Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4lv6 | GDP | GTPase KRas |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4lv6 | GDP | GTPase KRas | / | 1.000 | |
| 4tq9 | GDP | GTPase KRas | / | 0.684 | |
| 4luc | GDP | GTPase KRas | / | 0.673 | |
| 4l8g | GDP | GTPase KRas | / | 0.666 | |
| 4lpk | GDP | GTPase KRas | / | 0.664 | |
| 4q02 | GDP | GTPase KRas | / | 0.658 | |
| 4l9s | GDP | GTPase HRas | / | 0.656 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.648 | |
| 2ce2 | GDP | GTPase HRas | / | 0.647 | |
| 2rgg | GNP | GTPase HRas | / | 0.647 | |
| 4q03 | GDP | GTPase KRas | / | 0.647 | |
| 4epx | GDP | GTPase KRas | / | 0.641 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.638 | |
| 4obe | GDP | GTPase KRas | / | 0.636 | |
| 4wa7 | GDP | GTPase KRas | / | 0.633 | |
| 4epw | GDP | GTPase KRas | / | 0.619 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.616 | |
| 3lbn | GNP | GTPase HRas | / | 0.614 | |
| 4lrw | GDP | GTPase KRas | / | 0.614 | |
| 4ldj | GDP | GTPase KRas | / | 0.613 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.610 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.610 | |
| 4nyi | GNP | GTPase HRas | / | 0.610 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.609 | |
| 4ql3 | GDP | GTPase KRas | / | 0.607 | |
| 3rs0 | GNP | GTPase HRas | / | 0.606 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.602 | |
| 3rs4 | GNP | GTPase HRas | / | 0.602 | |
| 3tgp | GNP | GTPase HRas | / | 0.602 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.601 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.600 | |
| 4g0n | GNP | GTPase HRas | / | 0.597 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.595 | |
| 3rs7 | GNP | GTPase HRas | / | 0.595 | |
| 4dls | GNP | GTPase HRas | / | 0.595 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.594 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.593 | |
| 3i3s | GNP | GTPase HRas | / | 0.588 | |
| 3x1w | GDP | Ras-related protein Rap-1b | / | 0.586 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.585 | |
| 2rge | GNP | GTPase HRas | / | 0.584 | |
| 3k9l | GNP | GTPase HRas | / | 0.584 | |
| 4dsu | GDP | GTPase KRas | / | 0.583 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.582 | |
| 3v4f | GNP | GTPase HRas | / | 0.582 | |
| 4nyj | GNP | GTPase HRas | / | 0.582 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.581 | |
| 3lbh | GNP | GTPase HRas | / | 0.579 | |
| 4xvq | GNP | GTPase HRas | / | 0.579 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.577 | |
| 2rgc | GNP | GTPase HRas | / | 0.577 | |
| 4dlz | GNP | GTPase HRas | / | 0.577 | |
| 3lbi | GNP | GTPase HRas | / | 0.574 | |
| 4dlt | GNP | GTPase HRas | / | 0.574 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.574 | |
| 2rgb | GNP | GTPase HRas | / | 0.573 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.572 | |
| 3ddc | GNP | GTPase HRas | / | 0.571 | |
| 4dsn | GCP | GTPase KRas | / | 0.571 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.569 | |
| 4xvr | GNP | GTPase HRas | / | 0.568 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.566 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.565 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.565 | |
| 3rsl | GNP | GTPase HRas | / | 0.565 | |
| 4l9w | GNP | GTPase HRas | / | 0.565 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.564 | |
| 4dlx | GNP | GTPase HRas | / | 0.564 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.563 | |
| 2msc | GDP | MHC class I alpha chain | / | 0.562 | |
| 3oiu | GNP | GTPase HRas | / | 0.562 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.561 | |
| 4dlv | GNP | GTPase HRas | / | 0.561 | |
| 4dso | GSP | GTPase KRas | / | 0.561 | |
| 2cl6 | CAG | GTPase HRas | / | 0.560 | |
| 1lfd | GNP | GTPase HRas | / | 0.557 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.557 | |
| 3k8y | GNP | GTPase HRas | / | 0.556 | |
| 3oiv | GNP | GTPase HRas | / | 0.555 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.554 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.554 | |
| 4k81 | GTP | GTPase HRas | / | 0.553 | |
| 3l8y | GNP | GTPase HRas | / | 0.552 | |
| 4dlw | GNP | GTPase HRas | / | 0.552 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.551 | |
| 2c5l | GTP | GTPase HRas | / | 0.550 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.550 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.549 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.548 | |
| 3oiw | GNP | GTPase HRas | / | 0.546 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.546 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.545 | |
| 2bme | GNP | Ras-related protein Rab-4A | / | 0.543 | |
| 3kud | GDP | GTPase HRas | / | 0.542 | |
| 3rs5 | GNP | GTPase HRas | / | 0.542 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.541 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.540 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.539 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.539 | |
| 1d5c | GDP | GTPase (Rab6) | / | 0.538 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.538 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.538 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.537 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.535 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.535 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.534 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.530 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.528 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.528 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.527 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.525 | |
| 1g16 | GDP | Ras-related protein SEC4 | / | 0.524 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.524 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.520 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.517 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.516 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.516 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.515 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.514 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.514 | |
| 5di3 | GNP | ADP-ribosylation factor-like protein 3 | / | 0.514 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.513 | |
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.512 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.512 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.512 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.512 | |
| 4mit | GTP | Rho-related protein racC | / | 0.512 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.511 | |
| 5b2z | GNP | GTPase HRas | / | 0.511 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.509 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.509 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.509 | |
