scPDB - Distribution of Binding site Similarity values of 4man entry / Site 1

PDB ID	HET	Uniprot Name	EC Number
4man	1Y1	Apoptosis regulator Bcl-2

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4man	1Y1	Apoptosis regulator Bcl-2	/	1.000
4lxd	1XV	Apoptosis regulator Bcl-2	/	0.613
4lvt	1XJ	Apoptosis regulator Bcl-2	/	0.586
2o21	43B	Apoptosis regulator Bcl-2	/	0.519
4ktt	SAM	S-adenosylmethionine synthase isoform type-2	2.5.1.6	0.509
4ajw	VWN	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	2.7.1.153	0.500
4few	PP2	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.496
3ujl	A8S	Abscisic acid receptor PYL2	/	0.495
4hfn	CIY	2-alkenal reductase (NADP(+)-dependent)	/	0.494
4hni	16W	Casein kinase I isoform epsilon	2.7.11.1	0.492
1fp1	HCC	Isoliquiritigenin 2'-O-methyltransferase	/	0.490
4o76	1M3	Bromodomain-containing protein 4	/	0.490
1cjc	FAD	NADPH:adrenodoxin oxidoreductase, mitochondrial	1.18.1.6	0.485
2zce	PYL	Pyrrolysine--tRNA ligase	/	0.485
4jlj	1NM	Deoxycytidine kinase	2.7.1.74	0.485
4ndn	SAM	S-adenosylmethionine synthase isoform type-2	2.5.1.6	0.485
3uza	T4G	Adenosine receptor A2a	/	0.485
2b36	5PP	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.484
3cse	N22	Uncharacterized protein	/	0.484
4ddr	MMV	Dihydrofolate reductase	1.5.1.3	0.484
1xp9	AIJ	Estrogen receptor	/	0.483
1m9j	CLW	Nitric oxide synthase, endothelial	1.14.13.39	0.482
4bfr	J82	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	2.7.1.153	0.482
2chw	039	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.481
2e9a	B28	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.481
3gcu	R48	Mitogen-activated protein kinase 14	/	0.481
3w5e	NVW	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.481
1m9m	6NI	Nitric oxide synthase, endothelial	1.14.13.39	0.480
1dg5	TOP	Dihydrofolate reductase	1.5.1.3	0.479
1hnv	TBO	Gag-Pol polyprotein	2.7.7.49	0.479
2olc	ADP	Methylthioribose kinase	2.7.1.100	0.479
4ezk	0SD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.479
1e1n	FAD	NADPH:adrenodoxin oxidoreductase, mitochondrial	1.18.1.6	0.478
2tsc	CB3	Thymidylate synthase	/	0.478
3gxo	MQA	Mitomycin biosynthesis 6-O-methyltransferase	/	0.478
3lq2	TDP	Pyruvate dehydrogenase E1 component	1.2.4.1	0.478
3kdj	A8S	Abscisic acid receptor PYL1	/	0.477
3sh2	5DR	Dihydrofolate reductase	1.5.1.3	0.477
2cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.476
4dsc	A8S	Abscisic acid receptor PYL3	/	0.476
3irn	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.475
3njo	PYV	Abscisic acid receptor PYR1	/	0.475
3pre	3RE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.475
1e90	MYC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.474
1m8h	6NI	Nitric oxide synthase, inducible	1.14.13.39	0.474
3nef	PYV	Abscisic acid receptor PYL1	/	0.474
1fgi	SU1	Fibroblast growth factor receptor 1	/	0.473
3njo	P2M	Abscisic acid receptor PYR1	/	0.473
3nmh	PYV	Abscisic acid receptor PYL2	/	0.473
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.472
1jlc	FTC	Gag-Pol polyprotein	2.7.7.49	0.471
1m9k	7NI	Nitric oxide synthase, endothelial	1.14.13.39	0.471
4fjz	4FJ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.471
4h96	14Q	Dihydrofolate reductase	1.5.1.3	0.471
1sqn	NDR	Progesterone receptor	/	0.470
1xpc	AIT	Estrogen receptor	/	0.470
