Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 1.000 | |
2a92 | NAI | L-lactate dehydrogenase | / | 0.483 | |
4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.465 | |
2aa3 | AP0 | L-lactate dehydrogenase | / | 0.454 | |
4ajo | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
1ie3 | NAD | Malate dehydrogenase | / | 0.444 | |
4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 |