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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.25

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.251.000
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.557
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.555
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.554
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.546
3gxlQIGTGF-beta receptor type-12.7.11.300.545
4qmpDKISerine/threonine-protein kinase 242.7.11.10.544
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.542
3l8p0CEAngiopoietin-1 receptor2.7.10.10.540
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.539
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.538
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.534
3hmm855TGF-beta receptor type-12.7.11.300.533
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.532
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.531
3gubGUBDeath-associated protein kinase 12.7.11.10.531
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.529
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.529
4bgg844Activin receptor type-12.7.11.300.529
4hvi19STyrosine-protein kinase JAK32.7.10.20.528
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.527
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.527
1bygSTUTyrosine-protein kinase CSK/0.525
4hvh19RTyrosine-protein kinase JAK32.7.10.20.524
1h1r6CPCyclin-dependent kinase 22.7.11.220.523
2pvnP63Casein kinase II subunit alpha2.7.11.10.523
3be9P04Casein kinase II subunit alpha2.7.11.10.523
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.521
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.521
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.519
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.519
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.518
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.518
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.518
4hvg19QTyrosine-protein kinase JAK32.7.10.20.517
4wsqKSAAP2-associated protein kinase 12.7.11.10.517
1xjdSTUProtein kinase C theta type2.7.11.130.516
2iw84SPCyclin-dependent kinase 22.7.11.220.516
3eb0DRKUncharacterized protein/0.515
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.514
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.514
4hge15VTyrosine-protein kinase JAK2/0.514
5drdATPAurora kinase A2.7.11.10.514
1di8DTQCyclin-dependent kinase 22.7.11.220.513
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.513
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.513
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.512
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.512
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.511
3rmf20ZCyclin-dependent kinase 22.7.11.220.511
3eljGS7Mitogen-activated protein kinase 82.7.11.240.510
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.510
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.510
2xa4AZ5Tyrosine-protein kinase JAK2/0.509
5dt3ATPAurora kinase A2.7.11.10.509
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.508
3r9dX6BCyclin-dependent kinase 22.7.11.220.508
2c6tDT5Cyclin-dependent kinase 22.7.11.220.507
4dymIYZActivin receptor type-12.7.11.300.507
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.506
4e4m0NHTyrosine-protein kinase JAK2/0.506
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.506
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.505
2j4z626Aurora kinase A2.7.11.10.505
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.505
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.504
4i22IREEpidermal growth factor receptor2.7.10.10.504
5dr2ATPAurora kinase A2.7.11.10.504
1aq1STUCyclin-dependent kinase 22.7.11.220.503
3k5uPFQAurora kinase A2.7.11.10.503
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.503
4jia1K3Tyrosine-protein kinase JAK2/0.503
1ol5ADPAurora kinase A2.7.11.10.502
2b7aIZATyrosine-protein kinase JAK2/0.502
2xneASHAurora kinase A2.7.11.10.502
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.502
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.502
3iok1P6Tyrosine-protein kinase JAK2/0.501
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.501
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.501
5e8wSTUTGF-beta receptor type-12.7.11.300.501
2pvhP19Casein kinase II subunit alpha2.7.11.10.500
3mtfA3FActivin receptor type-12.7.11.300.499
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.499
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.498
3zh8C58Protein kinase C iota type2.7.11.130.498
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.498
3a60STURibosomal protein S6 kinase beta-12.7.11.10.496
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.496
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.495
2dwbANPAurora kinase A2.7.11.10.494
2ebaFADPutative glutaryl-CoA dehydrogenase/0.494
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.494
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.493
2iw94SPCyclin-dependent kinase 22.7.11.220.493
4c62XWWTyrosine-protein kinase JAK2/0.493
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.492
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.492