2apg	FAD	Flavin-dependent tryptophan halogenase PrnA	1.14.19.9	0.470
4lsj	LSJ	Glucocorticoid receptor	/	0.470
1nd5	2BF	Prostatic acid phosphatase	3.1.3.2	0.469
2dub	CO8	Enoyl-CoA hydratase, mitochondrial	4.2.1.17	0.469
3ml8	ML8	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.469
3nxv	D2F	Dihydrofolate reductase	1.5.1.3	0.469
1e7v	LY2	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.468
1fby	REA	Retinoic acid receptor RXR-alpha	/	0.468
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.468
1s6q	TPB	Gag-Pol polyprotein	2.7.7.49	0.468
2eau	CZA	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.468
4z35	ON9	Lysophosphatidic acid receptor 1	/	0.468
1lcb	DHF	Thymidylate synthase	/	0.467
1wc0	APC	Adenylate cyclase	/	0.467
3zvu	A8S	Abscisic acid receptor PYR1	/	0.467
1xh4	R69	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.466
2i0z	FAD	NAD(FAD)-utilizing dehydrogenases	/	0.466
4lj3	C2E	Cyclic di-GMP phosphodiesterase YahA	3.1.4	0.466
4mxe	ACO	N-acetyltransferase ESCO1	2.3.1	0.466
1e3v	DXC	Steroid Delta-isomerase	5.3.3.1	0.465
1t7t	DHT	Androgen receptor	/	0.465
2g5o	DRQ	Estrogen receptor	/	0.465
3c3e	FO1	2-phospho-L-lactate transferase	/	0.465
4a9m	P9M	Bromodomain-containing protein 2	/	0.465
4iw8	KN3	Estrogen receptor	/	0.465
4lg5	A1O	Abscisic acid receptor PYL2	/	0.465
4zhi	ADP	Kinesin-like protein KIF11	/	0.465
3qak	UKA	Adenosine receptor A2a	/	0.465
2c31	ADP	Oxalyl-CoA decarboxylase	4.1.1.8	0.464
2iut	AGS	DNA translocase FtsK	/	0.464
4hw3	19G	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.464
4o71	CPB	Bromodomain-containing protein 4	/	0.464
1xp1	AIH	Estrogen receptor	/	0.463
1yim	CM4	Estrogen receptor	/	0.463
2acl	REA	Retinoic acid receptor RXR-alpha	/	0.463
2y7j	B49	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	2.7.11.19	0.463
3ox3	4X4	Ribosyldihydronicotinamide dehydrogenase [quinone]	/	0.463
4ezj	0SC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.463
1rdt	L79	Retinoic acid receptor RXR-alpha	/	0.462
1tdu	CB3	Thymidylate synthase	/	0.462
2q7g	CCL	Pyrrolysine--tRNA ligase	/	0.462
2yhd	TES	Androgen receptor	/	0.462
2yke	YKE	Heat shock protein HSP 90-alpha	/	0.462
3a1l	2CC	Cytochrome P450	/	0.462
3r6p	A8S	Abscisic acid receptor PYL10	/	0.462
3zlo	X8U	Bcl-2-like protein 1	/	0.462
4a30	QMI	Glycylpeptide N-tetradecanoyltransferase	/	0.462
4at2	ASD	Possible succinate dehydrogenase	/	0.462
4o95	245	Cytokinin dehydrogenase 4	/	0.462
4qjc	IXE	Dihydrofolate reductase	1.5.1.3	0.462
1ie9	VDX	Vitamin D3 receptor	/	0.461
3kdi	A8S	Abscisic acid receptor PYL2	/	0.461
3zvv	XAZ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.461
4a9h	TVP	Bromodomain-containing protein 2	/	0.461
4l64	C2F	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase	2.1.1.14	0.461
1e6e	FAD	NADPH:adrenodoxin oxidoreductase, mitochondrial	1.18.1.6	0.460
1e8z	STU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.460
2chz	093	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.460
2w3v	TOP	Dihydrofolate reductase	/	0.460
3um5	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.460
4wzy	ATP	Maltokinase	2.7.1.175	0.460
1xls	REA	Retinoic acid receptor RXR-alpha	/	0.459
2pul	ACP	Methylthioribose kinase	2.7.1.100	0.459
2r0c	FAD	Putative FAD-monooxygenase	/	0.459
3nxo	D2B	Dihydrofolate reductase	1.5.1.3	0.459
