scPDB - Distribution of Binding site Similarity values of 4k4e entry / Site 2

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4k4e	K4E	Tankyrase-1	2.4.2.30

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4k4e	K4E	Tankyrase-1	2.4.2.30	1.000
4li8	1XQ	Tankyrase-1	2.4.2.30	0.554
4k4f	K4F	Tankyrase-1	2.4.2.30	0.545
4li7	1XP	Tankyrase-1	2.4.2.30	0.543
4mt9	2D6	Tankyrase-1	2.4.2.30	0.539
4hyf	1AK	Tankyrase-2	2.4.2.30	0.537
4n4t	2GV	Tankyrase-1	2.4.2.30	0.534
4bj9	UHB	Tankyrase-2	2.4.2.30	0.532
4i9i	1DY	Tankyrase-1	2.4.2.30	0.532
4msg	2C6	Tankyrase-1	2.4.2.30	0.522
4li6	1XO	Tankyrase-1	2.4.2.30	0.512
4n4v	2GY	Tankyrase-1	2.4.2.30	0.507
4dvi	2IW	Tankyrase-1	2.4.2.30	0.502
4bfp	SWY	Tankyrase-2	2.4.2.30	0.496
4msk	2C8	Tankyrase-1	2.4.2.30	0.481
4tkg	09L	Tankyrase-2	2.4.2.30	0.462