1u4dDBQActivated CDC42 kinase 1/0.491
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.491
5dn3ATPAurora kinase A2.7.11.10.491
1h1s4SPCyclin-dependent kinase 22.7.11.220.490
1kkq471Peroxisome proliferator-activated receptor alpha/0.490
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.490
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.490
5e8xSTUTGF-beta receptor type-12.7.11.300.490
1vjy460TGF-beta receptor type-12.7.11.300.489
2eufLQQCyclin-dependent kinase 62.7.11.220.489
2wotZZGTGF-beta receptor type-12.7.11.300.489
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.489
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.489
4c58824Cyclin-G-associated kinase2.7.11.10.489
4lopSB4Mitogen-activated protein kinase 14/0.489
5e92ANPTGF-beta receptor type-22.7.11.300.489
1gih1PUCyclin-dependent kinase 22.7.11.220.488
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.488
1oi9N20Cyclin-dependent kinase 22.7.11.220.488
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.488
2h96893Mitogen-activated protein kinase 82.7.11.240.488
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.488
3t113T1Gag-Pol polyprotein3.4.23.160.488
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.488
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.487
4jqeANPCasein kinase II subunit alpha2.7.11.10.487
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.487
5dr9SKEAurora kinase A2.7.11.10.487
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.486
3nieANPMitogen-activated protein kinase/0.486
3oroAGSSerine/threonine protein kinase/0.486
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.486
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.485
3rk507ZCyclin-dependent kinase 22.7.11.220.485
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.484
1yvj4STTyrosine-protein kinase JAK32.7.10.20.484
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.484
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.483
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.483
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.483
3oom507Activin receptor type-12.7.11.300.483
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.482
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.482
4fv7E94Mitogen-activated protein kinase 12.7.11.240.482
4gk2L66Ephrin type-A receptor 32.7.10.10.482
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.482
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.482
5dnrATPAurora kinase A2.7.11.10.482
5e8ySTUTGF-beta receptor type-22.7.11.300.482
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.481
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.481
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.481
4gmy0X5Tyrosine-protein kinase JAK2/0.481
2gtk208Peroxisome proliferator-activated receptor gamma/0.480
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.480
2w06FRVCyclin-dependent kinase 22.7.11.220.480
3du8553Glycogen synthase kinase-3 beta2.7.11.260.480
4yuqKS1Calmodulin-like domain protein kinase/0.480
1bxoPP7Penicillopepsin-13.4.23.200.479
2bhhRYUCyclin-dependent kinase 22.7.11.220.479
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.479
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.479
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.479
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.479
3zewSTUEphrin type-B receptor 42.7.10.10.479
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.479
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.478
2xnbY8LCyclin-dependent kinase 22.7.11.220.478
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.478
3s1h56ZCyclin-dependent kinase 22.7.11.220.478
3sw418KCyclin-dependent kinase 22.7.11.220.478
3uli1N3Cyclin-dependent kinase 22.7.11.220.478
3uyt0CKCasein kinase I isoform delta2.7.11.10.478
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.478
4nifANPMitogen-activated protein kinase 12.7.11.240.478
1mq4ADPAurora kinase A2.7.11.10.477
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.477
3dogNNNCyclin-dependent kinase 22.7.11.220.477
3hx4ANPCalmodulin-domain protein kinase 1/0.477
3lfnA27Cyclin-dependent kinase 22.7.11.220.477
3qtxX43Cyclin-dependent kinase 22.7.11.220.477
3r9oZ71Cyclin-dependent kinase 22.7.11.220.477
3rni21ZCyclin-dependent kinase 22.7.11.220.477
3vs3VSETyrosine-protein kinase HCK2.7.10.20.477
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.477
4eor4SPCyclin-dependent kinase 22.7.11.220.477
4fkw62KCyclin-dependent kinase 22.7.11.220.477
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.477
1om1IQACasein kinase II subunit alpha2.7.11.10.476
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.476
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.476
3ggfGVDSerine/threonine-protein kinase 26/0.476
3gu83GUDeath-associated protein kinase 12.7.11.10.476
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.476
4eok4SPCyclin-dependent kinase 22.7.11.220.476
4fko20KCyclin-dependent kinase 22.7.11.220.476
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.476
4jbpYPHAurora kinase A2.7.11.10.476
4uymVOR14-alpha sterol demethylase Cyp51B/0.476
1oiuN76Cyclin-dependent kinase 22.7.11.220.475
1rw8580TGF-beta receptor type-12.7.11.300.475
