Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4m0e | 1YL | Acetylcholinesterase | 3.1.1.7 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
4m0e | 1YL | Acetylcholinesterase | 3.1.1.7 | 1.000 | |
4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.621 | |
2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.548 | |
4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.541 | |
1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.536 | |
2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.536 | |
1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.534 | |
1lke | DOG | Bilin-binding protein | / | 0.528 | |
2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.524 | |
1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.523 | |
2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.523 | |
1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.521 | |
4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.513 | |
4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.513 | |
4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.513 | |
4s1i | PLP | Pyridoxal kinase, putative | / | 0.513 | |
2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.511 | |
2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.510 | |
4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.509 | |
1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.505 | |
1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.504 | |
4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.504 | |
1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.503 | |
2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.503 | |
1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.502 | |
1lnm | DTX | Bilin-binding protein | / | 0.502 | |
1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.499 | |
1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.498 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.497 | |
4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.497 | |
4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.494 | |
3vil | SA0 | Beta-glucosidase | / | 0.493 | |
1x1a | SAM | C-20 methyltransferase | / | 0.491 | |
1d3d | BZT | Prothrombin | 3.4.21.5 | 0.490 | |
3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.490 | |
1sqi | 869 | 4-hydroxyphenylpyruvate dioxygenase | / | 0.489 | |
1x1b | SAH | C-20 methyltransferase | / | 0.489 | |
3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.489 | |
4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.487 | |
4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.487 | |
2wea | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.486 | |
4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.486 | |
4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.486 | |
4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.486 | |
1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.485 | |
1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.483 | |
3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.483 | |
4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.483 | |
4kxj | P34 | Nucleoprotein | / | 0.483 | |
3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.481 | |
3pqb | VGP | Putative oxidoreductase | / | 0.481 | |
4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.481 | |
4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.481 | |
1z71 | L17 | Prothrombin | 3.4.21.5 | 0.480 | |
3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.480 | |
4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.480 | |
4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.480 | |
4ntj | AZJ | P2Y purinoceptor 12 | / | 0.480 | |
1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.479 | |
3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.479 | |
4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.479 | |
1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
3ske | 054 | Genome polyprotein | 2.7.7.48 | 0.478 | |
4gd9 | BTN | Streptavidin | / | 0.478 | |
4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.478 | |
4isz | GAV | tRNA-splicing ligase RtcB | 6.5.1 | 0.478 | |
1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.477 | |
1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.477 | |
2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.477 | |
1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.476 | |
3pka | Y02 | Methionine aminopeptidase 2 | / | 0.475 | |
4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.473 | |
2jgs | BTN | Avidin | / | 0.473 | |
3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.473 | |
3klb | FMN | Uncharacterized protein | / | 0.473 | |
4b4w | 9L9 | Bifunctional protein FolD | / | 0.473 | |
1rxj | BNI | Streptavidin | / | 0.472 | |
2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.472 | |
4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.472 | |
4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.472 | |
1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.471 | |
1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.471 | |
1zm4 | TAD | Exotoxin A | 2.4.2.36 | 0.471 | |
2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.471 | |
3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.471 | |
1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
3e4v | FMN | Uncharacterized protein | / | 0.470 | |
3fpk | FAD | Ferredoxin-NADP reductase | / | 0.470 | |
3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.470 | |
1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.469 | |
1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.469 | |
2zdv | 37U | Prothrombin | 3.4.21.5 | 0.469 | |
3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.469 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.469 | |
1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.468 | |
2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.468 | |
3ai0 | PNW | Beta-glucosidase | / | 0.468 | |
3dr7 | GPD | GDP-perosamine synthase | / | 0.468 | |
3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.468 | |
3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
