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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4knjE1FCarbonic anhydrase 24.2.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4knjE1FCarbonic anhydrase 24.2.1.11.000
1oq5CELCarbonic anhydrase 24.2.1.10.806
3m98E02Carbonic anhydrase 24.2.1.10.775
3myqE27Carbonic anhydrase 24.2.1.10.775
3mmfD9HCarbonic anhydrase 24.2.1.10.769
4kniE1ECarbonic anhydrase 24.2.1.10.763
3s8xE59Carbonic anhydrase 24.2.1.10.762
4mo82VQCarbonic anhydrase 24.2.1.10.758
4itp1GDCarbonic anhydrase 24.2.1.10.751
3saxE50Carbonic anhydrase 24.2.1.10.747
3ffpLC1Carbonic anhydrase 24.2.1.10.738
2wehFB1Carbonic anhydrase 24.2.1.10.737
3s9tE49Carbonic anhydrase 24.2.1.10.732
2eu3FF3Carbonic anhydrase 24.2.1.10.728
3mhiJ90Carbonic anhydrase 24.2.1.10.728
3sbiE90Carbonic anhydrase 24.2.1.10.727
3m2nJ74Carbonic anhydrase 24.2.1.10.725
3oikWZBCarbonic anhydrase 24.2.1.10.721
1g52F2BCarbonic anhydrase 24.2.1.10.720
3m2yBE0Carbonic anhydrase 24.2.1.10.720
3mnaDWHCarbonic anhydrase 24.2.1.10.720
3eft3BSCarbonic anhydrase 24.2.1.10.714
2powI7CCarbonic anhydrase 24.2.1.10.710
3mhoJ43Carbonic anhydrase 24.2.1.10.706
1oknSTBCarbonic anhydrase 24.2.1.10.703
3m96E38Carbonic anhydrase 24.2.1.10.703
3oimVZ5Carbonic anhydrase 24.2.1.10.703
1zsbAZMCarbonic anhydrase 24.2.1.10.700
4itoMPXCarbonic anhydrase 24.2.1.10.700
1kwrSG2Carbonic anhydrase 24.2.1.10.696
3b4fTUOCarbonic anhydrase 24.2.1.10.687
3oysOYSCarbonic anhydrase 24.2.1.10.687
2wegFBVCarbonic anhydrase 24.2.1.10.685
3n0nP9BCarbonic anhydrase 24.2.1.10.685
3sbhE65Carbonic anhydrase 24.2.1.10.681
3mzcS6ICarbonic anhydrase 24.2.1.10.678
1oklMNSCarbonic anhydrase 24.2.1.10.677
1if4FBSCarbonic anhydrase 24.2.1.10.676
2h15B19Carbonic anhydrase 24.2.1.10.675
3qykIE2Carbonic anhydrase 24.2.1.10.674
4bf6X0QCarbonic anhydrase 24.2.1.10.674
3f4xKLTCarbonic anhydrase 24.2.1.10.671
3k2fNKXCarbonic anhydrase 24.2.1.10.671
3l14I7BCarbonic anhydrase 24.2.1.10.670
1if6FBUCarbonic anhydrase 24.2.1.10.668
1i8zINLCarbonic anhydrase 24.2.1.10.665
3n3jWWVCarbonic anhydrase 24.2.1.10.665
1g1dFSBCarbonic anhydrase 24.2.1.10.661
3dd82C7Carbonic anhydrase 24.2.1.10.660
3m5eJDRCarbonic anhydrase 24.2.1.10.658
3t85SG7Carbonic anhydrase 24.2.1.10.656
1i90INMCarbonic anhydrase 24.2.1.10.654
4ilx1EZCarbonic anhydrase 24.2.1.10.654
1bnmAL8Carbonic anhydrase 24.2.1.10.653
3po6DT9Carbonic anhydrase 24.2.1.10.652
3nb5R21Carbonic anhydrase 24.2.1.10.651
1g4jFFBCarbonic anhydrase 24.2.1.10.648
4k13ETSCarbonic anhydrase 24.2.1.10.648
5fltVJJCarbonic anhydrase 24.2.1.10.647
3n4bWWZCarbonic anhydrase 24.2.1.10.645
2wejFB2Carbonic anhydrase 24.2.1.10.644
4iwz1GOCarbonic anhydrase 24.2.1.10.643
1g54FFBCarbonic anhydrase 24.2.1.10.642
2weoFBWCarbonic anhydrase 24.2.1.10.636
3ml2SU0Carbonic anhydrase 24.2.1.10.635
3kigDA4Carbonic anhydrase 24.2.1.10.631
3oy0OY0Carbonic anhydrase 24.2.1.10.631
1bn4AL9Carbonic anhydrase 24.2.1.10.630
3hkuTORCarbonic anhydrase 24.2.1.10.630
1bnnAL1Carbonic anhydrase 24.2.1.10.627
3d8wD8WCarbonic anhydrase 24.2.1.10.627
3m40J45Carbonic anhydrase 24.2.1.10.627
1cnyEG3Carbonic anhydrase 24.2.1.10.624
3dccD9ZCarbonic anhydrase 24.2.1.10.624
4bf19FKCarbonic anhydrase 24.2.1.10.621
1bn1AL5Carbonic anhydrase 24.2.1.10.620
1kwqSG1Carbonic anhydrase 24.2.1.10.620
1okmSABCarbonic anhydrase 24.2.1.10.619
1bnvAL7Carbonic anhydrase 24.2.1.10.618
1ttm667Carbonic anhydrase 24.2.1.10.618
3dazMZMCarbonic anhydrase 24.2.1.10.616
3dd0EZLCarbonic anhydrase 24.2.1.10.616
3mhlJ71Carbonic anhydrase 24.2.1.10.616
3p5lIT5Carbonic anhydrase 24.2.1.10.616
1if7SBRCarbonic anhydrase 24.2.1.10.615
1eouSMSCarbonic anhydrase 24.2.1.10.613
3t84SG6Carbonic anhydrase 24.2.1.10.613
3ni5C1HCarbonic anhydrase 24.2.1.10.611
3t82SG4Carbonic anhydrase 24.2.1.10.611
4pxxCHDCarbonic anhydrase 24.2.1.10.609
3m67E36Carbonic anhydrase 24.2.1.10.605
3betCTFCarbonic anhydrase 24.2.1.10.603
1ydaAZMCarbonic anhydrase 24.2.1.10.602
3rz8RZ8Carbonic anhydrase 24.2.1.10.602
4dz7D02Carbonic anhydrase 24.2.1.10.602
3igpDT7Carbonic anhydrase 24.2.1.10.601
4m2vBZ1Carbonic anhydrase 24.2.1.10.600
1bntAL2Carbonic anhydrase 24.2.1.10.599
4kap1QVCarbonic anhydrase 24.2.1.10.596
3n2pAYXCarbonic anhydrase 24.2.1.10.593
4n16CHDCarbonic anhydrase 24.2.1.10.592
4m2rBZ1Carbonic anhydrase 24.2.1.10.590
1i91INQCarbonic anhydrase 24.2.1.10.589
3d9zD9ZCarbonic anhydrase 24.2.1.10.589
3oyqOYQCarbonic anhydrase 24.2.1.10.587
2wd2MS5Carbonic anhydrase 24.2.1.10.586
3dcsMZMCarbonic anhydrase 24.2.1.10.582
4k0tD9ZCarbonic anhydrase 24.2.1.10.582
1a42BZUCarbonic anhydrase 24.2.1.10.579
1cnwEG1Carbonic anhydrase 24.2.1.10.579
1xq04TRCarbonic anhydrase 24.2.1.10.579
3dcwEZLCarbonic anhydrase 24.2.1.10.579
1if8SBSCarbonic anhydrase 24.2.1.10.576
1xpz4TZCarbonic anhydrase 24.2.1.10.573
3mhcARZCarbonic anhydrase 24.2.1.10.572
1bnwTPDCarbonic anhydrase 24.2.1.10.570
2h4nAZMCarbonic anhydrase 24.2.1.10.568
4kp8E1GCarbonic anhydrase 124.2.1.10.568
3dc3AZMCarbonic anhydrase 24.2.1.10.567
1cilETSCarbonic anhydrase 24.2.1.10.564
2x7tWZBCarbonic anhydrase 24.2.1.10.564
3mdzEZLCarbonic anhydrase 74.2.1.10.563
3zncBZ1Carbonic anhydrase 44.2.1.10.560
2x7uWZACarbonic anhydrase 24.2.1.10.552
1bnuAL3Carbonic anhydrase 24.2.1.10.541
1cnxEG2Carbonic anhydrase 24.2.1.10.541
1i9qIOFCarbonic anhydrase 24.2.1.10.540
3dbuD8WCarbonic anhydrase 24.2.1.10.538
4kp5E1FCarbonic anhydrase 124.2.1.10.538
3bl1BL1Carbonic anhydrase 24.2.1.10.534
1bnqAL4Carbonic anhydrase 24.2.1.10.533
3f7uAG4Carbonic anhydrase 44.2.1.10.531