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.475
3qu0X40Cyclin-dependent kinase 22.7.11.220.475
3w18N13Aurora kinase A2.7.11.10.475
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.475
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.475
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.474
4c4jX21Dual specificity protein kinase TTK2.7.12.10.474
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.473
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.473
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.473
2q5g1FAPeroxisome proliferator-activated receptor delta/0.473
2w05FRTCyclin-dependent kinase 22.7.11.220.473
2wecPP5Penicillopepsin-13.4.23.200.473
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.473
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.473
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.473
4bcoT6QCyclin-dependent kinase 22.7.11.220.473
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.473
4kbk1QGCasein kinase I isoform delta2.7.11.10.473
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.473
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.473
1oirHDYCyclin-dependent kinase 22.7.11.220.472
1zeoC01Peroxisome proliferator-activated receptor gamma/0.472
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.472
4bgh3I6Cyclin-dependent kinase 22.7.11.220.472
4ez50RSCyclin-dependent kinase 62.7.11.220.472
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.472
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.472
4j5j478Gag-Pol polyprotein3.4.23.160.472
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.471
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.471
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.471
1ppm0P1Penicillopepsin-13.4.23.200.471
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
1xddAAYIntegrin alpha-L/0.471
2xyeCXGGag-Pol polyprotein/0.471
2zdt46CMitogen-activated protein kinase 102.7.11.240.471
2znnS44Peroxisome proliferator-activated receptor alpha/0.471
3le62BZCyclin-dependent kinase 22.7.11.220.471
3qtzX42Cyclin-dependent kinase 22.7.11.220.471
3ttjJBIMitogen-activated protein kinase 102.7.11.240.471
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.471
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.471
4jbqVX6Aurora kinase A2.7.11.10.471
4ux9ANPMitogen-activated protein kinase 82.7.11.240.471
1gii1PUCyclin-dependent kinase 22.7.11.220.470
1k6cMK1Gag-Pol polyprotein3.4.23.160.470
1oiyN41Cyclin-dependent kinase 22.7.11.220.470
1pmn984Mitogen-activated protein kinase 102.7.11.240.470
3rk708ZCyclin-dependent kinase 22.7.11.220.470
3so9017Pol protein/0.470
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.470
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.470
4gub0Y4Casein kinase II subunit alpha2.7.11.10.470
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.470
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.469
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.469
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.469
3w2sW2REpidermal growth factor receptor2.7.10.10.469
4b7xNAPProbable oxidoreductase/0.469
4ivc1J6Tyrosine-protein kinase JAK1/0.469
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.469
1ke6LS2Cyclin-dependent kinase 22.7.11.220.468
2om9AJAPeroxisome proliferator-activated receptor gamma/0.468
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.468
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.468
4anmWULCasein kinase II subunit alpha2.7.11.10.468
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.468
4dgnLU2Casein kinase II subunit alpha2.7.11.10.468
4loqSB4Mitogen-activated protein kinase 14/0.468
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.468
1e9hINRCyclin-dependent kinase 22.7.11.220.467
1k6pXN3Gag-Pol polyprotein3.4.23.160.467
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.467
3w33W19Epidermal growth factor receptor2.7.10.10.467
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
4f650S9Fibroblast growth factor receptor 1/0.467
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.467
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.467
4kba1QMCasein kinase I isoform delta2.7.11.10.467
4utdACPAurora kinase A2.7.11.10.467
1hiiC20Gag-Pol polyprotein/0.466
1oguST8Cyclin-dependent kinase 22.7.11.220.466
1xe65FPPlasmepsin-23.4.23.390.466
2i0ePDSProtein kinase C beta type2.7.11.130.466
2r3jSCJCyclin-dependent kinase 22.7.11.220.466
2uxpCLMHTH-type transcriptional regulator TtgR/0.466
3t3c017Gag-Pol polyprotein3.4.23.160.466
3t8oATPRhodopsin kinase/0.466
3zep1NXTyrosine-protein kinase JAK32.7.10.20.466
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.466
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.466
4ocvANPAminoglycoside phosphotransferase/0.466
2b52D42Cyclin-dependent kinase 22.7.11.220.465
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.465
2zb3NDPProstaglandin reductase 21.3.1.480.465
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.465
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.465
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.465
3slz3TLPutative gag-pro-pol polyprotein/0.465
4hjoAQ4Epidermal growth factor receptor2.7.10.10.465