| 2q3f | GNP | Ras-related GTP-binding protein D | / | 0.508 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.506 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.506 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.505 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.505 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.504 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.503 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.503 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.502 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.502 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.502 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.502 | |
| 4itr | GDP | Cell division control protein 42 homolog | / | 0.502 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.500 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.500 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.500 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.499 | |
| 4y0v | GDP | ADP-ribosylation factor 1, putative | / | 0.499 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.498 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.495 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.494 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.493 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.493 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.493 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.493 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.492 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.491 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.489 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.489 | |
| 4cox | IMN | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.487 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.486 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.486 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.485 | |
| 4g01 | GDP | Ras-related protein RABF2b | / | 0.485 | |
| 3ews | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.483 | |
| 4ylg | GDP | ADP-ribosylation factor 1, putative | / | 0.483 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.482 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.482 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.481 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.481 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.481 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.481 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.481 | |
| 3ref | GDP | Rho family GTPase | / | 0.479 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.478 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.478 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.478 | |
| 2gvd | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.477 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.477 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.477 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.477 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.476 | |
| 1ii6 | ADP | Kinesin-like protein KIF11 | / | 0.475 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.475 | |
| 1g6o | ADP | Cag alpha | / | 0.473 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1v8k | ANP | Kinesin-like protein KIF2C | / | 0.473 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.473 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.473 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.473 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.473 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.472 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.471 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.471 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.470 | |
| 2mse | GNP | MHC class I alpha chain | / | 0.470 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.469 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.468 | |
| 3wyg | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.468 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.468 | |
| 1unh | IXM | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.466 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.466 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.466 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.465 | |
| 2l0x | GDP | GTP-binding protein Rheb | / | 0.465 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.465 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.465 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.464 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.464 | |
| 1cul | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.463 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.463 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3up3 | XCA | aceDAF-12 | / | 0.463 | |
| 4tld | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.463 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.462 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.462 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.462 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.462 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.462 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.462 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.461 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.461 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.460 | |
| 4ohx | ADP | Protein clpf-1 | / | 0.460 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.460 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.459 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.459 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.459 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.458 | |
| 2r9e | SDX | Citrate synthase | 2.3.3.16 | 0.458 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.458 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.458 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.458 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.457 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.457 | |
| 4goj | GNP | ADP-ribosylation factor-like protein 3 | / | 0.457 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.457 | |
| 1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.456 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.456 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.456 | |
| 3r7w | GNP | GTP-binding protein GTR2 | / | 0.456 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 4ehv | 0SJ | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.455 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3moh | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.455 | |
| 4crz | ACO | PanD regulatory factor | / | 0.455 | |
| 4fid | GDP | G protein alpha subunit, putative | / | 0.455 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.455 | |
| 1bcp | ATP | Pertussis toxin subunit 4 | / | 0.454 | |
| 1bcp | ATP | Pertussis toxin subunit 5 | / | 0.454 | |
| 3cin | NAD | Myo-inositol-1-phosphate synthase-related protein | / | 0.454 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.454 | |