3qls	55V	Dihydrofolate reductase	1.5.1.3	0.459
4f64	0S8	Fibroblast growth factor receptor 1	/	0.459
4flh	14K	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.459
4ixe	IXE	Dihydrofolate reductase	1.5.1.3	0.459
4wdb	2AM	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.459
4z07	PCG	cGMP-dependent protein kinase 1	2.7.11.12	0.459
1axw	MTX	Thymidylate synthase	/	0.458
1lcb	TMP	Thymidylate synthase	/	0.458
1rf9	DBR	Camphor 5-monooxygenase	1.14.15.1	0.458
1uhl	MEI	Retinoic acid receptor RXR-beta	/	0.458
3anm	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	1.1.1.267	0.458
3c3d	FO1	2-phospho-L-lactate transferase	/	0.458
3nmv	PYV	Abscisic acid receptor PYL2	/	0.458
3nxy	D2H	Dihydrofolate reductase	1.5.1.3	0.458
3oji	PYV	Abscisic acid receptor PYL3	/	0.458
3tqb	FOL	Dihydrofolate reductase	/	0.458
5bpf	ADP	D-alanine--D-alanine ligase	/	0.458
1qzf	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.457
1zy5	ANP	eIF-2-alpha kinase GCN2	/	0.457
2b1z	17M	Estrogen receptor	/	0.457
2on6	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.457
2vwp	NDP	Glucose 1-dehydrogenase	/	0.457
3e7i	B2	Nitric oxide synthase, inducible	1.14.13.39	0.457
3itz	P66	Mitogen-activated protein kinase 14	/	0.457
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.457
4fw0	5KJ	Nitric oxide synthase, brain	1.14.13.39	0.457
5cc9	DDF	Dihydrofolate reductase	1.5.1.3	0.457
1bq1	CB3	Thymidylate synthase	/	0.456
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.456
1lhv	NOG	Sex hormone-binding globulin	/	0.456
1t87	CAM	Camphor 5-monooxygenase	1.14.15.1	0.456
2opq	HBQ	Gag-Pol polyprotein	2.7.7.49	0.456
3p9t	TCL	Repressor	/	0.456
3sa2	7DR	Dihydrofolate reductase	/	0.456
3sqq	99Z	Cyclin-dependent kinase 2	2.7.11.22	0.456
4hnc	0UT	Mandelate racemase	/	0.456
4m2x	TMQ	Dihydrofolate reductase	1.5.1.3	0.456
4nc3	ERM	5-hydroxytryptamine receptor 2B	/	0.456
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.456
1oh0	EQU	Steroid Delta-isomerase	5.3.3.1	0.455
1phg	MYT	Camphor 5-monooxygenase	1.14.15.1	0.455
1q3h	ANP	Cystic fibrosis transmembrane conductance regulator	/	0.455
1wbs	LI2	Mitogen-activated protein kinase 14	/	0.455
2a5u	QYT	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.455
2bbq	PFG	Thymidylate synthase	/	0.455
2l98	STL	Troponin C, slow skeletal and cardiac muscles	/	0.455
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.455
3qtz	X42	Cyclin-dependent kinase 2	2.7.11.22	0.455
3u8h	BHP	Phospholipase A2, membrane associated	/	0.455
4bhw	01K	Histone acetyltransferase p300	/	0.455
4kak	06U	Dihydrofolate reductase	1.5.1.3	0.455
4o70	1QK	Bromodomain-containing protein 4	/	0.455
4xoi	GTP	Transforming protein RhoA	/	0.455
5h84	1VU	Histone acetyltransferase KAT2A	2.3.1.48	0.455
1ao8	MTX	Dihydrofolate reductase	1.5.1.3	0.454
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.454
1mc1	PCX	Carboxyethyl-arginine beta-lactam-synthase	6.3.3.4	0.454
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.454
1qpe	PP2	Tyrosine-protein kinase Lck	2.7.10.2	0.454
2oym	MNI	Endoglycoceramidase II	/	0.454
3emd	SFG	Methyltransferase	/	0.454
3gyt	DL4	Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily	/	0.454
3i0r	RT3	Gag-Pol polyprotein	2.7.7.49	0.454
3qfv	NM7	Serine/threonine-protein kinase MRCK beta	2.7.11.1	0.454