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.465
1ol7ADPAurora kinase A2.7.11.10.464
1xkkFMMEpidermal growth factor receptor2.7.10.10.464
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.464
2excJNKMitogen-activated protein kinase 102.7.11.240.464
2hcdBIVVitamin D3 receptor A/0.464
2x1nX1NCyclin-dependent kinase 22.7.11.220.464
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.464
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.464
4aotGW8Serine/threonine-protein kinase 102.7.11.10.464
4cegADPAurora kinase A2.7.11.10.464
4jboWPHAurora kinase A2.7.11.10.464
4o0wADNAurora kinase A2.7.11.10.464
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.463
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.463
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.463
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.463
2qo9ANPEphrin type-A receptor 32.7.10.10.463
2xikJ60Serine/threonine-protein kinase 252.7.11.10.463
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.463
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.463
3ekp478Gag-Pol polyprotein3.4.23.160.463
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.463
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.463
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.463
3rak03ZCyclin-dependent kinase 22.7.11.220.463
3slkNDPPolyketide synthase extender module 2/0.463
4yryFADGlutamate synthase, beta subunit/0.463
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1pkdUCNCyclin-dependent kinase 22.7.11.220.462
1pxpCK8Cyclin-dependent kinase 22.7.11.220.462
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.462
1rkxNADCDP-D-glucose-4,6-dehydratase/0.462
1u54ACPActivated CDC42 kinase 1/0.462
1xe55FEPlasmepsin-23.4.23.390.462
1zys199Serine/threonine-protein kinase Chk12.7.11.10.462
2of2547Tyrosine-protein kinase Lck2.7.10.20.462
2vwx7X4Ephrin type-B receptor 42.7.10.10.462
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.462
3nxe2NCProtease/0.462
4qgiROCGag-Pol polyprotein3.4.23.160.462
5dpvSKEAurora kinase A2.7.11.10.462
1dirNADDihydropteridine reductase1.5.1.340.461
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1p9wANPType II secretion system protein E/0.461
1pjcNADAlanine dehydrogenase/0.461
2c5nCK8Cyclin-dependent kinase 22.7.11.220.461
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.461
2hog710Serine/threonine-protein kinase Chk12.7.11.10.461
2vu3LZECyclin-dependent kinase 22.7.11.220.461
2znq401Peroxisome proliferator-activated receptor delta/0.461
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.461
3rkb12ZCyclin-dependent kinase 22.7.11.220.461
3zuyTCHTransporter/0.461
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.461
4eon1ROCyclin-dependent kinase 22.7.11.220.461
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.461
4ia3BIVVitamin D3 receptor A/0.461
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.461
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.461
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.460
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.460
1pxlCK4Cyclin-dependent kinase 22.7.11.220.460
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.460
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.460
2izrBRKCasein kinase I isoform gamma-32.7.11.10.460
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.460
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
3pqbVGPPutative oxidoreductase/0.460
3r7kFDAProbable acyl CoA dehydrogenase/0.460
3rpv26ZCyclin-dependent kinase 22.7.11.220.460
3s56ROCProtease/0.460
3zmmF9JTyrosine-protein kinase JAK2/0.460
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.460
4gk3L87Ephrin type-A receptor 32.7.10.10.460
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.460
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4jajXU1Aurora kinase A2.7.11.10.460
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.460
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.459
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.459
3ekv478Gag-Pol polyprotein3.4.23.160.459
3gw9VNILanosterol 14-alpha-demethylase/0.459
3wmxNADNAD dependent epimerase/dehydratase/0.459
4b0gVEKAurora kinase A2.7.11.10.459
4erwSTUCyclin-dependent kinase 22.7.11.220.459
4jr7GNPCasein kinase II subunit alpha2.7.11.10.459
4xguADPPutative pachytene checkpoint protein 2/0.459
5a3bAPRSIR2 family protein/0.459
5jscFADPutative acyl-CoA dehydrogenase/0.459
1bxqPP8Penicillopepsin-13.4.23.200.458
1e1lFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.458
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1m2pHNACasein kinase II subunit alpha2.7.11.10.458
1sh9RITGag-Pol polyprotein3.4.23.160.458
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.458
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.458
2q59240Peroxisome proliferator-activated receptor gamma/0.458
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.458
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.458
3nbvANPKetohexokinase/0.458
3pe6ZYHMonoglyceride lipase/0.458
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4dplNAPMalonyl-CoA reductase1.2.1.750.458
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.458
4g3jVNTLanosterol 14-alpha-demethylase/0.458
