sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4khn | XG4 | DNA-directed DNA polymerase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4khn | XG4 | DNA-directed DNA polymerase | / | 1.000 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.530 | |
| 4i9q | XG4 | DNA-directed DNA polymerase | / | 0.517 | |
| 1waj | 5GP | DNA-directed DNA polymerase | / | 0.494 | |
| 3cfo | GMP | DNA-directed DNA polymerase | / | 0.484 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.473 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.471 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.459 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.458 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.457 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.453 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.451 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.451 | |
| 3f90 | FMN | Flavodoxin | / | 0.446 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 4zqm | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 3f6s | FMN | Flavodoxin | / | 0.444 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.443 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.443 | |
| 3b5i | SAH | Indole-3-acetate O-methyltransferase 1 | / | 0.442 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.441 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.441 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4f79 | P53 | Putative phospho-beta-glucosidase | / | 0.440 |