3wgw	T2B	Proliferating cell nuclear antigen	/	0.454
3zw3	ZW3	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.454
4f1s	F1S	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.454
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.454
4rbs	0RV	Metallo-beta-lactamase type 2	/	0.454
1g50	EST	Estrogen receptor	/	0.453
1g6c	IFP	Thiamine-phosphate synthase	/	0.453
1j3i	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.453
1jtu	LYB	Thymidylate synthase	/	0.453
1ni4	TPP	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	1.2.4.1	0.453
1ni4	TPP	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	1.2.4.1	0.453
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.453
1soj	IBM	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	3.1.4.17	0.453
2vkd	UPG	Cytotoxin L	/	0.453
2ze2	T27	Gag-Pol polyprotein	2.7.7.49	0.453
3dey	DHT	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.453
3hy4	N5G	5-formyltetrahydrofolate cyclo-ligase	6.3.3.2	0.453
3klm	DHT	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.453
3p99	LNP	Lanosterol 14-alpha-demethylase	/	0.453
3uvv	REA	Retinoic acid receptor RXR-alpha	/	0.453
4ds8	A8S	Abscisic acid receptor PYL3	/	0.453
4gkh	0J9	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.453
4hvb	19P	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.453
4iar	ERM	5-hydroxytryptamine receptor 1B	/	0.453
4jbt	ASD	Cytochrome P450 monooxygenase	/	0.453
4k7a	DHT	Androgen receptor	/	0.453
4oic	A8S	Bet v I allergen-like	/	0.453
1eet	BFU	Gag-Pol polyprotein	2.7.7.49	0.452
1vrq	FON	Subunit alpha of sarocosine oxidase	/	0.452
2cpp	CAM	Camphor 5-monooxygenase	1.14.15.1	0.452
2phk	ATP	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	2.7.11.19	0.452
3a8w	ATP	Protein kinase C iota type	2.7.11.13	0.452
3cs9	NIL	Tyrosine-protein kinase ABL1	2.7.10.2	0.452
3qj5	022	Alcohol dehydrogenase class-3	1.1.1.1	0.452
3r1s	X73	Cyclin-dependent kinase 2	2.7.11.22	0.452
4fk3	325	Serine/threonine-protein kinase B-raf	2.7.11.1	0.452
4uga	Q05	Nitric oxide synthase oxygenase	1.14.13.165	0.452
5h86	BCO	Histone acetyltransferase KAT2A	2.3.1.48	0.452
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.451
1siq	FAD	Glutaryl-CoA dehydrogenase, mitochondrial	1.3.8.6	0.451
2azz	TCH	Phospholipase A2, major isoenzyme	3.1.1.4	0.451
2ji9	ADP	Oxalyl-CoA decarboxylase	4.1.1.8	0.451
2q28	ADP	Oxalyl-CoA decarboxylase	4.1.1.8	0.451
2ykb	YKB	Heat shock protein HSP 90-alpha	/	0.451
3dmj	GWE	Pol protein	/	0.451
3ml9	ML9	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.451
3p5k	P5K	Mitogen-activated protein kinase 14	/	0.451
3qbw	ADP	Anhydro-N-acetylmuramic acid kinase	/	0.451
4g1z	0VP	Vitamin D3 receptor A	/	0.451
4ng4	ADP	Phosphoglycerate kinase	/	0.451
5ckw	ANP	Uncharacterized protein	/	0.451
1hk4	T44	Serum albumin	/	0.450
1m9t	INE	Nitric oxide synthase, inducible	1.14.13.39	0.450
1wc1	TAT	Adenylate cyclase	/	0.450
2oh4	GIG	Vascular endothelial growth factor receptor 2	2.7.10.1	0.450
3gbk	2PQ	Peroxisome proliferator-activated receptor gamma	/	0.450
3i64	DNA	2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase	/	0.450
3k47	D09	Dihydrofolate reductase	1.5.1.3	0.450
3nta	FAD	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	/	0.450
3o73	O73	Ribosyldihydronicotinamide dehydrogenase [quinone]	/	0.450
3pej	BC2	Endoplasmin homolog, putative	/	0.450