4hnf16WCasein kinase I isoform delta2.7.11.10.458
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.458
4kb81QNCasein kinase I isoform delta2.7.11.10.458
4oauADP2-5A-dependent ribonuclease3.1.260.458
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1e1xNW1Cyclin-dependent kinase 22.7.11.220.457
1xl5190Gag-Pol polyprotein3.4.23.160.457
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.457
2pvlP55Casein kinase II subunit alpha2.7.11.10.457
2uxoTACHTH-type transcriptional regulator TtgR/0.457
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.457
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.457
3c4zADPRhodopsin kinase/0.457
3poz03PEpidermal growth factor receptor2.7.10.10.457
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.457
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.457
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4jq8KJ8Epidermal growth factor receptor2.7.10.10.457
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.457
1tj0FADBifunctional protein PutA1.5.5.20.456
2i40BLZCyclin-dependent kinase 22.7.11.220.456
2r3lSCWCyclin-dependent kinase 22.7.11.220.456
2uzlC94Cyclin-dependent kinase 22.7.11.220.456
2xngA0HAurora kinase A2.7.11.10.456
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.456
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.456
3eyhIZATyrosine-protein kinase JAK1/0.456
3h0aD30Peroxisome proliferator-activated receptor gamma/0.456
3kfr3TLGag-Pol polyprotein/0.456
3l6jZ90Alr2278 protein/0.456
3lzu017Gag-Pol polyprotein3.4.23.160.456
3q92XNBKetohexokinase/0.456
3sw719KCyclin-dependent kinase 22.7.11.220.456
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.456
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.456
3zuxTCHTransporter/0.456
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
4fob0USALK tyrosine kinase receptor2.7.10.10.456
4nr42LKCREB-binding protein/0.456
4wkqIREEpidermal growth factor receptor2.7.10.10.456
5dt4ATPAurora kinase A2.7.11.10.456
1bwsNDPGDP-L-fucose synthase/0.455
1hdrNADDihydropteridine reductase1.5.1.340.455
1jpaANPEphrin type-B receptor 22.7.10.10.455
1m2rMNYCasein kinase II subunit alpha2.7.11.10.455
1me6IVSPlasmepsin-23.4.23.390.455
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.455
1rl8RITGag-Pol polyprotein3.4.23.160.455
1urwI1PCyclin-dependent kinase 22.7.11.220.455
1vikBAYGag-Pol polyprotein/0.455
1yb5NAPQuinone oxidoreductase1.6.5.50.455
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.455
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.455
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.455
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.455
2ym2FADPhenylacetone monooxygenase1.14.13.920.455
3a62STURibosomal protein S6 kinase beta-12.7.11.10.455
3a9wNADNDP-sugar epimerase/0.455
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.455
4c61LMMTyrosine-protein kinase JAK2/0.455
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.455
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.455
4riyADPEpidermal growth factor receptor2.7.10.10.455
5aaaVGHALK tyrosine kinase receptor2.7.10.10.455
1meuDMPGag-Pol polyprotein3.4.23.160.454
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.454
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.454
2hw1ANPKetohexokinase/0.454
2p4yC03Peroxisome proliferator-activated receptor gamma/0.454
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.454
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.454
2x9fX9FEphrin type-B receptor 42.7.10.10.454
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.454
3own3OWRenin3.4.23.150.454
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.454
4a8v2ANMajor pollen allergen Bet v 1-J/0.454
4dgmAGICasein kinase II subunit alpha2.7.11.10.454
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.454
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.454
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.454
4lrjANPUncharacterized protein/0.454
4nk92K5Fibroblast growth factor receptor 1/0.454
4o0uADNAurora kinase A2.7.11.10.454
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1dawANPCasein kinase II subunit alpha2.7.11.10.453
1odyLP1Gag-Pol polyprotein3.4.23.160.453
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.453
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.453
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.453
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.453
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.453
2v7a627Tyrosine-protein kinase ABL12.7.10.20.453
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.453
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.453
2yac937Serine/threonine-protein kinase PLK12.7.11.210.453
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.453
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3ekwDR7Gag-Pol polyprotein3.4.23.160.453
3el4ROCGag-Pol polyprotein3.4.23.160.453
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.453
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.453
3r83Z14Cyclin-dependent kinase 22.7.11.220.453
4deeADPAurora kinase A2.7.11.10.453
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.453
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.453