3f7bAG5Carbonic anhydrase 44.2.1.10.528
1bn3AL6Carbonic anhydrase 24.2.1.10.521
1if5FBTCarbonic anhydrase 24.2.1.10.520
2g247IGRenin3.4.23.150.519
2q1qOSPCarbonic anhydrase 24.2.1.10.519
3v2jAZMCarbonic anhydrase 24.2.1.10.518
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.517
1jd0AZMCarbonic anhydrase 124.2.1.10.517
4k0zMZMCarbonic anhydrase 24.2.1.10.513
3h3qH13Collagen type IV alpha-3-binding protein/0.511
4lu3AZMCarbonic anhydrase 144.2.1.10.511
1w6hTITPlasmepsin-23.4.23.390.509
1rj6AZMCarbonic anhydrase 144.2.1.10.508
3vydVYDRenin3.4.23.150.507
3gwfNAPCyclohexanone monooxygenase/0.506
4a83DXCMajor pollen allergen Bet v 1-A/0.504
4m9aFDAAcyl-CoA dehydrogenase/0.503
4xiwAZMCarbonic anhydrase, alpha type/0.503
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.502
4ca83ESAngiotensin-converting enzyme3.4.15.10.500
4knmE1ECarbonic anhydrase 134.2.1.10.500
4ey6GNTAcetylcholinesterase3.1.1.70.499
2pncCLUPrimary amine oxidase, liver isozyme/0.498
3ziuLSSLeucyl-tRNA synthetase/0.498
1x1aSAMC-20 methyltransferase/0.497
4m83ERYOleandomycin glycosyltransferase2.4.10.496
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.496
1xagNAD3-dehydroquinate synthase/0.495
2rqfJH3Hemolymph juvenile hormone binding protein/0.495
4x5sAZMCarbonic anhydrase (Carbonate dehydratase)/0.495
4a81DXCMajor pollen allergen Bet v 1-A/0.494
1qoqIGPTryptophan synthase alpha chain/0.493
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.493
1h50FMNPentaerythritol tetranitrate reductase/0.492
2a9y26AAdenosine kinase2.7.1.200.492
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
3lqfNADGalactitol dehydrogenase/0.492
4l0qNADAlcohol dehydrogenase class-3/0.492
4h9tHL4Phosphotriesterase/0.491
4hu1V13Carbonic anhydrase 134.2.1.10.491
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.490
1a5bIGPTryptophan synthase alpha chain/0.489
4fhf0TTSpore photoproduct lyase/0.489
1c7oPPGHemolysin/0.488
1xddAAYIntegrin alpha-L/0.488
2bf4FMNNADPH--cytochrome P450 reductase/0.488
2g1r3IGRenin3.4.23.150.488
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.488
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.488
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.488
1fm4DXCMajor pollen allergen Bet v 1-L/0.487
1xe65FPPlasmepsin-23.4.23.390.487
2rh9IGPTryptophan synthase alpha chain/0.487
4ycoFMNtRNA-dihydrouridine(16) synthase/0.487
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.486
2c12FADNitroalkane oxidase1.7.3.10.486
2r0cFADPutative FAD-monooxygenase/0.486
3a0tADPSensor histidine kinase/0.486
4eb5PLPCysteine desulfurase IscS 2/0.486
1k8y13PTryptophan synthase alpha chain/0.485
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.485
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.485
1xe55FEPlasmepsin-23.4.23.390.484
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.484
1fy7COAHistone acetyltransferase ESA1/0.483
1kh3ANPArgininosuccinate synthase/0.483
2g263LGRenin3.4.23.150.483
2gv8NDPThiol-specific monooxygenase1.14.130.483
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.483
3fw3ETSCarbonic anhydrase 44.2.1.10.483
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.483
1h22E10Acetylcholinesterase3.1.1.70.482
2ikuLIYRenin3.4.23.150.482
2il2LIXRenin3.4.23.150.482
1rftPXMPyridoxal kinase2.7.1.350.481
2cekN8TAcetylcholinesterase3.1.1.70.481
2g1y5IGRenin3.4.23.150.481
3p74FMNPentaerythritol tetranitrate reductase/0.481
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.481
4uovAZMCarbonate dehydratase/0.481
2g1s4IGRenin3.4.23.150.480
2givACOHistone acetyltransferase KAT8/0.480
2qimZEAClass 10 plant pathogenesis-related protein/0.480
3akn11DFatty acid-binding protein, intestinal/0.480
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
3h3t16HCollagen type IV alpha-3-binding protein/0.480
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.480
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.480
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.480
4bfzZVZPantothenate kinase2.7.1.330.480
4giu636Anthranilate phosphoribosyltransferase/0.480
2a94AP0L-lactate dehydrogenase1.1.1.270.479
3lxeTORCarbonic anhydrase 14.2.1.10.479
4a862ANMajor pollen allergen Bet v 1-A/0.479
4a8v2ANMajor pollen allergen Bet v 1-J/0.479
1kfbIGPTryptophan synthase alpha chain/0.478
1mjbACOHistone acetyltransferase ESA1/0.478
1xvaSAMGlycine N-methyltransferase2.1.1.200.478
2xveFADPutative flavin-containing monooxygenase/0.478
3fhxPXLPyridoxal kinase2.7.1.350.478
3x2eNAIAdenosylhomocysteinase/0.478
1amoFMNNADPH--cytochrome P450 reductase/0.477
1h51FMNPentaerythritol tetranitrate reductase/0.477
1qrpHH0Pepsin A-43.4.23.10.477
2x06NADL-sulfolactate dehydrogenase/0.477
2zbaZBATrichothecene 3-O-acetyltransferase/0.477
3f03FMNPentaerythritol tetranitrate reductase/0.477
3qt62P0Mevalonate diphosphate decarboxylase/0.477
4gd40WSLysine-specific demethylase 4A1.14.110.477
4to0DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.477
1mjaCOAHistone acetyltransferase ESA1/0.476
2bn4FMNNADPH--cytochrome P450 reductase/0.476
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.476
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.476
3qe2FMNNADPH--cytochrome P450 reductase/0.476
4blrUTPNTPase P4/0.476
1psa0ZLPepsin A3.4.23.10.475
1qtiGNTAcetylcholinesterase3.1.1.70.475
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.475
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.475
2iko7IGRenin3.4.23.150.475
2whqHI6Acetylcholinesterase3.1.1.70.475
5irnADPNucleotide binding oligomerization domain containing 2/0.475
