scPDB - Distribution of Binding site Similarity values of 4lmn entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4lmn	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4lmn	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	1.000
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.485
1s9j	BBM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.468
4an9	2P7	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.467
3os3	3OS	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.464
3v04	V04	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.457
3v01	3V0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.456
2p55	MRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.451
4an2	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.450
4anb	YQY	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.442
3orn	3OR	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.440