4gk4L90Ephrin type-A receptor 32.7.10.10.453
4ylfFADDihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog/0.453
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.452
3icrCOACoenzyme A disulfide reductase/0.452
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.452
3sufSUEPolyprotein/0.452
3zpsEQMGag-Pol polyprotein3.4.23.160.452
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4dgo0JWCasein kinase II subunit alpha2.7.11.10.452
4ewhT77Activated CDC42 kinase 1/0.452
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.452
4qi5FADCellobiose dehydrogenase/0.452
4u0mGTPCyclic GMP-AMP synthase/0.452
4ye3G04Gag-Pol polyprotein3.4.23.160.452
3pwhZMAAdenosine receptor A2a/0.452
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.451
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.451
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.451
1rfuADPPyridoxal kinase2.7.1.350.451
1u28NADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.451
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.451
2np8CC3Aurora kinase A2.7.11.10.451
2p33J07Mitogen-activated protein kinase 102.7.11.240.451
2vx07X7Ephrin type-B receptor 42.7.10.10.451
2yfxVGHALK tyrosine kinase receptor2.7.10.10.451
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.451
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.451
3d7kD7KBenzaldehyde lyase/0.451
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.451
3sdkP3NProteasome subunit beta type-53.4.25.10.451
3sdkP3NProteasome subunit beta type-63.4.25.10.451
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.451
4dpmCOAMalonyl-CoA reductase1.2.1.750.451
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.451
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.451
5dt0SKEAurora kinase A2.7.11.10.451
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.450
1pjkANPCasein kinase II subunit alpha2.7.11.10.450
1py5PY1TGF-beta receptor type-12.7.11.300.450
2cciATPCyclin-dependent kinase 22.7.11.220.450
2of4979Tyrosine-protein kinase Lck2.7.10.20.450
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.450
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.450
3t2zFADSulfide-quinone reductase/0.450
3tneRITCandidapepsin-13.4.23.240.450
3ttp017Gag-Pol polyprotein3.4.23.160.450
4c4h7RODual specificity protein kinase TTK2.7.12.10.450
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.450
4ia2BIVVitamin D3 receptor A/0.450
4ivb1J5Tyrosine-protein kinase JAK1/0.450
4ruoBIVVitamin D3 receptor A/0.450
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
1idb0DOGag-Pol polyprotein/0.449
1m2qMNXCasein kinase II subunit alpha2.7.11.10.449
1sguMK1Gag-Pol polyprotein3.4.23.160.449
2ejvNADL-threonine 3-dehydrogenase/0.449
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.449
2itqITQEpidermal growth factor receptor2.7.10.10.449
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.449
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.449
2p3c3TLProtease/0.449
2pmlANPUncharacterized protein/0.449
2po7CHDFerrochelatase, mitochondrial4.99.1.10.449
2w17I19Cyclin-dependent kinase 22.7.11.220.449
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.449
2xp2VGHALK tyrosine kinase receptor2.7.10.10.449
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.449
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.449
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.449
3oy4017Gag-Pol polyprotein3.4.23.160.449
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.449
3sacAF8Protease/0.449
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.449
4fwjFADLysine-specific histone demethylase 1B10.449
4fz60VGTyrosine-protein kinase SYK2.7.10.20.449
4jpe1M7Beta-secretase 13.4.23.460.449
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.449
4ubsDIFPentalenic acid synthase1.14.15.110.449
5dp2NAPCurF/0.449
5hs1VORLanosterol 14-alpha demethylase/0.449
1e3eNAIAlcohol dehydrogenase 41.1.1.10.448
1i3mUD1UDP-glucose 4-epimerase/0.448
1ke7LS3Cyclin-dependent kinase 22.7.11.220.448
1lp4ANPCasein kinase II subunit alpha2.7.11.10.448
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.448
1w0xOLOCyclin-dependent kinase 22.7.11.220.448
2pym1UNGag-Pol polyprotein3.4.23.160.448
2znoS44Peroxisome proliferator-activated receptor gamma/0.448
3cgfJNFMitogen-activated protein kinase 102.7.11.240.448
3dcrKVSProtease/0.448
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.448
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.448
3s1dZIRCytokinin dehydrogenase 11.5.99.120.448
4j55031Gag-Pol polyprotein3.4.23.160.448
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.448
4lfiGNPCasein kinase II subunit alpha2.7.11.10.448
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.448
4q73FADBifunctional protein PutA/0.448
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1p4fDRGDeath-associated protein kinase 12.7.11.10.447
1xl2189Gag-Pol polyprotein3.4.23.160.447
2bfyH1NAurora kinase B-A2.7.11.10.447
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.447
2qdxFADFerredoxin--NADP+ reductase/0.447
2vttLZDCyclin-dependent kinase 22.7.11.220.447
2vv9IM9Cyclin-dependent kinase 22.7.11.220.447
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.447
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.447