1bwsNDPGDP-L-fucose synthase/0.474
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.474
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.474
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.474
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
5a0112VO-glycosyltransferase/0.474
1rneC60Renin3.4.23.150.473
1vyrFMNPentaerythritol tetranitrate reductase/0.473
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.473
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.473
3ibqATPPyridoxal kinase/0.472
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.472
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.472
1h63FMNPentaerythritol tetranitrate reductase/0.471
1kp3ATPArgininosuccinate synthase6.3.4.50.471
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.471
2ct8MSPMethionine--tRNA ligase6.1.1.100.471
2uxoTACHTH-type transcriptional regulator TtgR/0.471
2xuoTZ4Acetylcholinesterase3.1.1.70.471
3tr05GPGuanylate kinase/0.471
3uu114BAnthranilate phosphoribosyltransferase/0.471
3wagTYDGlycosyltransferase/0.471
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.471
1n2jPAFPantothenate synthetase6.3.2.10.470
1tehNADAlcohol dehydrogenase class-31.1.1.10.470
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.470
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.470
2g226IGRenin3.4.23.150.470
4ax9N5NProthrombin3.4.21.50.470
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.470
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.470
5fl49FKCarbonic anhydrase 94.2.1.10.470
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.469
2b58COADiamine acetyltransferase 1/0.469
2g8yNADHydroxycarboxylate dehydrogenase B/0.469
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.469
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.469
1drhNAPDihydrofolate reductase1.5.1.30.468
1m8gNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.468
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.468
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.468
2b3vACODiamine acetyltransferase 1/0.468
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.468
2g1o2IGRenin3.4.23.150.468
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.468
4fse0VABeta-secretase 13.4.23.460.468
1votHUPAcetylcholinesterase3.1.1.70.467
2e15SAHDiphthine synthase/0.467
2g21L1BRenin3.4.23.150.467
2i4qUA4Renin3.4.23.150.467
2w6cBM4Acetylcholinesterase3.1.1.70.467
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.467
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.467
3oetNADErythronate-4-phosphate dehydrogenase/0.467
4eb7PLPCysteine desulfurase IscS 2/0.467
4f5yC2EStimulator of interferon genes protein/0.467
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.467
4qzuRTLRetinol-binding protein 2/0.467
4u7wNDPMxaA/0.467
4v12POGMaoC like domain protein/0.467
5jscFADPutative acyl-CoA dehydrogenase/0.467
1cf3FADGlucose oxidase1.1.3.40.466
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.466
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.466
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
2rlcCHDCholoylglycine hydrolase3.5.1.240.466
2v16C47Renin3.4.23.150.466
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
2z9dFMNFMN-dependent NADH-azoreductase/0.466
3in6FMNUncharacterized protein/0.466
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.466
3v2uATPProtein GAL3/0.466
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.466
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.466
4gdcNDPUDP-galactopyranose mutase/0.466
4mlp2CXCryptochrome-2/0.466
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.466
1e66HUXAcetylcholinesterase3.1.1.70.465
1me6IVSPlasmepsin-23.4.23.390.465
2bjfDXCCholoylglycine hydrolase3.5.1.240.465
2g1n1IGRenin3.4.23.150.465
2zsaADPPantothenate kinase2.7.1.330.465
3fr5I4AFatty acid-binding protein, adipocyte/0.465
3i25MV7Beta-secretase 13.4.23.460.465
3lpkZ76Beta-secretase 13.4.23.460.465
4a84DXCMajor pollen allergen Bet v 1-A/0.465
4hn1TYDdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.465
4ke01R8Beta-secretase 13.4.23.460.465
1ex75GPGuanylate kinase2.7.4.80.464
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.464
1kp2ATPArgininosuccinate synthase6.3.4.50.464
1od10QSEndothiapepsin3.4.23.220.464
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
2abbFMNPentaerythritol tetranitrate reductase/0.464
2c29NAPDihydroflavonol 4-reductase/0.464
2i7pACOPantothenate kinase 32.7.1.330.464
2rhgIGPTryptophan synthase alpha chain/0.464
2x91LPRAngiotensin-converting enzyme3.4.15.10.464
2xuiTZ5Acetylcholinesterase3.1.1.70.464
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3g70A5TRenin3.4.23.150.464
3own3OWRenin3.4.23.150.464
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.464
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.464
4iae1DXAlr2278 protein/0.464
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.464
5kwvANPPantothenate synthetase/0.464
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.463
1v0jFADUDP-galactopyranose mutase5.4.99.90.463
2ab8MTPAdenosine kinase2.7.1.200.463
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.463
3br3ETHTH-type transcriptional regulator QacR/0.463
3ivxFG6Pantothenate synthetase6.3.2.10.463
3lqsPSZD-alanine aminotransferase2.6.1.210.463
3p80P80Pentaerythritol tetranitrate reductase/0.463
3qfrFMNNADPH--cytochrome P450 reductase/0.463
3s5wFADL-ornithine N(5)-monooxygenase/0.463
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.463
