sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4la7 | A1O | Abscisic acid receptor PYL2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 1.000 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.621 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.549 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.543 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.539 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.525 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.523 | |
| 4ds8 | A8S | Abscisic acid receptor PYL3 | / | 0.507 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.503 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.503 | |
| 4oic | A8S | Bet v I allergen-like | / | 0.498 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.497 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.493 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.491 | |
| 3kb3 | A8S | Abscisic acid receptor PYL2 | / | 0.486 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.482 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.481 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 3k3k | A8S | Abscisic acid receptor PYR1 | / | 0.466 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.465 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.465 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.463 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.463 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.461 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.458 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.457 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3n1s | 5GP | Purine nucleoside phosphoramidase | / | 0.448 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.445 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.445 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.445 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 3u9e | COA | Lmo1369 protein | / | 0.444 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.444 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.442 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3nmv | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.442 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.441 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.441 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 2cd8 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.440 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.440 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.440 |