sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4kub | COA | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4kub | COA | Uncharacterized protein | / | 1.000 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.649 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.521 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.518 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.516 | |
| 4oad | CLM | Uncharacterized protein | / | 0.504 | |
| 3f8k | COA | Uncharacterized protein | / | 0.498 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.494 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.491 | |
| 4oae | CLM | Uncharacterized protein | / | 0.491 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.490 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.489 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.486 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.486 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.481 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.473 | |
| 2wpx | ACO | Orf14 | / | 0.472 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.469 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.468 | |
| 2wpw | ACO | Orf14 | / | 0.467 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.465 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.463 | |
| 4jxr | ACO | Acetyltransferase | / | 0.459 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.454 | |
| 1s7n | COA | Acetyl transferase | / | 0.452 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.452 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.452 | |
| 3sxn | COA | N-acetyltransferase Eis | / | 0.451 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.451 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.447 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.444 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.443 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 4r57 | ACO | Spermidine N(1)-acetyltransferase | / | 0.443 |