4b4w9L9Bifunctional protein FolD/0.463
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.463
1beuIPLTryptophan synthase alpha chain/0.462
1u1f183Uridine phosphorylase2.4.2.30.462
2oapANPType II secretion system protein (GspE-2)/0.462
3d91REMRenin3.4.23.150.462
3kmxG00Beta-secretase 13.4.23.460.462
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.462
1ja0FMNNADPH--cytochrome P450 reductase/0.461
1og4NAIT-cell ecto-ADP-ribosyltransferase 2/0.461
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.461
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.461
1tl7ONMAdenylate cyclase type 2/0.461
1tl7ONMAdenylate cyclase type 5/0.461
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.461
2fxfACODiamine acetyltransferase 1/0.461
2hk9NAPShikimate dehydrogenase (NADP(+))/0.461
3rvhHQ2Lysine-specific demethylase 4A1.14.110.461
4frkDWDBeta-secretase 13.4.23.460.461
1b2lNDCAlcohol dehydrogenase1.1.1.10.460
1e800GQEndothiapepsin3.4.23.220.460
1gpnHUBAcetylcholinesterase3.1.1.70.460
1n77ATPGlutamate--tRNA ligase6.1.1.170.460
1obnASVIsopenicillin N synthase1.21.3.10.460
2d29FADAcyl-CoA dehydrogenase/0.460
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.460
3bk2U5PRibonuclease J/0.460
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.460
3jziJZLBiotin carboxylase6.3.4.140.460
3lb8FADPutidaredoxin reductase1.18.1.50.460
3wczNAPAldo-keto reductase AKR2E4/0.460
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.460
4bfvZVVPantothenate kinase2.7.1.330.460
4dc0NDPPutative ketoacyl reductase1.3.10.460
4j7hTRHPCZA361.3/0.460
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.460
1cq8PY6Aspartate aminotransferase2.6.1.10.459
1e81M91Endothiapepsin3.4.23.220.459
1lf2R37Plasmepsin-23.4.23.390.459
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.459
1rfuADPPyridoxal kinase2.7.1.350.459
1w4lGL8Acetylcholinesterase3.1.1.70.459
1yvfPH7Polyprotein/0.459
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.459
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.459
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.459
3cic316Beta-secretase 13.4.23.460.459
3h3r14HCollagen type IV alpha-3-binding protein/0.459
3zv7NHGAcetylcholinesterase3.1.1.70.459
4bf9FMNtRNA-dihydrouridine(16) synthase/0.459
4c49HCYCorticosteroid-binding globulin/0.459
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.459
4jicFMNGTN Reductase/0.459
4rquNADAlcohol dehydrogenase class-P/0.459
4to5DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.459
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.459
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.459
7stdCRPScytalone dehydratase4.2.1.940.459
1eveE20Acetylcholinesterase3.1.1.70.458
1ivsVAAValine--tRNA ligase6.1.1.90.458
1t2cNAIL-lactate dehydrogenase1.1.1.270.458
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.458
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.458
2jb4A14Isopenicillin N synthase1.21.3.10.458
2vbdV10Isopenicillin N synthase1.21.3.10.458
2vijC44Beta-secretase 13.4.23.460.458
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.458
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.458
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.458
3ixp834Ecdysone receptor/0.458
3l6jZ90Alr2278 protein/0.458
4a87NARMajor pollen allergen Bet v 1-A/0.458
4knnE1FCarbonic anhydrase 134.2.1.10.458
4q0kGA3Phytohormone-binding protein/0.458
4w5kPLPAspartate aminotransferase, mitochondrial/0.458
1cjuFOKAdenylate cyclase type 2/0.457
1cjuFOKAdenylate cyclase type 5/0.457
1fmjRTLRetinol dehydratase/0.457
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.457
1ve3SAMUncharacterized protein/0.457
2pauD5M5'-deoxynucleotidase YfbR/0.457
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.457
2ylzFADPhenylacetone monooxygenase1.14.13.920.457
3hl0NADMaleylacetate reductase/0.457
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3nl6TPSUncharacterized protein/0.457
3p62FMNPentaerythritol tetranitrate reductase/0.457
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.457
3vyfVYFRenin3.4.23.150.457
4dptAGSMevalonate diphosphate decarboxylase/0.457
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.457
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.457
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.457
4rvgTYDD-mycarose 3-C-methyltransferase/0.457
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.457
5jy1NADPutative short-chain dehydrogenase/reductase/0.457
1ay0TPPTransketolase 12.2.1.10.456
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.456
1n2iPAJPantothenate synthetase6.3.2.10.456
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.456
1w76GNTAcetylcholinesterase3.1.1.70.456
2cv2GSUGlutamate--tRNA ligase6.1.1.170.456
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.456
3oqkS52Renin3.4.23.150.456
3p8jFMNPentaerythritol tetranitrate reductase/0.456
3w3nRX8Toll-like receptor 8/0.456
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.456
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.456
4du6GTPGTP cyclohydrolase 1/0.456
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.456
4nv10FXFormyl transferase/0.456
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.456
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.455
1n2hPAJPantothenate synthetase6.3.2.10.455
1n5qTNCActVA 6 protein/0.455
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.455
1vbiNADMalate/L-lactate dehydrogenase family protein/0.455
1yb5NAPQuinone oxidoreductase1.6.5.50.455