3uba	HC4	Lactoperoxidase	1.11.1.7	0.450
3zrb	ORC	Progesterone receptor	/	0.450
3zsh	469	Mitogen-activated protein kinase 14	/	0.450
4elb	34R	Dihydrofolate reductase	/	0.450
4fa6	0TA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.450
4k5r	FAD	Oxygenase	/	0.450
4kne	1CY	Dihydrofolate reductase	1.5.1.3	0.450
4oa9	ANP	Protein BRASSINOSTEROID INSENSITIVE 1	2.7.10.1	0.450
5bp9	SAH	Putative methyltransferase protein	/	0.450
1ci7	CB3	Thymidylate synthase	2.1.1.45	0.449
1daj	MOT	Dihydrofolate reductase	1.5.1.3	0.449
1ke6	LS2	Cyclin-dependent kinase 2	2.7.11.22	0.449
1rx5	DDF	Dihydrofolate reductase	1.5.1.3	0.449
1xp6	AIU	Estrogen receptor	/	0.449
2jkc	FAD	Flavin-dependent tryptophan halogenase PrnA	1.14.19.9	0.449
3e8e	G98	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.449
3jwc	EKB	Dihydrofolate reductase	/	0.449
3nxr	D2D	Dihydrofolate reductase	1.5.1.3	0.449
3pm1	ET	HTH-type transcriptional regulator QacR	/	0.449
3qlw	N22	Dihydrofolate reductase	1.5.1.3	0.449
3qn1	A8S	Abscisic acid receptor PYR1	/	0.449
3s2a	2NQ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.449
3zlm	ANP	Adenosine monophosphate-protein transferase NmFic	2.7.7.n1	0.449
4ixf	IXF	Dihydrofolate reductase	1.5.1.3	0.449
1e8w	QUE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.448
1e8x	ATP	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.448
1jtk	THU	Cytidine deaminase	3.5.4.5	0.448
1m9r	INE	Nitric oxide synthase, endothelial	1.14.13.39	0.448
1sm2	STU	Tyrosine-protein kinase ITK/TSK	2.7.10.2	0.448
1wc5	APC	Adenylate cyclase	/	0.448
2bl9	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.448
2oax	SNL	Mineralocorticoid receptor	/	0.448
2px2	SAH	Genome polyprotein	2.7.7.48	0.448
2wzb	ADP	Phosphoglycerate kinase 1	2.7.2.3	0.448
2ylo	TES	Androgen receptor	/	0.448
2zba	ZBA	Trichothecene 3-O-acetyltransferase	/	0.448
3fhx	PLP	Pyridoxal kinase	2.7.1.35	0.448
3kb3	A8S	Abscisic acid receptor PYL2	/	0.448
3neg	PYV	Abscisic acid receptor PYL1	/	0.448
3nhy	A7B	Ribosyldihydronicotinamide dehydrogenase [quinone]	/	0.448
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.448
3qlr	QLR	Dihydrofolate reductase	1.5.1.3	0.448
3tm0	ANP	Aminoglycoside 3'-phosphotransferase	2.7.1.95	0.448
4as7	6LX	Kinesin-like protein KIF11	/	0.448
4dk5	0KO	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.448
4fjy	FJY	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.448
4gb9	0WR	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.448
4gr9	372	Ribosyldihydronicotinamide dehydrogenase [quinone]	/	0.448
5ej9	TPP	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	/	0.448
1fdu	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.447
1tl3	H20	Gag-Pol polyprotein	2.7.7.49	0.447
1vj3	TAB	Dihydrofolate reductase	1.5.1.3	0.447
1w2c	ANP	Inositol-trisphosphate 3-kinase A	2.7.1.127	0.447
2b00	GCH	Phospholipase A2, major isoenzyme	3.1.1.4	0.447
2b51	UTP	RNA editing complex protein MP57	/	0.447
2p1u	4TN	Retinoic acid receptor RXR-alpha	/	0.447
2qkr	IXM	Cdc2-like CDK2/CDC28 like protein kinase	/	0.447
3c11	GDM	ATP-dependent molecular chaperone HSP82	/	0.447
3dpd	41A	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.447
3k90	A8S	Abscisic acid receptor PYR1	/	0.447
3kb0	A8S	Abscisic acid receptor PYL2	/	0.447
3q5k	D1U	Heat shock protein 83-1	/	0.447
