sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4m99 | ACO | UDP-N-acetylgalactosaminyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4m99 | ACO | UDP-N-acetylgalactosaminyltransferase | / | 1.000 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.471 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.467 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.467 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.466 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.452 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.443 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.442 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.442 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.441 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.440 |