3i59N6SCRP-like cAMP-activated global transcriptional regulator/0.447
3r8vZ62Cyclin-dependent kinase 22.7.11.220.447
3t14FADSulfide-quinone reductase/0.447
3uzp0CKCasein kinase I isoform delta2.7.11.10.447
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.447
4fkr45KCyclin-dependent kinase 22.7.11.220.447
4i8zG08Gag-Pol polyprotein3.4.23.160.447
4iah1DXAlr2278 protein/0.447
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
4r21STRCytochrome P450 family 17 polypeptide 2/0.447
4xumIMNPeroxisome proliferator-activated receptor gamma/0.447
5cnoANPEpidermal growth factor receptor2.7.10.10.447
1dhrNADDihydropteridine reductase1.5.1.340.446
1fm4DXCMajor pollen allergen Bet v 1-L/0.446
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.446
1pyePM1Cyclin-dependent kinase 22.7.11.220.446
1w6hTITPlasmepsin-23.4.23.390.446
1y0s331Peroxisome proliferator-activated receptor delta/0.446
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.446
2uzbC75Cyclin-dependent kinase 22.7.11.220.446
2wedPP6Penicillopepsin-13.4.23.200.446
2yn8STUEphrin type-B receptor 42.7.10.10.446
3gu6ADPDeath-associated protein kinase 12.7.11.10.446
3hllI45Mitogen-activated protein kinase 14/0.446
3jynNDPQuinone oxidoreductase/0.446
3linE13Protease/0.446
3qqhX0ACyclin-dependent kinase 22.7.11.220.446
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.446
3ufnROCGag-Pol polyprotein/0.446
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.446
3vryB43Tyrosine-protein kinase HCK2.7.10.20.446
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.446
4a6bQG8Gag-Pol polyprotein3.4.23.160.446
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.446
4dqf017Gag-Pol polyprotein/0.446
4kb81QOCasein kinase I isoform delta2.7.11.10.446
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.446
5a3cNADSIR2 family protein/0.446
1hvrXK2Gag-Pol polyprotein/0.445
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2duv371Cyclin-dependent kinase 22.7.11.220.445
2ien017Gag-Pol polyprotein3.4.23.160.445
2igoFADPyranose 2-oxidase/0.445
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.445
2r43G3GGag-Pol polyprotein3.4.23.160.445
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.445
2xx91NFGlutamate receptor 2/0.445
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.445
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.445
3cyxROCGag-Pol polyprotein3.4.23.160.445
3ddpRC8Cyclin-dependent kinase 22.7.11.220.445
3orkAGSSerine/threonine protein kinase/0.445
3qaiXNNKetohexokinase/0.445
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.445
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.445
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.445
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.445
4btjATPTau-tubulin kinase 12.7.11.10.445
4c4g7RODual specificity protein kinase TTK2.7.12.10.445
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.445
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.445
4fod0UVALK tyrosine kinase receptor2.7.10.10.445
4g2fC07Ephrin type-A receptor 32.7.10.10.445
4g7gVFVLanosterol 14-alpha-demethylase/0.445
4id71G0Activated CDC42 kinase 1/0.445
4jq9FADDihydrolipoyl dehydrogenase/0.445
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.445
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1hvlA76Gag-Pol polyprotein/0.444
1k6tXN1Gag-Pol polyprotein3.4.23.160.444
2bb9AKCGag-Pol polyprotein3.4.23.160.444
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.444
2izsBRQCasein kinase I isoform gamma-32.7.11.10.444
2q7vFADThioredoxin reductase/0.444
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.444
2qnqQN3Gag-Pol polyprotein3.4.23.160.444
2xrwANPMitogen-activated protein kinase 82.7.11.240.444
3d1yROCGag-Pol polyprotein3.4.23.160.444
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.444
3icsCOACoenzyme A disulfide reductase/0.444
3il1B5DGlutamate receptor 2/0.444
3ral04ZCyclin-dependent kinase 22.7.11.220.444
3sm2478Putative gag-pro-pol polyprotein/0.444
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.444
3unj0BXCyclin-dependent kinase 22.7.11.220.444
3unk0BYCyclin-dependent kinase 22.7.11.220.444
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.444
3vf80JETyrosine-protein kinase SYK2.7.10.20.444
3zptM8YGag-Pol polyprotein3.4.23.160.444
4c02TAKActivin receptor type-12.7.11.300.444
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.444
4g160VMCasein kinase I isoform gamma-32.7.11.10.444
4iva1J5Tyrosine-protein kinase JAK2/0.444
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.444
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.444
4xgxADPFAD:protein FMN transferase/0.444
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.444
5cmsAPRO-acetyl-ADP-ribose deacetylase/0.444
1jld0PPGag-Pol polyprotein/0.443
1k7l544Peroxisome proliferator-activated receptor alpha/0.443
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.443
2b60RITPol polyprotein/0.443
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.443
2itpAEEEpidermal growth factor receptor2.7.10.10.443
2p3b3TLV-1 PROTEASE protein/0.443
2p3b3TLV-1 protease/0.443
2pwcG3GGag-Pol polyprotein3.4.23.160.443
2wihP48Cyclin-dependent kinase 22.7.11.220.443
3dk1G05Gag-Pol polyprotein3.4.23.160.443