3oqk | S52 | Renin | 3.4.23.15 | 0.468 | |
3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.468 | |
3voi | RCB | Glucanase | / | 0.468 | |
4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
4e47 | 0N6 | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.468 | |
4mlp | 2CX | Cryptochrome-2 | / | 0.468 | |
1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.467 | |
1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.467 | |
2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.467 | |
2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
3arv | SAU | Chitinase A | / | 0.467 | |
3e6e | DCS | Alanine racemase | / | 0.467 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.467 | |
3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.467 | |
1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.466 | |
2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.466 | |
2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.466 | |
3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.466 | |
3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.466 | |
4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.466 | |
4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.466 | |
1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
1x8l | OXR | Retinol dehydratase | / | 0.465 | |
2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.465 | |
3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.465 | |
4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.465 | |
1d6w | 00R | Prothrombin | 3.4.21.5 | 0.464 | |
1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.464 | |
2anm | CDO | Prothrombin | 3.4.21.5 | 0.464 | |
2wzw | FMN | Nitroreductase NfnB | / | 0.464 | |
2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.464 | |
2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.464 | |
3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.464 | |
4j7h | TRH | PCZA361.3 | / | 0.464 | |
4xba | 5GP | Aprataxin-like protein | 3 | 0.464 | |
1hqt | NAP | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.463 | |
1mfz | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.463 | |
1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
2get | COK | Pantothenate kinase | 2.7.1.33 | 0.463 | |
2zda | 32U | Prothrombin | 3.4.21.5 | 0.463 | |
4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
4k38 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.463 | |
4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.463 | |
3d4s | TIM | Beta-2 adrenergic receptor | / | 0.463 | |
1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.462 | |
1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.462 | |
2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
3c27 | DKK | Prothrombin | 3.4.21.5 | 0.462 | |
3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
3gx9 | TXD | Morphinone reductase | / | 0.462 | |
3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.462 | |
3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.462 | |
3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.461 | |
2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.461 | |
2zgx | 29U | Prothrombin | 3.4.21.5 | 0.461 | |
4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.461 | |
4o6f | SAH | N-lysine methyltransferase SMYD2 | / | 0.461 | |
4zu4 | 4TG | WxcM-like protein | / | 0.461 | |
1njj | ORX | Ornithine decarboxylase | / | 0.460 | |
2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
2ejz | SAH | Diphthine synthase | / | 0.460 | |
2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.460 | |
2wzy | SQX | Soluble acetylcholine receptor | / | 0.460 | |
3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.460 | |
4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.460 | |
4q36 | CO8 | Uncharacterized protein | / | 0.460 | |
2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.459 | |
2zhe | 13U | Prothrombin | 3.4.21.5 | 0.459 | |
3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.459 | |
3n71 | SFG | Histone-lysine N-methyltransferase Smyd1 | / | 0.459 | |
4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.458 | |
1m9h | NAD | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.458 | |
1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.458 | |
1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.458 | |
2cbq | TH2 | Neocarzinostatin | / | 0.458 | |
2g24 | 7IG | Renin | 3.4.23.15 | 0.458 | |
2ohj | FMN | Type A flavoprotein FprA | 1 | 0.458 | |
3b9o | FMN | Alkane monoxygenase | / | 0.458 | |
3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.458 | |
4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.458 | |
4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.458 | |
4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.458 | |
1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.457 | |
1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
3eq6 | BCO | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.457 | |
4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.457 | |
4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.457 | |
5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.457 | |
1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.456 | |
1bu5 | RBF | Flavodoxin | / | 0.456 | |
2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.456 | |
2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.456 | |
2z78 | H86 | Geranylgeranyl pyrophosphate synthase | / | 0.456 | |
2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.456 | |
3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.456 | |
3dr4 | G4M | GDP-perosamine synthase | / | 0.456 | |
3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.456 | |
4dkv | 0KW | Envelope glycoprotein gp160 | / | 0.456 | |
4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.456 | |
1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.455 | |
1zgv | 501 | Prothrombin | 3.4.21.5 | 0.455 | |
2ohh | FMN | Type A flavoprotein FprA | 1 | 0.455 | |
3hl0 | NAD | Maleylacetate reductase | / | 0.455 | |
3irh | DTP | HD domain protein | / | 0.455 | |
