Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4l4sNAIL-lactate dehydrogenase A chain1.1.1.27

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4l4sNAIL-lactate dehydrogenase A chain1.1.1.271.000
2a92NAIL-lactate dehydrogenase/0.483
4ajp88NL-lactate dehydrogenase A chain1.1.1.270.465
2aa3AP0L-lactate dehydrogenase/0.454
4ajo88NL-lactate dehydrogenase A chain1.1.1.270.451
1ie3NADMalate dehydrogenase/0.444
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.440