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.455
2dc1NADProbable L-aspartate dehydrogenase/0.455
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.455
2jt2C90UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.455
2v58LZJBiotin carboxylase6.3.4.140.455
3h2sNDPPutative NADH-flavin reductase/0.455
3ioeA7DPantothenate synthetase6.3.2.10.455
3mj4FADUDP-galactopyranose mutase/0.455
3p67FMNPentaerythritol tetranitrate reductase/0.455
3prsRITEndothiapepsin3.4.23.220.455
3qwbNDPProbable quinone oxidoreductase1.6.5.50.455
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.455
4b1hAR6Poly(ADP-ribose) glycohydrolase3.2.1.1430.455
4bis8HQLysine-specific demethylase 4A1.14.110.455
4de2DN3Beta-lactamase/0.455
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.455
4lutDCSAlanine racemase/0.455
4n1gCEIObelin/0.455
4pzrCOAHistone acetyltransferase p300/0.455
1bil0IURenin3.4.23.150.454
1yw7A41Methionine aminopeptidase 2/0.454
1yw8A75Methionine aminopeptidase 2/0.454
1zdwFLVPrenyltransferase/0.454
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.454
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2w6zL21Biotin carboxylase6.3.4.140.454
2x3fAPCPantothenate synthetase/0.454
2xvw9NRSerum albumin/0.454
2z1qFADAcyl-CoA dehydrogenase/0.454
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3fhxPLPPyridoxal kinase2.7.1.350.454
3ge6FMNNitroreductase/0.454
3gw9VNILanosterol 14-alpha-demethylase/0.454
3k8q22APurine nucleoside phosphorylase2.4.2.10.454
3lpiZ74Beta-secretase 13.4.23.460.454
3q33ACOHistone acetyltransferase RTT1092.3.1.480.454
3qvpFADGlucose oxidase1.1.3.40.454
4b4vL34Bifunctional protein FolD/0.454
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.454
4fxy0W2Neurolysin, mitochondrial3.4.24.160.454
4ipw1G7Mycocyclosin synthase1.14.21.90.454
4rvfTYDD-mycarose 3-C-methyltransferase/0.454
4y3zF41Endothiapepsin3.4.23.220.454
4yaoFMNNADPH--cytochrome P450 reductase/0.454
1ankANPAdenylate kinase/0.453
1culFOKAdenylate cyclase type 2/0.453
1culFOKAdenylate cyclase type 5/0.453
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.453
1odcA8BAcetylcholinesterase3.1.1.70.453
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.453
1swtBTNStreptavidin/0.453
1udbUFGUDP-glucose 4-epimerase5.1.3.20.453
1w34FADFerredoxin--NADP reductase1.18.1.20.453
1wxjIPLTryptophan synthase alpha chain/0.453
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.453
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
3d2pCOAAmino-acid acetyltransferase/0.453
3ekuCY9Actin-5C/0.453
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.453
3f3sNADLambda-crystallin homolog/0.453
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.453
3ohh3HHBeta-secretase 13.4.23.460.453
4a802ANMajor pollen allergen Bet v 1-A/0.453
4e31JHZMethyltransferase/0.453
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.453
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1g6oADPCag alpha/0.452
1hb3SCVIsopenicillin N synthase1.21.3.10.452
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
2c20NADUDP-glucose 4-epimerase/0.452
2fs4PZ1Renin3.4.23.150.452
2idkC2FGlycine N-methyltransferase2.1.1.200.452
2vj7VG6Beta-secretase 13.4.23.460.452
2wzwNDPNitroreductase NfnB/0.452
2x3jATPAcsD/0.452
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.452
3p82FMNPentaerythritol tetranitrate reductase/0.452
3t7x4SHEndothiapepsin3.4.23.220.452
3tneRITCandidapepsin-13.4.23.240.452
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.452
4bfuZVUPantothenate kinase2.7.1.330.452
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.452
4i1iNADMalate dehydrogenase/0.452
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.451
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.451
1icqOPD12-oxophytodienoate reductase 11.3.1.420.451
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.451
1kqcFMNOxygen-insensitive NAD(P)H nitroreductase/0.451
1qorNDPQuinone oxidoreductase 1/0.451
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.451
1zg32HIIsoflavone 4'-O-methyltransferase/0.451
2dvlFADAcyl-CoA dehydrogenase/0.451
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.451
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.451
2q0lNAPThioredoxin reductase1.8.1.90.451
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.451
2y882ERPhosphoribosyl isomerase A5.3.1.160.451
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.451
3cid318Beta-secretase 13.4.23.460.451
3coy53HPantothenate synthetase6.3.2.10.451
3dr7GPDGDP-perosamine synthase/0.451
3fhyATPPyridoxal kinase2.7.1.350.451
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.451
3mj4URMUDP-galactopyranose mutase/0.451
3nutSAHPrecorrin-3 methylase/0.451
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3vsxR32Renin3.4.23.150.451
3wqmB29Diterpene synthase3.1.7.80.451
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.451
4esoNAPPutative oxidoreductase/0.451
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.451
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.451
4iah1DXAlr2278 protein/0.451
4jqh1MFAlr2278 protein/0.451
4rp8ASCAscorbate-specific PTS system EIIC component/0.451
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.451
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.451
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.450
1lkeDOGBilin-binding protein/0.450
1nzxNADAldehyde dehydrogenase, mitochondrial1.2.1.30.450
1rszDIHPurine nucleoside phosphorylase2.4.2.10.450
1towCRZFatty acid-binding protein, adipocyte/0.450
