scPDB - Distribution of Binding site Similarity values of 4kfj entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4kfj	1R0	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4kfj	1R0	Dihydrofolate reductase	1.5.1.3	1.000
4kd7	9DR	Dihydrofolate reductase	1.5.1.3	0.625
4kak	06U	Dihydrofolate reductase	1.5.1.3	0.611
4kbn	25U	Dihydrofolate reductase	1.5.1.3	0.590
3k47	D09	Dihydrofolate reductase	1.5.1.3	0.565
3nxo	D2B	Dihydrofolate reductase	1.5.1.3	0.558
3nxt	D2E	Dihydrofolate reductase	1.5.1.3	0.552
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.550
3nxv	D2F	Dihydrofolate reductase	1.5.1.3	0.542
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.540
1boz	PRD	Dihydrofolate reductase	1.5.1.3	0.533
3nxr	D2D	Dihydrofolate reductase	1.5.1.3	0.529
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.522
1s3w	TQT	Dihydrofolate reductase	1.5.1.3	0.514
3cse	N22	Uncharacterized protein	/	0.508
3nxy	D2H	Dihydrofolate reductase	1.5.1.3	0.508
4ddr	MMV	Dihydrofolate reductase	1.5.1.3	0.485
4qjc	IXE	Dihydrofolate reductase	1.5.1.3	0.485
1cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.484
1dlr	MXA	Dihydrofolate reductase	1.5.1.3	0.481
3qly	55V	Uncharacterized protein	/	0.481
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.479
3qlz	QLZ	Uncharacterized protein	/	0.478
1hfp	MOT	Dihydrofolate reductase	1.5.1.3	0.471
2cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.471
4ixe	IXE	Dihydrofolate reductase	1.5.1.3	0.470
3qlx	QLR	Uncharacterized protein	/	0.467
1pd8	CO4	Dihydrofolate reductase	1.5.1.3	0.466
3eem	53V	Uncharacterized protein	/	0.465
1u72	MTX	Dihydrofolate reductase	1.5.1.3	0.463
1vj3	TAB	Dihydrofolate reductase	1.5.1.3	0.461
4h97	53S	Dihydrofolate reductase	1.5.1.3	0.461
4h98	14Q	Uncharacterized protein	/	0.460
1dr4	HBI	Dihydrofolate reductase	1.5.1.3	0.459
4h96	14Q	Dihydrofolate reductase	1.5.1.3	0.459
3jsu	KA5	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.458
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.458
3ghv	GHC	Dihydrofolate reductase	1.5.1.3	0.457
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.455
1ohj	COP	Dihydrofolate reductase	1.5.1.3	0.455
3ntz	3TZ	Dihydrofolate reductase	1.5.1.3	0.455
3eek	53S	Uncharacterized protein	/	0.454
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.454
3l3r	OAG	Dihydrofolate reductase	1.5.1.3	0.453
2bl9	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.452
4h95	06U	Dihydrofolate reductase	1.5.1.3	0.451
1klk	PMD	Dihydrofolate reductase	1.5.1.3	0.449
3td8	D2R	Dihydrofolate reductase	1.5.1.3	0.449
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.448
1j3i	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.447
1kms	LIH	Dihydrofolate reductase	1.5.1.3	0.446
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.445
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.443
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.441
4eil	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.441
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.440
2w3m	FOL	Dihydrofolate reductase	1.5.1.3	0.440