sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 1.000 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.460 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.460 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.453 | |
| 3bhr | THG | Thymidylate synthase | / | 0.451 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.449 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.446 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.446 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.444 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.442 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.440 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.440 |