPG | Hemolysin | / | 0.445 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.445 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1tfz | 869 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.445 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.445 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.445 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3n61 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.445 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.445 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.444 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.444 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4mm4 | 8PR | Na(+):neurotransmitter symporter (Snf family) | / | 0.444 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3hy4 | N5G | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.443 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.443 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.443 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 2vbv | FMN | Riboflavin kinase | 2.7.1.161 | 0.442 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.442 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3n60 | XFN | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.442 | |
| 3u3o | 3QV | Sulfotransferase 1A1 | 2.8.2.1 | 0.442 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.441 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.441 | |
| 2gqn | BLP | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.441 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.441 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.441 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3nlq | JRR | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3rqm | X2E | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.441 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.441 | |
| 3ufw | HW0 | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.441 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1ddt | APU | Diphtheria toxin | / | 0.440 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.440 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.440 | |
| 3bmn | AX3 | Pteridine reductase | / | 0.440 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 3rql | X2D | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4jsf | QJ4 | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 |