1udaUFGUDP-glucose 4-epimerase5.1.3.20.450
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.450
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.450
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.450
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
2zvcSAHPrecorrin-3 C17-methyltransferase/0.450
3af1GDPPantothenate kinase2.7.1.330.450
3cluFADElectron transfer flavoprotein subunit alpha/0.450
3imgBZ2Pantothenate synthetase6.3.2.10.450
3ixk929Beta-secretase 13.4.23.460.450
3n4l842Beta-secretase 13.4.23.460.450
3ojxFMNNADPH--cytochrome P450 reductase/0.450
3pvcFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.450
3rbaCODPhosphopantetheine adenylyltransferase/0.450
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.450
4e2wJHZMethyltransferase/0.450
4q71FADBifunctional protein PutA/0.450
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.450
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.450
4zowCLMMultidrug transporter MdfA/0.450
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.450
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.450
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.450
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.449
1g1aNADdTDP-glucose 4,6-dehydratase/0.449
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.449
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.449
1u65CP0Acetylcholinesterase3.1.1.70.449
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.449
2g274LGRenin3.4.23.150.449
2x8gFADThioredoxin glutathione reductase/0.449
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
3oesGNPGTPase RhebL1/0.449
3qviK95HAP protein/0.449
3tjzGNPADP-ribosylation factor 1/0.449
3uayADNPurine nucleoside phosphorylase DeoD-type/0.449
3vucHHERenin3.4.23.150.449
4c5oFADPutative monooxygenase/0.449
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.449
4m0f1YKAcetylcholinesterase3.1.1.70.449
4oqyNDP(S)-imine reductase/0.449
4p9dTMPDeoxycytidylate deaminase/0.449
4pzsACOHistone acetyltransferase p300/0.449
5dp2NAPCurF/0.449
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.448
1e82M90Endothiapepsin3.4.23.220.448
1eioGCHGastrotropin/0.448
1icqFMN12-oxophytodienoate reductase 11.3.1.420.448
1ja0FADNADPH--cytochrome P450 reductase/0.448
1kqbFMNOxygen-insensitive NAD(P)H nitroreductase/0.448
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.448
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.448
1wziNDPMalate dehydrogenase/0.448
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1zbdGTPRas-related protein Rab-3A/0.448
1zgbA1EAcetylcholinesterase3.1.1.70.448
2dvoITTdITP/XTP pyrophosphatase3.6.1.190.448
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.448
2irzI02Beta-secretase 13.4.23.460.448
3apwDP0Alpha-1-acid glycoprotein 2/0.448
3d4pNADL-lactate dehydrogenase 11.1.1.270.448
3dszLIZNeutrophil gelatinase-associated lipocalin/0.448
3gkaFMNN-ethylmaleimide reductase/0.448
3gwfFADCyclohexanone monooxygenase/0.448
3pqbVGPPutative oxidoreductase/0.448
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.448
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.448
3vswR31Renin3.4.23.150.448
4ejmNAPPutative zinc-binding dehydrogenase/0.448
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.448
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.448
4fizCUE17beta-hydroxysteroid dehydrogenase/0.448
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.448
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.447
1g45FSBCarbonic anhydrase 24.2.1.10.447
1icpFMN12-oxophytodienoate reductase 11.3.1.420.447
1tqf32PBeta-secretase 13.4.23.460.447
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.447
2ckmAA7Acetylcholinesterase3.1.1.70.447
2ejzSAHDiphthine synthase/0.447
2g20L1ARenin3.4.23.150.447
2iyfERYOleandomycin glycosyltransferase2.4.10.447
2qbuSAHPrecorrin-2 methyltransferase/0.447
2xfyACXBeta-amylase3.2.1.20.447
2zevB71Geranylgeranyl pyrophosphate synthase/0.447
3c3xNAPEugenol synthase 11.1.1.3180.447
3fp0FP015-O-acetyltransferase/0.447
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.447
4b2gV1NUncharacterized protein/0.447
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
4egbNADdTDP-glucose 4,6-dehydratase/0.447
4r81FMNPredicted NADH dehydrogenase/0.447
4tx9AMZPhosphoribosyl isomerase A/0.447
4xg1LLPDiaminopimelate decarboxylase/0.447
1bxsNADRetinal dehydrogenase 11.2.1.360.446
1cjtFOKAdenylate cyclase type 2/0.446
1cjtFOKAdenylate cyclase type 5/0.446
1kfcIPLTryptophan synthase alpha chain/0.446
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.446
1mbbEEBUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.446
1mj9COAHistone acetyltransferase ESA1/0.446
1necFMNOxygen-insensitive NAD(P)H nitroreductase10.446
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.446
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.446
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.446
2anb5GPGuanylate kinase2.7.4.80.446
2dxiATPGlutamate--tRNA ligase6.1.1.170.446
2ea2F77Methionine aminopeptidase 2/0.446
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.446
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.446
2j3qTFLAcetylcholinesterase3.1.1.70.446
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.446
2tohHBITyrosine 3-monooxygenase1.14.16.20.446
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
2yj5ATPCopper-transporting ATPase/0.446
2yxuATPPyridoxal kinase2.7.1.350.446
3atyFMNProstaglandin F2a synthase/0.446
3b9lAZZSerum albumin/0.446
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.446