4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.455 | |
1gr1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.454 | |
1jf0 | CZH | Obelin | / | 0.454 | |
1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.454 | |
1zgi | 382 | Prothrombin | 3.4.21.5 | 0.454 | |
2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.454 | |
2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.454 | |
2ycw | CAU | Beta-1 adrenergic receptor | / | 0.454 | |
3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.454 | |
3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.454 | |
3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.454 | |
4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.454 | |
4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.454 | |
4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.454 | |
5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.454 | |
5dp2 | NAP | CurF | / | 0.454 | |
1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.453 | |
2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.453 | |
2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.453 | |
2r2m | I50 | Prothrombin | 3.4.21.5 | 0.453 | |
3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.453 | |
3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.453 | |
4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.453 | |
1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.452 | |
1t57 | FMN | Conserved protein | / | 0.452 | |
2b3d | FAD | Modulator of drug activity B | / | 0.452 | |
2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
3pke | Y10 | Methionine aminopeptidase 2 | / | 0.452 | |
4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
4e32 | DWN | Methyltransferase | / | 0.452 | |
4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
4j7g | TRH | PCZA361.3 | / | 0.452 | |
4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
5jqh | CAU | Beta-2 adrenergic receptor | / | 0.452 | |
1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.451 | |
2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.451 | |
3hdy | GDU | UDP-galactopyranose mutase | / | 0.451 | |
3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.451 | |
4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
4bfd | 8T3 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.451 | |
4n65 | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.451 | |
1d9i | 00P | Prothrombin | 3.4.21.5 | 0.450 | |
1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
1vfs | DCS | Alanine racemase | / | 0.450 | |
1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.450 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.450 | |
2z3u | CRR | Cytochrome P450 | / | 0.450 | |
3arp | DEQ | Chitinase A | / | 0.450 | |
3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.450 | |
3kmt | SAH | Histone H3K27 methylase | / | 0.450 | |
3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.450 | |
3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
3w5u | FAD | Ferredoxin | / | 0.450 | |
4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
4hcy | 0YN | Transketolase | / | 0.450 | |
4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.450 | |
4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.450 | |
5c3a | URM | Histo-blood group ABO system transferase | / | 0.450 | |
1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.449 | |
1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.449 | |
3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.449 | |
3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
4b4v | L34 | Bifunctional protein FolD | / | 0.449 | |
4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
4iei | ADP | Gene 2 protein | / | 0.449 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.449 | |
4tkg | 09L | Tankyrase-2 | 2.4.2.30 | 0.449 | |
4y0k | NAP | AntE | / | 0.449 | |
5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.449 | |
4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.449 | |
1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.448 | |
1z4u | PH9 | Polyprotein | / | 0.448 | |
2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.448 | |
2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.448 | |
3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.448 | |
3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.448 | |
4at0 | FAD | Possible succinate dehydrogenase | / | 0.448 | |
4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.448 | |
4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.448 | |
4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.448 | |
1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.447 | |
1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.447 | |
1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.447 | |
2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.447 | |
2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.447 | |
3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.447 | |
3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.447 | |
4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.447 | |
4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.447 | |
1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.446 | |
1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.446 | |
1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.446 | |
1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.446 | |
1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.446 | |
1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
1rsg | FAD | Polyamine oxidase FMS1 | / | 0.446 | |
1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
1x1d | SAH | C-20 methyltransferase | / | 0.446 | |
2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.446 | |
2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.446 | |
2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.446 | |
2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.446 | |
2v5u | FMN | Flavodoxin | / | 0.446 | |
2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.446 | |
3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.446 | |
