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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4mka2AYGenome polyprotein2.7.7.48

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4mka2AYGenome polyprotein2.7.7.481.000
4mkb28VGenome polyprotein2.7.7.480.791
4mk928RGenome polyprotein2.7.7.480.667
3u4r08FGenome polyprotein2.7.7.480.639
3igvB80Genome polyprotein2.7.7.480.634
3g86T18Genome polyprotein2.7.7.480.626
2giqNN2Genome polyprotein2.7.7.480.608
3tyvHI3Genome polyprotein2.7.7.480.606
3br9DEYGenome polyprotein2.7.7.480.602
3bsc2PDGenome polyprotein2.7.7.480.601
3hkwIX6Genome polyprotein2.7.7.480.600
3gynB42Genome polyprotein2.7.7.480.598
3hkyIX6Genome polyprotein2.7.7.480.591
3uph0C1Genome polyprotein2.7.7.480.570
3d5m4MSGenome polyprotein2.7.7.480.564
3h59H59Genome polyprotein2.7.7.480.564
3h2lYAKGenome polyprotein2.7.7.480.536
3u4o08EGenome polyprotein2.7.7.480.535
3csoXNIGenome polyprotein2.7.7.480.531
3d28B34Genome polyprotein2.7.7.480.509
3ska053Genome polyprotein2.7.7.480.509
3ske054Genome polyprotein2.7.7.480.488
4eaw0NQGenome polyprotein2.7.7.480.484
2yoj8Y6Genome polyprotein2.7.7.480.481
3gnvXNZGenome polyprotein2.7.7.480.481
2gc8885Polyprotein/0.477