| 4kq2 | U5P | Glycogen [starch] synthase isoform 2 | 2.4.1.11 | 0.454 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.453 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.453 | |
| 3kro | IPE | Geranyl diphosphate synthase large subunit | / | 0.453 | |
| 4iah | 1DX | Alr2278 protein | / | 0.453 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.452 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.452 | |
| 3kwn | 23Z | Cathepsin S | 3.4.22.27 | 0.452 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.452 | |
| 4f08 | 1RS | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 4wbn | GTP | Tubulin alpha-1B chain | / | 0.452 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.452 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.451 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.451 | |
| 2p2m | PRX | Acetyl-coenzyme A synthetase | / | 0.451 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.451 | |
| 5ifi | PRX | Acetyl-coenzyme A synthetase | / | 0.451 | |
| 5kbw | RBF | Riboflavin transporter RibU | / | 0.451 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.451 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.450 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.450 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.450 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.450 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.450 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.450 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4bix | ADP | Sensor histidine kinase CpxA | / | 0.450 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.449 | |
| 2iut | AGS | DNA translocase FtsK | / | 0.449 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.449 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.449 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.449 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.448 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.448 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 3r9x | GNP | GTPase Era | / | 0.448 | |
| 4l8u | 9AZ | Serum albumin | / | 0.448 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.448 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.447 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.447 | |
| 1you | PFD | Collagenase 3 | 3.4.24 | 0.447 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.447 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.447 | |
| 3w10 | RO9 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 3w2w | ATP | CRISPR system Cmr subunit Cmr2 | / | 0.447 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.446 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2gci | MRR | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.446 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.446 | |
| 3zdf | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 4b6l | 9ZP | Serine/threonine-protein kinase PLK3 | 2.7.11.21 | 0.446 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.446 | |
| 4hi0 | GDP | Urease accessory protein UreG | / | 0.446 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.446 | |
| 1dj3 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.445 | |
| 1e0j | ANP | DNA primase/helicase | 2.7.7 | 0.445 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.445 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1n08 | ADP | Riboflavin kinase | 2.7.1.26 | 0.445 | |
| 1sez | OMN | Protoporphyrinogen oxidase, mitochondrial | 1.3.3.4 | 0.445 | |
| 2dpx | GDP | GTP-binding protein RAD | / | 0.445 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.445 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.445 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.445 | |
| 3lm8 | VIB | Thiamine pyrophosphokinase | 2.7.6.2 | 0.445 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.445 | |
| 4ag5 | ADP | Type IV secretory pathway VirB4 components-like protein | / | 0.445 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.445 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.445 | |
| 4ys0 | ADP | Protein translocase subunit SecA | / | 0.445 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.444 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.444 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.444 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.444 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3b9l | AZZ | Serum albumin | / | 0.444 | |
| 3bxz | ADP | Protein translocase subunit SecA | / | 0.444 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.444 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4cjq | VXO | Integrase | / | 0.444 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.444 | |
| 5je4 | SAH | Methyl transferase | / | 0.444 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1qm5 | PLP | Maltodextrin phosphorylase | 2.4.1.1 | 0.443 | |
| 2woa | 576 | Macrophage metalloelastase | 3.4.24.65 | 0.443 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.443 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4zol | GTP | Tubulin alpha-1B chain | / | 0.443 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.442 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.442 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.442 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4lv5 | ADP | Rhoptry protein 5B | / | 0.442 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.442 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.442 | |
| 5jqg | GTP | Tubulin alpha-1B chain | / | 0.442 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.441 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.441 | |
| 1wdt | GTP | Elongation factor G (EF-G-2) | / | 0.441 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.441 | |
| 2h2j | SFG | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.441 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.441 | |
| 2wu2 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.441 | |
| 2wu2 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.441 | |
| 2y65 | ADP | Kinesin heavy chain | / | 0.441 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.441 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4jdc | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.441 | |
| 4tl9 | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.441 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.441 | |
| 1nja | DCM | Thymidylate synthase | / | 0.440 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1zdw | FLV | Prenyltransferase | / | 0.440 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.440 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3tlj | SAH | Uncharacterized protein | / | 0.440 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.440 | |
| 4phl | PIL | Phosphodiesterase | / | 0.440 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.440 | |
| 4u0k | 744 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4u7w | NDP | MxaA | / | 0.440 | |
| 5ark | UMP | Ribonuclease 4 | 3.1.27 | 0.440 |