3vi5	M4M	Hematopoietic prostaglandin D synthase	/	0.447
3vrw	YS5	Vitamin D3 receptor	/	0.447
3zra	ORB	Progesterone receptor	/	0.447
4app	N53	Serine/threonine-protein kinase PAK 4	2.7.11.1	0.447
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.447
4h95	06U	Dihydrofolate reductase	1.5.1.3	0.447
4iv2	1GR	Estrogen receptor	/	0.447
4jib	1L6	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.447
4k5e	1Q7	Nitric oxide synthase, brain	1.14.13.39	0.447
1fm6	9CR	Retinoic acid receptor RXR-alpha	/	0.446
1h2b	NAJ	NAD-dependent alcohol dehydrogenase	/	0.446
1mvc	BM6	Retinoic acid receptor RXR-alpha	/	0.446
1rek	B8L	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.446
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.446
1unl	RRC	Cyclin-dependent-like kinase 5	2.7.11.1	0.446
2bak	AQZ	Mitogen-activated protein kinase 14	/	0.446
2blc	CP7	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.446
3bgp	VX1	Serine/threonine-protein kinase pim-1	2.7.11.1	0.446
3fu9	KIB	Laccase-1	1.10.3.2	0.446
3nj0	PYV	Abscisic acid receptor PYL2	/	0.446
3nnu	EDB	Mitogen-activated protein kinase 14	/	0.446
3nr4	PYV	Abscisic acid receptor PYL2	/	0.446
3p6o	ETG	Camphor 5-monooxygenase	1.14.15.1	0.446
3sgv	2BJ	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.446
3td8	D2R	Dihydrofolate reductase	1.5.1.3	0.446
3wze	BAX	Vascular endothelial growth factor receptor 2	2.7.10.1	0.446
4a9y	AQZ	Mitogen-activated protein kinase 14	/	0.446
1dkf	BMS	Retinoic acid receptor alpha	/	0.445
1fvt	106	Cyclin-dependent kinase 2	2.7.11.22	0.445
1ia3	TQ5	Dihydrofolate reductase	1.5.1.3	0.445
1lhw	ESM	Sex hormone-binding globulin	/	0.445
1sd2	MTH	S-methyl-5'-thioadenosine phosphorylase	/	0.445
1v0o	INR	Cell division control protein 2 homolog	2.7.11.22	0.445
2hb7	O1C	Vitamin D3 receptor	/	0.445
2j7y	E3O	Estrogen receptor beta	/	0.445
2nv6	ZID	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.445
2pui	ADP	Methylthioribose kinase	2.7.1.100	0.445
2q3e	UPG	UDP-glucose 6-dehydrogenase	1.1.1.22	0.445
2uzt	SS3	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.445
2wpw	ACO	Orf14	/	0.445
2z4z	SC0	Geranylgeranyl pyrophosphate synthase	/	0.445
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.445
3k3k	A8S	Abscisic acid receptor PYR1	/	0.445
3kpz	ZNE	Vitamin D3 receptor	/	0.445
3rmw	UPG	Glycogenin-1	2.4.1.186	0.445
4anx	534	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.445
4awk	CI1	Polymerase acidic protein	/	0.445
4flp	JQ1	Bromodomain testis-specific protein	/	0.445
4g34	924	Eukaryotic translation initiation factor 2-alpha kinase 3	2.7.11.1	0.445
4itb	NDP	Succinate-semialdehyde dehydrogenase	/	0.445
4lga	A2O	Abscisic acid receptor PYL2	/	0.445
4q5j	ANP	Protein BRASSINOSTEROID INSENSITIVE 1	2.7.10.1	0.445
1d2s	DHT	Sex hormone-binding globulin	/	0.444
1fin	ATP	Cyclin-dependent kinase 2	2.7.11.22	0.444
1fwm	CB3	Thymidylate synthase	/	0.444
1pkd	UCN	Cyclin-dependent kinase 2	2.7.11.22	0.444
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.444
1sus	SAH	Caffeoyl-CoA O-methyltransferase	2.1.1.104	0.444
2bkz	SBC	Cyclin-dependent kinase 2	2.7.11.22	0.444
2cch	ATP	Cyclin-dependent kinase 2	2.7.11.22	0.444
2i0e	PDS	Protein kinase C beta type	2.7.11.13	0.444
2jc6	QPP	Calcium/calmodulin-dependent protein kinase type 1D	2.7.11.17	0.444