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3h06VBPGlutamate receptor 2/0.446
3h3sH15Collagen type IV alpha-3-binding protein/0.446
3ivgFG5Pantothenate synthetase6.3.2.10.446
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
4g7gVFVLanosterol 14-alpha-demethylase/0.446
4jq4IMNAldo-keto reductase family 1 member C2/0.446
4lxk1YTBeta-secretase 13.4.23.460.446
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.446
5hg0SAMPantothenate synthetase/0.446
1hkuNADC-terminal-binding protein 11.1.10.445
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1pd9CO4Dihydrofolate reductase1.5.1.30.445
1r5gAO1Methionine aminopeptidase 2/0.445
1v453DGPurine nucleoside phosphorylase2.4.2.10.445
1w6rGNTAcetylcholinesterase3.1.1.70.445
1zrzBI1Protein kinase C iota type2.7.11.130.445
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2i7nACOPantothenate kinase 12.7.1.330.445
2j83BATUlilysin3.4.240.445
2v7qATPATP synthase subunit alpha, mitochondrial/0.445
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.445
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.445
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.445
2zvbSAHPrecorrin-3 C17-methyltransferase/0.445
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3juqAJDPhenazine biosynthesis protein A/B/0.445
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.445
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.445
3qgf46FGenome polyprotein2.7.7.480.445
3vilSA0Beta-glucosidase/0.445
4e0u0MVCyclic dipeptide N-prenyltransferase/0.445
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.445
4fsl0VBBeta-secretase 13.4.23.460.445
4iawLIZNeutrophil gelatinase-associated lipocalin/0.445
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.445
4pt0NADAldehyde dehydrogenase/0.445
4y380A9Endothiapepsin3.4.23.220.445
4y3jHICEndothiapepsin3.4.23.220.445
5cflC2EStimulator of interferon genes protein/0.445
1bwlFMNNADPH dehydrogenase 11.6.99.10.444
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.444
1ikiREYD-alanyl-D-alanine carboxypeptidase3.4.16.40.444
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.444
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1tkaN3TTransketolase 12.2.1.10.444
1u1d181Uridine phosphorylase2.4.2.30.444
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.444
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.444
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
2bjuIH4Plasmepsin-23.4.23.390.444
2fj1CTCTetracycline repressor protein class D/0.444
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.444
2j9lATPH(+)/Cl(-) exchange transporter 5/0.444
2jh5895Prothrombin3.4.21.50.444
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.444
2vq7NAPPutative flavin-containing monooxygenase/0.444
2wu4HBPAcetylcholinesterase3.1.1.70.444
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3eksCY9Actin-5C/0.444
3fr4F8AFatty acid-binding protein, adipocyte/0.444
3gvhNADMalate dehydrogenase/0.444
3ha7B32Hydroxymycolate synthase MmaA42.1.10.444
3l7gM44Xaa-Pro dipeptidase3.4.13.90.444
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.444
3ukoNADAlcohol dehydrogenase class-3/0.444
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.444
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.444
3zoiM2WIsopenicillin N synthase1.21.3.10.444
4d89BXDBeta-secretase 13.4.23.460.444
4du82P0Mevalonate diphosphate decarboxylase/0.444
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.444
4gl4NAIAlcohol dehydrogenase class-3/0.444
4id9NADPutative UDP-glucose 4-epimerase/0.444
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
4nbwNADShort-chain dehydrogenase/reductase SDR/0.444
4v2gITCTetracycline repressor protein class D/0.444
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1bim0QBRenin3.4.23.150.443
1e2nRCAThymidine kinase/0.443
1icvFMNOxygen-insensitive NAD(P)H nitroreductase/0.443
1mx0ANPType 2 DNA topoisomerase 6 subunit B/0.443
1qm5PLPMaltodextrin phosphorylase2.4.1.10.443
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.443
1tduDURThymidylate synthase/0.443
2cnsACORibosomal-protein-alanine acetyltransferase/0.443
2is0I03Beta-secretase 13.4.23.460.443
2ohvNHLGlutamate racemase/0.443
2v00V15Endothiapepsin3.4.23.220.443
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
2zhe13UProthrombin3.4.21.50.443
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.443
3hj9FMNUncharacterized protein/0.443
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.443
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3qfaFADThioredoxin reductase 1, cytoplasmic1.8.1.90.443
3t3q9PLCytochrome P450 2A61.14.130.443
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3x21FMNOxygen-insensitive NAD(P)H nitroreductase/0.443
4b68FADL-ornithine N(5)-monooxygenase/0.443
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4e2dFMNDehydrogenase/0.443
4e5pNADPhosphonate dehydrogenase1.20.1.10.443
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.443
4zweDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.443
1cqp803Integrin alpha-L/0.442
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1h65GDPTranslocase of chloroplast 343.6.50.442
1kkq471Peroxisome proliferator-activated receptor alpha/0.442
1mmkH4BPhenylalanine-4-hydroxylase1.14.16.10.442
1mxfMTXPutative pteridine reductase 2/0.442
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.442
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.442
1txtCAAHMG-CoA synthase/0.442
1u1cBAUUridine phosphorylase2.4.2.30.442