4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.446 | |
4ise | 1FW | Glucokinase | 2.7.1.2 | 0.446 | |
4q7f | 3D1 | Uncharacterized protein | / | 0.446 | |
4qen | SAH | Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4 | 2.1.1.43 | 0.446 | |
4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.446 | |
5d5b | CAU | Beta-2 adrenergic receptor | / | 0.446 | |
4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.446 | |
1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.445 | |
1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.445 | |
2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.445 | |
2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
2pj4 | 414 | Carboxypeptidase B | / | 0.445 | |
2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
3bmq | AX5 | Pteridine reductase | / | 0.445 | |
3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.445 | |
4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
4lut | DCS | Alanine racemase | / | 0.445 | |
5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
2y04 | 68H | Beta-1 adrenergic receptor | / | 0.445 | |
2ycz | I32 | Beta-1 adrenergic receptor | / | 0.445 | |
4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.445 | |
1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.444 | |
1fml | RTL | Retinol dehydratase | / | 0.444 | |
1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.444 | |
2xnv | VU3 | Soluble acetylcholine receptor | / | 0.444 | |
2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
2yhu | WHF | Pteridine reductase | / | 0.444 | |
3c1k | T15 | Prothrombin | 3.4.21.5 | 0.444 | |
3c6n | 2S8 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.444 | |
3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.444 | |
4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.444 | |
4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.444 | |
4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
4i6g | FAD | Cryptochrome-2 | / | 0.444 | |
4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.444 | |
4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.444 | |
4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.444 | |
5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.444 | |
5cfl | C2E | Stimulator of interferon genes protein | / | 0.444 | |
1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
1ych | FMN | Nitric oxide reductase | 1 | 0.443 | |
2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.443 | |
2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.443 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.443 | |
2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.443 | |
2xvv | 9DN | Serum albumin | / | 0.443 | |
2zfq | 45U | Prothrombin | 3.4.21.5 | 0.443 | |
3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.443 | |
4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.443 | |
4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.443 | |
5ewk | P34 | Putative secreted protein | / | 0.443 | |
1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.442 | |
1zzr | DP9 | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.442 | |
2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
2qe2 | 452 | Polyprotein | / | 0.442 | |
2ywl | FAD | Thioredoxin reductase related protein | / | 0.442 | |
3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
3gus | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.442 | |
3sff | 0DI | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.442 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
4br3 | U85 | Choline kinase alpha | 2.7.1.32 | 0.442 | |
4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.442 | |
4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.442 | |
4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
4yfy | 0FX | VioF | / | 0.442 | |
5c1m | CLR | Mu-type opioid receptor | / | 0.442 | |
5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.442 | |
1jum | BER | HTH-type transcriptional regulator QacR | / | 0.441 | |
1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
1q3a | NGH | Stromelysin-2 | 3.4.24.22 | 0.441 | |
1sm4 | FAD | Ferredoxin--NADP reductase | / | 0.441 | |
1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.441 | |
1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.441 | |
1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.441 | |
2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.441 | |
2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
2lfo | GCH | Fatty acid-binding protein, liver | / | 0.441 | |
2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.441 | |
2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
2y02 | WHJ | Beta-1 adrenergic receptor | / | 0.441 | |
3ou2 | SAH | SAM-dependent methyltransferase | / | 0.441 | |
3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.441 | |
3wle | NAD | (R)-specific carbonyl reductase | / | 0.441 | |
3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.441 | |
4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.441 | |
4hmw | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.441 | |
4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.441 | |
4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.441 | |
4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.441 | |
5doz | NDP | JamJ | / | 0.441 | |
4lde | P0G | Beta-2 adrenergic receptor | / | 0.441 | |
1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.440 | |
2g1o | 2IG | Renin | 3.4.23.15 | 0.440 | |
2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.440 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
2x96 | RX3 | Angiotensin-converting enzyme | 3.4.15.1 | 0.440 | |
2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
2zw5 | COA | Bleomycin acetyltransferase | / | 0.440 | |
3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
4c4o | NAD | SADH | / | 0.440 | |
4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.440 | |
4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.440 | |
5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.440 | |
5d6l | CAU | Beta-2 adrenergic receptor | / | 0.440 |