2ouz	C3D	Estrogen receptor	/	0.444
2xkd	T3M	Serine/threonine-protein kinase Nek2	2.7.11.1	0.444
3at4	CCK	Casein kinase II subunit alpha	2.7.11.1	0.444
3dyn	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.444
3lfc	Z86	Mitogen-activated protein kinase 14	/	0.444
3med	65B	Gag-Pol polyprotein	2.7.7.49	0.444
3nf8	CDQ	Gag-Pol polyprotein	/	0.444
3qfx	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.444
3ssn	MVI	Mycinamicin VI 2''-O-methyltransferase	/	0.444
3zok	NAD	3-dehydroquinate synthase, chloroplastic	4.2.3.4	0.444
4czt	CPS	CBL-interacting serine/threonine-protein kinase 23	2.7.11.1	0.444
4fvz	4KJ	Nitric oxide synthase, brain	1.14.13.39	0.444
4gn6	TYL	Lactoperoxidase	1.11.1.7	0.444
4mlp	2CX	Cryptochrome-2	/	0.444
4xe6	06U	Dihydrofolate reductase	1.5.1.3	0.444
5d7q	4I5	NAD-dependent protein deacetylase sirtuin-2	3.5.1	0.444
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.443
1kl2	FON	Serine hydroxymethyltransferase	/	0.443
1s9q	OHT	Estrogen-related receptor gamma	/	0.443
1wc4	APC	Adenylate cyclase	/	0.443
2gzl	2AA	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	4.6.1.12	0.443
2pix	DHT	Androgen receptor	/	0.443
3b2w	9NH	Tyrosine-protein kinase Lck	2.7.10.2	0.443
3bfa	9OD	Odorant binding protein ASP1	/	0.443
3dg8	RJ6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.443
3fnl	SHA	Lactoperoxidase	/	0.443
3g58	988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.443
3hf6	LX0	Tryptophan 5-hydroxylase 1	1.14.16.4	0.443
3iel	U5P	Ribonuclease TTHA0252	3.1	0.443
3lak	KR1	Gag-Pol polyprotein	2.7.7.49	0.443
3nhp	HGZ	Ribosyldihydronicotinamide dehydrogenase [quinone]	/	0.443
3nxt	D2E	Dihydrofolate reductase	1.5.1.3	0.443
3o56	ZG1	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.443
3r7e	X88	Cyclin-dependent kinase 2	2.7.11.22	0.443
3tnw	F18	Cyclin-dependent kinase 2	2.7.11.22	0.443
3v94	WYQ	Phosphodiesterase	/	0.443
4fad	0TB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.443
4fcd	0T6	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.443
4fu0	ADP	D-alanine--D-alanine ligase	/	0.443
4mxx	DB8	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.443
4u0k	744	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.443
1dz8	CAM	Camphor 5-monooxygenase	1.14.15.1	0.442
1p6j	DP9	Nitric oxide synthase, brain	1.14.13.39	0.442
1tl7	ONM	Adenylate cyclase type 2	/	0.442
1tl7	ONM	Adenylate cyclase type 5	/	0.442
1w78	PD8	Dihydrofolate synthase/folylpolyglutamate synthase	6.3.2.12	0.442
2aa7	1CA	Mineralocorticoid receptor	/	0.442
2ar8	FAD	Flavin-dependent tryptophan halogenase PrnA	1.14.19.9	0.442
2blb	CP7	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.442
2giu	FBR	Estrogen receptor beta	/	0.442
2iya	ZIO	Oleandomycin glycosyltransferase	/	0.442
2ouu	35G	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.442
2p2h	994	Vascular endothelial growth factor receptor 2	2.7.10.1	0.442
2y60	M8F	Isopenicillin N synthase	1.21.3.1	0.442
3dqr	JI2	Nitric oxide synthase, brain	1.14.13.39	0.442
3lan	KBT	Gag-Pol polyprotein	2.7.7.49	0.442
3ls8	AJZ	Phosphatidylinositol 3-kinase catalytic subunit type 3	2.7.1.137	0.442
3nmn	PYV	Abscisic acid receptor PYL1	/	0.442
3rk7	08Z	Cyclin-dependent kinase 2	2.7.11.22	0.442
3sa1	6DR	Dihydrofolate reductase	/	0.442
3um6	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.442