2a92NAIL-lactate dehydrogenase/0.442
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.442
2iviACWIsopenicillin N synthase1.21.3.10.442
2oegUPGUDP-glucose pyrophosphorylase/0.442
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
2v59LZKBiotin carboxylase6.3.4.140.442
2vutNADNitrogen metabolite repression protein nmrA/0.442
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.442
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.442
2xuqTZ4Acetylcholinesterase3.1.1.70.442
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.442
3atzFMNProstaglandin F2a synthase/0.442
3b1dPLSBetaC-S lyase/0.442
3b70NAPEnoyl reductase LovC10.442
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3dzvADPHydroxyethylthiazole kinase/0.442
3ewkFADSensory box histidine kinase/response regulator/0.442
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.442
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3otwCOAPhosphopantetheine adenylyltransferase/0.442
3pm1ETHTH-type transcriptional regulator QacR/0.442
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.442
3vtbTKAVitamin D3 receptor/0.442
3zeiAWHO-acetylserine sulfhydrylase/0.442
4b1rITCTetracycline repressor protein class D/0.442
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
4fud6UPUrokinase-type plasminogen activator3.4.21.730.442
4g8jTHMUridine phosphorylase/0.442
4ocvANPAminoglycoside phosphotransferase/0.442
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.442
1cjkFOKAdenylate cyclase type 2/0.441
1cjkFOKAdenylate cyclase type 5/0.441
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1gaxVAAValine--tRNA ligase6.1.1.90.441
1j49NADD-lactate dehydrogenase1.1.1.280.441
1mxiSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.441
1pl6572Sorbitol dehydrogenase1.1.1.140.441
1qrsATPGlutamine--tRNA ligase6.1.1.180.441
1x1dSAHC-20 methyltransferase/0.441
2a5kAZPReplicase polyprotein 1ab3.4.220.441
2abaSTRPentaerythritol tetranitrate reductase/0.441
2gstGPSGlutathione S-transferase Mu 12.5.1.180.441
2hveADPNucleoside diphosphate kinase A2.7.4.60.441
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.441
2lfoGCHFatty acid-binding protein, liver/0.441
2p8hMY9Beta-secretase 13.4.23.460.441
2r59PH0Leukotriene A-4 hydrolase3.3.2.60.441
2vprTDCTetracycline repressor protein class H/0.441
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
2xfiXFIBeta-secretase 13.4.23.460.441
2xupTZ5Acetylcholinesterase3.1.1.70.441
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.441
3aosJH2Hemolymph juvenile hormone binding protein/0.441
3b6pTMPThree-prime repair exonuclease 13.1.11.20.441
3bnkFMNFlavoredoxin/0.441
3c1kT15Prothrombin3.4.21.50.441
3c35KAIGlutamate receptor ionotropic, kainate 1/0.441
3eo8FMNPutative nitroreductase/0.441
3fpaDTBATP-dependent dethiobiotin synthetase BioD/0.441
3isjA8DPantothenate synthetase6.3.2.10.441
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.441
3ogxH1SPeptidoglycan recognition protein 1/0.441
3own3OXRenin3.4.23.150.441
3p84FMNPentaerythritol tetranitrate reductase/0.441
3tozNADShikimate dehydrogenase (NADP(+))/0.441
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
4b65FADL-ornithine N(5)-monooxygenase/0.441
4djaFAD(6-4) photolyase/0.441
4iaxLIZNeutrophil gelatinase-associated lipocalin/0.441
4loi1YCStimulator of interferon genes protein/0.441
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.441
4psbGA3Cytokinin-specific binding protein/0.441
4relKMPGlycosyltransferase/0.441
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
5c93ACPTwo-component system histidine protein kinase/0.441
4s0vSUVOrexin receptor type 2/0.441
1dliUDXUDP-glucose 6-dehydrogenase/0.440
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.440
1g5qASP_SER_TYR_THR_CYSEpidermin decarboxylase4.1.10.440
1gpeFADGlucose oxidase1.1.3.40.440
1hb1OCVIsopenicillin N synthase1.21.3.10.440
1kqgHQOFormate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit/0.440
1ypkCCRProthrombin3.4.21.50.440
2a9z26AAdenosine kinase2.7.1.200.440
2dftADPShikimate kinase2.7.1.710.440
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.440
2huxSAHDiphthine synthase/0.440
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.440
2rcyNAPPyrroline-5-carboxylate reductase/0.440
2vn1FK5Peptidylprolyl isomerase/0.440
2wf4ZY4Beta-secretase 13.4.23.460.440
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.440
2xukTZ5Acetylcholinesterase3.1.1.70.440
2xweAMFGlucosylceramidase3.2.1.450.440
3biy01KHistone acetyltransferase p300/0.440
3bw2FMNPutative 2-nitropropane dioxygenase/0.440
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.440
3fr28CAFatty acid-binding protein, adipocyte/0.440
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.440
3rn8RN8Glutamate receptor 2/0.440
3u8l09QAcetylcholine-binding protein/0.440
3uylTYDProbable NDP-rhamnosyltransferase/0.440
3vdqNAD3-hydroxybutyrate dehydrogenase/0.440
3vf60H6Glucokinase2.7.1.20.440
3w6hAZMCarbonic anhydrase 14.2.1.10.440
4b63NAPL-ornithine N(5)-monooxygenase/0.440
4b66NAPL-ornithine N(5)-monooxygenase/0.440
4b68NAPL-ornithine N(5)-monooxygenase/0.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.440
4df2FMNNADPH dehydrogenase/0.440
4ewo996Beta-secretase 13.4.23.460.440
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4ijrNDPD-arabinose dehydrogenase [NAD(P)+] heavy chain1.1.1.1170.440
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.440
4jv3N32Beta-ketoacyl synthase/0.440
4lzwTHMUridine phosphorylase/0.440
4py243EMethionine--tRNA ligase/0.440