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.443
3in6FMNUncharacterized protein/0.443
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
3k4vROCGag-Pol polyprotein3.4.23.160.443
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3lzv017Gag-Pol polyprotein3.4.23.160.443
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.443
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.443
3ormAGSSerine/threonine protein kinase/0.443
3oxv478Gag-Pol polyprotein3.4.23.160.443
3pxkPXKFocal adhesion kinase 12.7.10.20.443
3r9hZ67Cyclin-dependent kinase 22.7.11.220.443
3r9uFADThioredoxin reductase/0.443
3ttiKBIMitogen-activated protein kinase 102.7.11.240.443
3vqsJT1Genome polyprotein/0.443
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.443
4e200MYNon-receptor tyrosine-protein kinase TYK22.7.10.20.443
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4hegG52Gag-Pol polyprotein3.4.23.160.443
4jqh1MFAlr2278 protein/0.443
4mwhATPCasein kinase II subunit alpha2.7.11.10.443
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
4qmySTUSerine/threonine-protein kinase 242.7.11.10.443
4qmzB49Serine/threonine-protein kinase 242.7.11.10.443
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
5hwsNAP2-dehydropantoate 2-reductase/0.443
1gqtACPRibokinase/0.442
1t7i017Gag-Pol polyprotein3.4.23.160.442
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.442
2j0j4STFocal adhesion kinase 12.7.10.20.442
2vwz7X6Ephrin type-B receptor 42.7.10.10.442
2xru400Aurora kinase A2.7.11.10.442
2xyuQ9GEphrin type-A receptor 42.7.10.10.442
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.442
3bgcLJHGag-Pol polyprotein3.4.23.160.442
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.442
3el9DR7Gag-Pol polyprotein3.4.23.160.442
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.442
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.442
3p7nFMNLight-activated DNA-binding protein EL222/0.442
3qtrX36Cyclin-dependent kinase 22.7.11.220.442
3vt8YI3Vitamin D3 receptor/0.442
4bcpT3CCyclin-dependent kinase 22.7.11.220.442
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.442
4ktc1X3Genome polyprotein3.4.21.980.442
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.442
1gij2PUCyclin-dependent kinase 22.7.11.220.441
1ivq0PXGag-Pol polyprotein/0.441
1k6vXN2Gag-Pol polyprotein3.4.23.160.441
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.441
2c475IDCasein kinase I isoform gamma-2/0.441
2fdd385Pol protein/0.441
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.441
2w3bNDPDihydrofolate reductase1.5.1.30.441
2xvdAS6Ephrin type-B receptor 42.7.10.10.441
3a1nNADNDP-sugar epimerase/0.441
3bbrBHYGlutamate receptor 2/0.441
3dxjNE6DNA-directed RNA polymerase subunit beta/0.441
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.441
3mdvCL6Cholesterol 24-hydroxylase/0.441
3nwq2NCGag-Pol polyprotein3.4.23.160.441
3oev3OEProteasome subunit beta type-53.4.25.10.441
3oev3OEProteasome subunit beta type-63.4.25.10.441
3qa2XNAKetohexokinase/0.441
3qtuX44Cyclin-dependent kinase 22.7.11.220.441
3sa8K83Protease/0.441
3tdvGDPGentamicin resistance protein/0.441
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.441
4acxS8ZBeta-secretase 13.4.23.460.441
4b99R4LMitogen-activated protein kinase 72.7.11.240.441
4ei40Q2Tyrosine-protein kinase JAK1/0.441
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4hgs15GCasein kinase I isoform gamma-32.7.11.10.441
4ib4ERM5-hydroxytryptamine receptor 2B/0.441
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4oavACP2-5A-dependent ribonuclease3.1.260.441
4zohFADPutative oxidoreductase FAD-binding subunit/0.441
5br4NADLactaldehyde reductase1.1.1.770.441
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1h1pCMGCyclin-dependent kinase 22.7.11.220.440
1h1q2A6Cyclin-dependent kinase 22.7.11.220.440
1ig1ANPDeath-associated protein kinase 12.7.11.10.440
1knuYPAPeroxisome proliferator-activated receptor gamma/0.440
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.440
2b1pAIZMitogen-activated protein kinase 102.7.11.240.440
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.440
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.440
2hw2RFPRifampin ADP-ribosyl transferase/0.440
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.440
2i0aMUIProtease/0.440
2j0m4STFocal adhesion kinase 12.7.10.20.440
2npaMMBPeroxisome proliferator-activated receptor alpha/0.440
2pk5075Protease/0.440
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.440
2xlsFADPutative flavin-containing monooxygenase/0.440
2znpK55Peroxisome proliferator-activated receptor delta/0.440
3el51UNGag-Pol polyprotein/0.440
3qxpX64Cyclin-dependent kinase 22.7.11.220.440
3s3r0IWCathepsin B-like peptidase (C01 family)/0.440
3sf6FDAGlutaryl-CoA dehydrogenase/0.440
3t2kFADSulfide-quinone reductase/0.440
3zsgT75Mitogen-activated protein kinase 14/0.440
4a6cQG9Gag-Pol polyprotein3.4.23.160.440
4acm7YGCyclin-dependent kinase 22.7.11.220.440
4bbfO19Tyrosine-protein kinase JAK2/0.440
4fv9E71Mitogen-activated protein kinase 12.7.11.240.440
4h3g10QBeta-secretase 13.4.23.460.440
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.440
4j97ACPFibroblast growth factor receptor 2/0.440
5cvhADPCasein kinase II subunit alpha2.7.11.10.440