4amj	CVD	Beta-1 adrenergic receptor	/	0.442
4bva	T3	Ketimine reductase mu-crystallin	1.5.1.25	0.442
4ia7	BIV	Vitamin D3 receptor A	/	0.442
4ol0	GTP	GTP-binding nuclear protein Ran	/	0.442
4x2q	NAD	Retinal dehydrogenase 2	1.2.1.36	0.442
5h8t	RTL	Retinol-binding protein 1	/	0.442
1ezf	IN0	Squalene synthase	2.5.1.21	0.441
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.441
1j3k	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.441
1tvw	CB3	Thymidylate synthase	/	0.441
2gnf	Y27	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
2iw6	QQ2	Cyclin-dependent kinase 2	2.7.11.22	0.441
2iw9	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.441
2r0p	K2C	Putative FAD-monooxygenase	/	0.441
2vag	V25	Dual specificity protein kinase CLK1	2.7.12.1	0.441
2vbd	V10	Isopenicillin N synthase	1.21.3.1	0.441
2yvw	EPU	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.441
2zth	SAM	Catechol O-methyltransferase	2.1.1.6	0.441
3eon	341	Glutaryl-CoA dehydrogenase	/	0.441
3i53	SAH	2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase	/	0.441
3qly	55V	Uncharacterized protein	/	0.441
3r6x	X84	Cyclin-dependent kinase 2	2.7.11.22	0.441
3ufo	HW4	Nitric oxide synthase, brain	1.14.13.39	0.441
3up0	D7S	aceDAF-12	/	0.441
4a9e	3PF	Bromodomain-containing protein 2	/	0.441
4a9o	A9O	Bromodomain-containing protein 2	/	0.441
4bbg	V02	Kinesin-like protein KIF11	/	0.441
4e0u	0MV	Cyclic dipeptide N-prenyltransferase	/	0.441
4eb4	D16	Thymidylate synthase	2.1.1.45	0.441
4ez3	0S0	Cyclin-dependent kinase 2	2.7.11.22	0.441
4iaq	2GM	5-hydroxytryptamine receptor 1B	/	0.441
4ivy	1GT	Estrogen receptor	/	0.441
4kp6	1S1	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.441
1dna	CB3	Thymidylate synthase	/	0.440
1dxr	MST	Reaction center protein L chain	/	0.440
1f28	F89	Thymidylate synthase	2.1.1.45	0.440
1hvy	D16	Thymidylate synthase	2.1.1.45	0.440
1k74	9CR	Retinoic acid receptor RXR-alpha	/	0.440
1knu	YPA	Peroxisome proliferator-activated receptor gamma	/	0.440
1rp7	TZD	Pyruvate dehydrogenase E1 component	1.2.4.1	0.440
1uzw	CDH	Isopenicillin N synthase	1.21.3.1	0.440
1wbt	WBT	Mitogen-activated protein kinase 14	/	0.440
1x7r	GEN	Estrogen receptor	/	0.440
1xiu	REA	Retinoic acid receptor RXR	/	0.440
1zaf	789	Estrogen receptor beta	/	0.440
1zkl	IBM	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	3.1.4.53	0.440
2b8t	THM	Thymidine kinase	/	0.440
2m56	CAM	Camphor 5-monooxygenase	1.14.15.1	0.440
2ovm	AS0	Progesterone receptor	/	0.440
2p15	EZT	Estrogen receptor	/	0.440
2w71	L23	Biotin carboxylase	6.3.4.14	0.440
2zym	ACX	Periplasmic binding protein	/	0.440
3cd2	MTX	Dihydrofolate reductase	1.5.1.3	0.440
3dga	RJ1	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.440
3e01	PZ2	Gag-Pol polyprotein	2.7.7.49	0.440
3gc7	B45	Mitogen-activated protein kinase 14	/	0.440
3w1w	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.440
3zoz	ADP	Phosphoglycerate kinase 1	2.7.2.3	0.440
4b12	C23	Glycylpeptide N-tetradecanoyltransferase	/	0.440
4dhy	S41	Glucokinase	2.7.1.2	0.440
4h7z	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.440
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.440
4jlm	1NN	Deoxycytidine kinase	2.7.1.74	0.440
4la7	A1O	Abscisic acid receptor PYL2	/	0.440
4nm9	FAD	Bifunctional protein PutA	/	0.440